- Home
- Publications
- Publication Search
- Publication Details
Title
Bioinspired design of a robust d3-methylating agent
Authors
Keywords
-
Journal
Science Advances
Volume 6, Issue 19, Pages eaba0946
Publisher
American Association for the Advancement of Science (AAAS)
Online
2020-05-09
DOI
10.1126/sciadv.aba0946
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Applications of deuterium in medicinal chemistry
- (2019) Tracey Pirali et al. JOURNAL OF MEDICINAL CHEMISTRY
- Trideuteromethylation Enabled by a Sulfoxonium Metathesis Reaction
- (2019) Zuyuan Shen et al. ORGANIC LETTERS
- A Very Strong Methylation Agent: [Me2Cl][Al(OTeF5)4]
- (2019) Sebastian Hasenstab-Riedel et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- TEMPO–Me: An Electrochemically Activated Methylating Agent
- (2019) Philip L. Norcott et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Continuous‐Flow Hydrogenation and Reductive Deuteration of Nitriles: a Simple Access to α,α‐Dideutero Amines
- (2019) Rebeka Mészáros et al. ChemPlusChem
- Reductive Deuteration of Nitriles Using D2O as a Deuterium Source
- (2019) Yuxuan Ding et al. JOURNAL OF ORGANIC CHEMISTRY
- Selective Methylation of Arenes: A Radical C−H Functionalization/Cross-Coupling Sequence
- (2018) Fabien Serpier et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Selective α-Monomethylation by an Amine-Borane/N,N-Dimethylformamide System as the Methyl Source
- (2018) Hui-Min Xia et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- C−H Functionalisation for Hydrogen Isotope Exchange
- (2018) Jens Atzrodt et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Reduction and Reductive Deuteration of Tertiary Amides Mediated by Sodium Dispersions with Distinct Proton Donor-Dependent Chemoselectivity
- (2018) Bin Zhang et al. JOURNAL OF ORGANIC CHEMISTRY
- A General Strategy for Site-Selective Incorporation of Deuterium and Tritium into Pyridines, Diazines, and Pharmaceuticals
- (2018) J. Luke Koniarczyk et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Sulfonium Salts as Alkylating Agents for Palladium-Catalyzed Direct Ortho Alkylation of Anilides and Aromatic Ureas
- (2018) Dániel Cs. Simkó et al. ORGANIC LETTERS
- Iron-Mediated Azidomethylation or Azidotrideuteromethylation of Active Alkenes with Azidotrimethylsilane and Dimethyl Sulfoxide
- (2018) Rui Zhang et al. ADVANCED SYNTHESIS & CATALYSIS
- Reductive Deuteration of Nitriles: The Synthesis of α,α-Dideuterio Amines by Sodium-Mediated Electron Transfer Reactions
- (2018) Yuxuan Ding et al. JOURNAL OF ORGANIC CHEMISTRY
- General and Practical Potassium Methoxide/Disilane-Mediated Dehalogenative Deuteration of (Hetero)Arylhalides
- (2018) Xin Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Deoxygenative Deuteration of Carboxylic Acids with D2 O
- (2018) Muliang Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Trimethylphosphate as a Methylating Agent for Cross Coupling: A Slow-Release Mechanism for the Methylation of Arylboronic Esters
- (2018) Zhi-Tao He et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Powerful, Thermally Stable, One-Pot-Preparable, and Recyclable Electrophilic Trifluoromethylating Agents: 2,8-Difluoro- and 2,3,7,8-Tetrafluoro-S-(trifluoromethyl)dibenzothiophenium Salts
- (2017) Teruo Umemoto et al. JOURNAL OF ORGANIC CHEMISTRY
- Radical Deuteration with D2O: Catalysis and Mechanistic Insights
- (2017) Valentin Soulard et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Chemical and structural effects of base modifications in messenger RNA
- (2017) Emily M. Harcourt et al. NATURE
- First deuterated drug approved
- (2017) Charles Schmidt NATURE BIOTECHNOLOGY
- Transition-Metal-Free Regioselective Alkylation of Pyridine N -Oxides Using 1,1-Diborylalkanes as Alkylating Reagents
- (2016) Woohyun Jo et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Nickel-Catalyzed Methylation of Aryl Halides with Deuterated Methyl Iodide
- (2016) Lu Hu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Radical trideuteromethylation with deuterated dimethyl sulfoxide in the synthesis of heterocycles and labelled building blocks
- (2016) Roberta Caporaso et al. CHEMICAL COMMUNICATIONS
- Deuterated drugs draw heavier backing
- (2016) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Palladium-Assisted “Aromatic Metamorphosis” of Dibenzothiophenes into Triphenylenes
- (2015) Dhananjayan Vasu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Isotope chemistry; a useful tool in the drug discovery arsenal
- (2015) Charles S. Elmore et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Radical S-Adenosylmethionine Enzymes
- (2014) Joan B. Broderick et al. CHEMICAL REVIEWS
- C–H Methylation of Heteroarenes Inspired by Radical SAM Methyl Transferase
- (2014) Jinghan Gui et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Selective Synthesis of α,α-Dideuterio Alcohols by the Reduction of Carboxylic Acids Using SmI2 and D2O as Deuterium Source under SET Conditions
- (2014) Michal Szostak et al. ORGANIC LETTERS
- Using Deuterium in Drug Discovery: Leaving the Label in the Drug
- (2013) Thomas G. Gant JOURNAL OF MEDICINAL CHEMISTRY
- Deuterated Clopidogrel Analogues as a New Generation of Antiplatelet Agents
- (2013) Yaoqiu Zhu et al. ACS Medicinal Chemistry Letters
- Structural Insights into Radical Generation by the Radical SAM Superfamily
- (2011) Jessica L. Vey et al. CHEMICAL REVIEWS
- The Methylation Effect in Medicinal Chemistry
- (2011) Eliezer J. Barreiro et al. CHEMICAL REVIEWS
- Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation
- (2011) Li Zhang et al. NATURE
- Synthesis of 19-trideuteratedent-testosterone and the GABAAreceptor potentiatorsent-androsterone andent-etiocholanolone
- (2008) Shirisha Komarapuri et al. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started