Conjugation of Synthetic Trisaccharide of Staphylococcus aureus Type 8 Capsular Polysaccharide Elicits Antibodies Recognizing Intact Bacterium

Molecular epidemiology and expression of capsular polysaccharides in Staphylococcus aureus clinical isolates in the United States

(2019) Naglaa Mohamed et al.   PLoS One

Considering the ‘Alternatives’ for Next-Generation Anti-Staphylococcus aureus Vaccine Development

(2019) Eóin C. O’Brien et al.   TRENDS IN MOLECULAR MEDICINE

Recent advances in Staphylococcus aureus infection: focus on vaccine development

(2019) Shamshul Ansari et al.   Infection and Drug Resistance

Total Syntheses of Conjugation-Ready Trisaccharide Repeating Units of Pseudomonas aeruginosa O11 and Staphylococcus aureus Type 5 Capsular Polysaccharide for Vaccine Development

(2019) Archanamayee Behera et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Glycosylation as Key to the Chemical Synthesis of an Outer Core Octasaccharide of Helicobacter pylori

(2018) Xiaopeng Zou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Identification of the Minimal Glycotope of Streptococcus pneumoniae 7F Capsular Polysaccharide using Synthetic Oligosaccharides

(2018) Petra Ménová et al.   CHEMISTRY-A EUROPEAN JOURNAL

Total Synthesis of a Densely Functionalized Plesiomonas shigelloides Serotype 51 Aminoglycoside Trisaccharide Antigen

(2018) Chunjun Qin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Master mechanisms of Staphylococcus aureus : consider its excellent protective mechanisms hindering vaccine development!

(2018) Xu Zhang et al.   MICROBIOLOGICAL RESEARCH

Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity

(2018) David Gerlach et al.   NATURE

Improving vaccines against Streptococcus pneumoniae using synthetic glycans

(2018) Paulina Kaplonek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of monoclonal antibodies against Sj29 and its possible application for schistosomiasis diagnosis

(2017) Cui-Ping Ren et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Mapping the Reactivity and Selectivity of 2-Azidofucosyl Donors for the Assembly of N-Acetylfucosamine-Containing Bacterial Oligosaccharides

(2017) Bas Hagen et al.   JOURNAL OF ORGANIC CHEMISTRY

A Streptococcus pneumoniae Type 2 Oligosaccharide Glycoconjugate Elicits Opsonic Antibodies and Is Protective in an Animal Model of Invasive Pneumococcal Disease

(2017) Madhu Emmadi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Semisynthetic glycoconjugate vaccine candidate againstStreptococcus pneumoniaeserotype 5

(2017) Marilda P. Lisboa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine

(2017) Benjamin Schumann et al.   Science Translational Medicine

Safety, tolerability, and immunogenicity of a single dose 4-antigen or 3-antigen Staphylococcus aureus vaccine in healthy older adults: Results of a randomised trial

(2017) C. Buddy Creech et al.   VACCINE

SA4Ag, a 4-antigen Staphylococcus aureus vaccine, rapidly induces high levels of bacteria-killing antibodies

(2017) Elizabeth Begier et al.   VACCINE

Safety, tolerability, and immunogenicity of a 4-antigen Staphylococcus aureus vaccine (SA4Ag): Results from a first-in-human randomised, placebo-controlled phase 1/2 study

(2017) Robert W. Frenck et al.   VACCINE

Synthesis of the Repeating Unit of Capsular Polysaccharide Staphylococcus aureus Type 5 To Study Chemical Activation and Conjugation of Native CP5

(2016) Jagodige P. Yasomanee et al.   JOURNAL OF ORGANIC CHEMISTRY

An antibacterial vaccination strategy based on a glycoconjugate containing the core lipopolysaccharide tetrasaccharide Hep2Kdo2

(2016) Lingbing Kong et al.   Nature Chemistry

Multivalent display of minimal Clostridium difficile glycan epitopes mimics antigenic properties of larger glycans

(2016) Felix Broecker et al.   Nature Communications

Fully Synthetic Self-Adjuvanting α-2,9-Oligosialic Acid Based Conjugate Vaccines against Group C Meningitis

(2016) Guochao Liao et al.   ACS Central Science

Chemical Synthesis Elucidates the Immunological Importance of a Pyruvate Modification in the Capsular Polysaccharide ofStreptococcus pneumoniaeSerotype 4

(2015) Claney L. Pereira et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antigenic Potential of a Highly Conserved Neisseria meningitidis Lipopolysaccharide Inner Core Structure Defined by Chemical Synthesis

(2015) Anika Reinhardt et al.   CHEMISTRY & BIOLOGY

Chemical synthesis of the outer core oligosaccharide of Escherichia coli R3 and immunological evaluation

(2015) Wenjing Shang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Concise Synthesis of the Repeating Unit of Capsular Polysaccharide Staphylococcus aureus Type 8

(2015) Satsawat Visansirikul et al.   ORGANIC LETTERS

Efficacy profile of a bivalent Staphylococcus aureusglycoconjugated vaccine in adults on hemodialysis: Phase III randomized study

(2015) Ali Fattom et al.   Human Vaccines & Immunotherapeutics

Epitope Recognition of Antibodies against a Yersinia pestis Lipopolysaccharide Trisaccharide Component

(2014) Felix Broecker et al.   ACS Chemical Biology

Chemical Biology Approaches to Designing Defined Carbohydrate Vaccines

(2014) Chakkumkal Anish et al.   CHEMISTRY & BIOLOGY

Total Synthesis of Anticoagulant Pentasaccharide Fondaparinux

(2014) Tiehai Li et al.   ChemMedChem

Synthesis of conjugation-ready zwitterionic oligosaccharides by chemoselective thioglycoside activation

(2014) B. Schumann et al.   Chemical Science

Synthesis of a chlorogenin glycoside library using an orthogonal protecting group strategy

(2013) Ying-Hsin Wang et al.   CARBOHYDRATE RESEARCH

Synthesis of Staphylococcus aureus type 5 capsular polysaccharide repeating unit using novel l-FucNAc and d-FucNAc synthons and immunochemical evaluation

(2012) Elisa Danieli et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Biochemical and biological characteristics of cross-reacting material 197 (CRM197), a non-toxic mutant of diphtheria toxin: Use as a conjugation protein in vaccines and other potential clinical applications

(2011) Michael Bröker et al.   BIOLOGICALS

Safety and immunogenicity of a combined hepatitis B virus-Haemophilus influenzaetype B vaccine comprising a synthetic antigen in healthy adults

(2011) Arístides Aguilar Betancourt et al.   Human vaccines & immunotherapeutics

How Bacterial Carbohydrates Influence the Adaptive Immune System

(2009) Fikri Y. Avci et al.   Annual Review of Immunology

Recent advances in carbohydrate-based vaccines

(2009) Marie-Lyn Hecht et al.   CURRENT OPINION IN CHEMICAL BIOLOGY