Stimulation of Fibronectin Matrix Assembly by Lysine Acetylation

Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation

(2019) Bogi Karbech Hansen et al.   Nature Communications

β1D-integrin splice variant stabilizes integrin dynamics and reduces integrin signaling by limiting paxillin recruitment

(2019) Martinho Soto-Ribeiro et al.   JOURNAL OF CELL SCIENCE

Therapeutic approaches to control tissue repair and fibrosis: Extracellular matrix as a game changer

(2018) Mariëlle Walraven et al.   MATRIX BIOLOGY

Histone Deacetylase Inhibitors and Diabetic Kidney Disease

(2018) Mitchell Hadden et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Integrin activation by talin, kindlin and mechanical forces

(2018) Zhiqi Sun et al.   NATURE CELL BIOLOGY

Disruption of fibronectin matrix affects type IV collagen, fibrillin and laminin deposition into extracellular matrix of human trabecular meshwork (HTM) cells

(2017) Mark S. Filla et al.   EXPERIMENTAL EYE RESEARCH

Critical role of the cAMP-PKA pathway in hyperglycemia-induced epigenetic activation of fibrogenic program in the kidney

(2017) Dilip K. Deb et al.   FASEB JOURNAL

Stimulatory effects of advanced glycation endproducts (AGEs) on fibronectin matrix assembly

(2017) Alexandra K. Pastino et al.   MATRIX BIOLOGY

Structural basis of kindlin-mediated integrin recognition and activation

(2017) Huadong Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minireview: Fibronectin in retinal disease

(2016) Charles G Miller et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

(2016) Marina Theodosiou et al.   eLife

Acetyl Coenzyme A: A Central Metabolite and Second Messenger

(2015) Federico Pietrocola et al.   Cell Metabolism

Nascent Integrin Adhesions Form on All Matrix Rigidities after Integrin Activation

(2015) Rishita Changede et al.   DEVELOPMENTAL CELL

Prevalence of chronic kidney disease among individuals with diabetes in the SUPREME-DM Project, 2005–2011

(2015) Emily B. Schroeder et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Role of Transcription Factor Acetylation in Diabetic Kidney Disease

(2014) R. Liu et al.   DIABETES

Diabetes Induces Lysine Acetylation of Intermediary Metabolism Enzymes in the Kidney

(2014) H. Kosanam et al.   DIABETES

Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells

(2014) Charles G. Miller et al.   MOLECULAR BIOLOGY OF THE CELL

Targeting bromodomains: epigenetic readers of lysine acetylation

(2014) Panagis Filippakopoulos et al.   NATURE REVIEWS DRUG DISCOVERY

Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli

(2014) F. Impens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MYPT1 regulates contractility and microtubule acetylation to modulate integrin adhesions and matrix assembly

(2014) E. Emily Joo et al.   Nature Communications

Sirt1 Activation Ameliorates Renal Fibrosis by Inhibiting the TGF-β/Smad3 Pathway

(2013) Xin-Zhong Huang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation

(2013) Weizhi Liu et al.   MOLECULAR CELL

Resveratrol Attenuates Diabetic Nephropathy via Modulating Angiogenesis

(2013) Donghai Wen et al.   PLoS One

Cell Adhesion: A FERM Grasp of the Tail Sorts Out Integrins

(2012) Nina N. Brahme et al.   CURRENT BIOLOGY

Resveratrol ameliorates early diabetic nephropathy associated with suppression of augmented TGF-β/smad and ERK1/2 signaling in streptozotocin-induced diabetic rats

(2011) Kuan-Hsing Chen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Osteoblast mineralization requires β1 integrin/ICAP-1–dependent fibronectin deposition

(2011) Molly Brunner et al.   JOURNAL OF CELL BIOLOGY

Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins

(2011) H. Qu et al.   JOURNAL OF CELL SCIENCE

Assembly of Fibronectin Extracellular Matrix

(2010) Purva Singh et al.   Annual Review of Cell and Developmental Biology

β1A Integrin Is a Master Regulator of Invadosome Organization and Function

(2010) Olivier Destaing et al.   MOLECULAR BIOLOGY OF THE CELL

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction

(2009) Nicholas J Anthis et al.   EMBO JOURNAL

Kindlin-1 and -2 Directly Bind the C-terminal Region of β Integrin Cytoplasmic Tails and Exert Integrin-specific Activation Effects

(2009) David S. Harburger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

New insights into the mechanisms of fibrosis and sclerosis in diabetic nephropathy

(2008) Frank C. Brosius   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS