FOXOs attenuate bone formation by suppressing Wnt signaling

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Expanded Granulocyte/Monocyte Compartment in Myeloid-Specific Triple FoxO Knockout Increases Oxidative Stress and Accelerates Atherosclerosis in Mice

(2013) Kyoichiro Tsuchiya et al.   CIRCULATION RESEARCH

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration

(2012) Dongsu Park et al.   Cell Stem Cell

Cross-talk between Insulin and Wnt Signaling in Preadipocytes

(2012) Jane Palsgaard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of wnt/β-catenin signaling causes cell fate shift of preosteoblasts from osteoblasts to adipocytes

(2012) Lige Song et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Generation of functional insulin-producing cells in the gut by Foxo1 ablation

(2012) Chutima Talchai et al.   NATURE GENETICS

Update on Wnt signaling in bone cell biology and bone disease

(2011) David G. Monroe et al.   GENE

Glucocorticoids and Tumor Necrosis Factor α Increase Oxidative Stress and Suppress Wnt Protein Signaling in Osteoblasts

(2011) Maria Almeida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol promotes osteogenesis of human mesenchymal stem cells by upregulating RUNX2 gene expression via the SIRT1/FOXO3A axis

(2011) Pei-Chi Tseng et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Foxo1 is required in mouse spermatogonial stem cells for their maintenance and the initiation of spermatogenesis

(2011) Meredith J. Goertz et al.   JOURNAL OF CLINICAL INVESTIGATION

FOXO1 is an essential regulator of pluripotency in human embryonic stem cells

(2011) Xin Zhang et al.   NATURE CELL BIOLOGY

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Wnt Signaling Regulates Hepatic Metabolism

(2011) H. Liu et al.   Science Signaling

Decreased body weight in young Osterix-Cre transgenic mice results in delayed cortical bone expansion and accrual

(2011) Rachel A. Davey et al.   TRANSGENIC RESEARCH

Insulin Signaling in Osteoblasts Integrates Bone Remodeling and Energy Metabolism

(2010) Mathieu Ferron et al.   CELL

Skeletal aging and the adipocyte program

(2010) Beata Lecka-Czernik et al.   CELL CYCLE

FoxO-Mediated Defense against Oxidative Stress in Osteoblasts Is Indispensable for Skeletal Homeostasis in Mice

(2010) Elena Ambrogini et al.   Cell Metabolism

FoxO1 Is a Positive Regulator of Bone Formation by Favoring Protein Synthesis and Resistance to Oxidative Stress in Osteoblasts

(2010) Marie-Therese Rached et al.   Cell Metabolism

Wnt Signaling and Aging-Related Heart Disorders

(2010) Atsuhiko T. Naito et al.   CIRCULATION RESEARCH

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

(2010) Christa Maes et al.   DEVELOPMENTAL CELL

From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis

(2010) Stavros C. Manolagas   ENDOCRINE REVIEWS

Foxo1, a Novel Regulator of Osteoblast Differentiation and Skeletogenesis

(2010) Cristina C. Teixeira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Linking Alzheimer's disease to insulin resistance: the FoxO response to oxidative stress

(2010) K N Manolopoulos et al.   MOLECULAR PSYCHIATRY

PPARγ: a circadian transcription factor in adipogenesis and osteogenesis

(2010) Masanobu Kawai et al.   Nature Reviews Endocrinology

Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice

(2009) Robert S. Weinstein et al.   AGING CELL

FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis

(2009) Ji-hye Paik et al.   Cell Stem Cell

FoxO3 Regulates Neural Stem Cell Homeostasis

(2009) Valérie M. Renault et al.   Cell Stem Cell

Increased Lipid Oxidation Causes Oxidative Stress, Increased Peroxisome Proliferator-activated Receptor-γ Expression, and Diminished Pro-osteogenic Wnt Signaling in the Skeleton

(2009) Maria Almeida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Pancreatic Juxtaductal Endocrine Cell Formation by FoxO1

(2009) T. Kitamura et al.   MOLECULAR AND CELLULAR BIOLOGY

Which way does the Wnt blow? Exploring the duality of canonical Wnt signaling on cellular aging

(2008) Nathan A. DeCarolis et al.   BIOESSAYS

FoxO transcription factors in the maintenance of cellular homeostasis during aging

(2008) Dervis AM Salih et al.   CURRENT OPINION IN CELL BIOLOGY

The WNT signalling pathway and diabetes mellitus

(2008) T. Jin   DIABETOLOGIA

Interaction of FOXO with β-Catenin Inhibits β-Catenin/T Cell Factor Activity

(2008) Diana Hoogeboom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure/function relationships underlying regulation of FOXO transcription factors

(2008) T Obsil et al.   ONCOGENE

FOXO-binding partners: it takes two to tango

(2008) K E van der Vos et al.   ONCOGENE

Many forks in the path: cycling with FoxO

(2008) K K Ho et al.   ONCOGENE