Correlation of PKM2 and CD44 Protein Expression with Poor Prognosis in Platinum-Treated Epithelial Ovarian Cancer: A Retrospective Study

Prognostic Value of CD44 and Its Isoforms in Advanced Cancer: A Systematic Meta-Analysis With Trial Sequential Analysis

(2019) Susu Han et al.   Frontiers in Oncology

Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation

(2019) Jamie A Macpherson et al.   eLife

Pyruvate kinase M2 inhibits the progression of bladder cancer by targeting MAKP pathway

(2018) Baofa Hong et al.   Journal of Cancer Research and Therapeutics

The biology and role of CD44 in cancer progression: therapeutic implications

(2018) Chen Chen et al.   Journal of Hematology & Oncology

Pyruvate kinase M2 fuels multiple aspects of cancer cells: from cellular metabolism, transcriptional regulation to extracellular signaling

(2018) Ming-Chuan Hsu et al.   Molecular Cancer

Overexpression of Pyruvate Kinase Type M2 (PKM2) Promotes Ovarian Cancer Cell Growth and Survival Via Regulation of Cell Cycle Progression Related with Upregulated CCND1 and Downregulated CDKN1A Expression

(2018) Bin Zheng et al.   MEDICAL SCIENCE MONITOR

Corrigendum: Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

(2017) Weiwei Yang et al.   NATURE

PKM2 in carcinogenesis and oncotherapy

(2017) Xia He et al.   Oncotarget

Knockdown of PKM2 and GLS1 expression can significantly reverse oxaliplatin-resistance in colorectal cancer cells

(2017) Wei-Qun Lu et al.   Oncotarget

The molecular mechanisms of chemoresistance in cancers

(2017) Hua-Chuan Zheng   Oncotarget

Exosomes Promote Ovarian Cancer Cell Invasion through Transfer of CD44 to Peritoneal Mesothelial Cells

(2016) Koji Nakamura et al.   MOLECULAR CANCER RESEARCH

PKM2 as a biomarker for chemosensitivity to front-line platinum-based chemotherapy in patients with metastatic non-small-cell lung cancer

(2014) C Papadaki et al.   BRITISH JOURNAL OF CANCER

PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis

(2014) Weiwei Yang et al.   CELL

SAICAR Induces Protein Kinase Activity of PKM2 that Is Necessary for Sustained Proliferative Signaling of Cancer Cells

(2014) Kirstie E. Keller et al.   MOLECULAR CELL

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Modulation of Glucose Metabolism by CD44 Contributes to Antioxidant Status and Drug Resistance in Cancer Cells

(2012) M. Tamada et al.   CANCER RESEARCH

Pyruvate Kinase M2: Multiple Faces for Conferring Benefits on Cancer Cells

(2012) M. Tamada et al.   CLINICAL CANCER RESEARCH

Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase

(2012) Xueliang Gao et al.   MOLECULAR CELL

When more is less

(2012) Lei Jiang et al.   NATURE

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

(2012) Dimitrios Anastasiou et al.   Nature Chemical Biology

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Role of Versican, Hyaluronan and CD44 in Ovarian Cancer Metastasis

(2011) Miranda Ween et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Impact of KRAS, BRAF, PIK3CA Mutations, PTEN, AREG, EREG Expression and Skin Rash in ≥2nd Line Cetuximab-Based Therapy of Colorectal Cancer Patients

(2011) Zacharenia Saridaki et al.   PLoS One

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

(2011) D. Anastasiou et al.   SCIENCE

Efficacy of RNAi targeting of pyruvate kinase M2 combined with cisplatin in a lung cancer model

(2010) Wenhao Guo et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Tumoral Expression of TXR1 and TSP1 Predicts Overall Survival of Patients with Lung Adenocarcinoma Treated with First-line Docetaxel-Gemcitabine Regimen

(2009) C. Papadaki et al.   CLINICAL CANCER RESEARCH

Current FIGO staging for cancer of the vagina, fallopian tube, ovary, and gestational trophoblastic neoplasia

(2009)   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

A proteomic approach links decreased pyruvate kinase M2 expression to oxaliplatin resistance in patients with colorectal cancer and in human cell lines

(2009) E. Martinez-Balibrea et al.   MOLECULAR CANCER THERAPEUTICS

Pyruvate kinase M2 is a phosphotyrosine-binding protein

(2008) Heather R. Christofk et al.   NATURE

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE