P38 MAPK Promotes Migration and Metastatic Activity of BRAF Mutant Melanoma Cells by Inducing Degradation of PMCA4b

Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance

(2019) Shun Li et al.   Nature Communications

Calcium signaling and the therapeutic targeting of cancer cells

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Integrins as therapeutic targets in the organ-specific metastasis of human malignant melanoma

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Role of p38 MAPK in disease relapse and therapeutic resistance by maintenance of cancer stem cells in head and neck squamous cell carcinoma

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Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein

(2018) Gergő Vőfély et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Expression of calcium pumps is differentially regulated by histone deacetylase inhibitors and estrogen receptor alpha in breast cancer cells

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Advances in multicellular spheroids formation

(2017) X. Cui et al.   Journal of the Royal Society Interface

Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca2+ Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK

(2017) Luca Hegedüs et al.   Frontiers in Oncology

Regulation of the Plasma Membrane Calcium ATPases by the actin cytoskeleton

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Multifaceted plasma membrane Ca 2+ pumps: From structure to intracellular Ca 2+ handling and cancer

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3D tumor spheroids: an overview on the tools and techniques used for their analysis

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Alterations of calcium homeostasis in cancer cells

(2016) Saverio Marchi et al.   CURRENT OPINION IN PHARMACOLOGY

The plasma membrane Ca2+ pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells

(2016) Luca Hegedũs et al.   INTERNATIONAL JOURNAL OF CANCER

The plethora of PMCA isoforms: Alternative splicing and differential expression

(2015) Joachim Krebs   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Plasma membrane Ca2+-ATPases can shape the pattern of Ca2+transients induced by store-operated Ca2+entry

(2015) Katalin Pászty et al.   Science Signaling

Ca2+Signaling in Cytoskeletal Reorganization, Cell Migration, and Cancer Metastasis

(2015) Feng-Chiao Tsai et al.   Biomed Research International

Calcium Channel Expression and Applicability as Targeted Therapies in Melanoma

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Plasma membrane Ca2+-ATPases can shape the pattern of Ca2+transients induced by store-operated Ca2+entry

(2015) Katalin Pászty et al.   Science Signaling

PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer

(2015) Yanjie Zhang et al.   EBioMedicine

Histone deacetylase inhibitor- and PMA-induced upregulation of PMCA4b enhances Ca2+ clearance from MCF-7 breast cancer cells

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Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma

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A polarized Ca2+, diacylglycerol and STIM1 signalling system regulates directed cell migration

(2014) Feng-Chiao Tsai et al.   NATURE CELL BIOLOGY

Multiplexing Spheroid Volume, Resazurin and Acid Phosphatase Viability Assays for High-Throughput Screening of Tumour Spheroids and Stem Cell Neurospheres

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Reversal of Anchorage-Independent Multicellular Spheroid into a Monolayer Mimics a Metastatic Model

(2014) Rani Kunjithapatham et al.   Scientific Reports

A C-terminal di-leucine motif controls plasma membrane expression of PMCA4b

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Sorafenib inhibits p38α activity in colorectal cancer cells and synergizes with the DFG-in inhibitor SB202190 to increase apoptotic response

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Plasma Membrane Calcium ATPase Expression in Human Colon Multistep Carcinogenesis

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Calcium Channels and Pumps in Cancer: Changes and Consequences

(2012) Gregory R. Monteith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of BRAF V600 mutation in melanoma

(2012) Paolo A Ascierto et al.   Journal of Translational Medicine

Raf kinases in cancer–roles and therapeutic opportunities

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Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

Review: Ultraviolet radiation and skin cancer

(2010) Deevya L. Narayanan et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

p38α Is Required for Ovarian Cancer Cell Metabolism and Survival

(2010) Antonio Matrone et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Ion channels and the hallmarks of cancer

(2010) Natalia Prevarskaya et al.   TRENDS IN MOLECULAR MEDICINE

Positive crosstalk between ERK and p38 in melanoma stimulates migration and in vivo proliferation

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