Synthesis of conjugation-ready zwitterionic oligosaccharides by chemoselective thioglycoside activation

Synthesis of a trisaccharide repeat of the zwitterionic Sp1 capsular polysaccharide utilizing 2-azido-4-benzylamino-4N,3-O-carbonyl-2,4,6-trideoxy-d-galactopyranosyl trichloroacetimidate

(2013) Ithayavani Iynkkaran et al.   CARBOHYDRATE RESEARCH

Total Synthesis of theEscherichia coliO111O-Specific Polysaccharide Repeating Unit

(2013) Oliviana Calin et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of Carbohydrate-Functionalised Sequence-Defined Oligo(amidoamine)s by Photochemical ThiolEne Coupling in a Continuous Flow Reactor

(2013) Felix Wojcik et al.   CHEMISTRY-A EUROPEAN JOURNAL

Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer

(2013) Y.-L. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Capsular polysaccharides are an important immune evasion mechanism forStaphylococcus aureus

(2013) Jasdeep S. Nanra et al.   Human Vaccines & Immunotherapeutics

In celebration of Sydney M. Finegold, M.D.: Bacteroides fragilis in the colon: The good & the bad

(2012) Cynthia L. Sears   ANAEROBE

Multigram-scale synthesis of an orthogonally protected 2-acetamido-4-amino-2,4,6-trideoxy-d-galactose (AAT) building block

(2012) A.E. Christina et al.   CARBOHYDRATE RESEARCH

On the Reactivity and Selectivity of Galacturonic Acid Lactones

(2012) Alphert E. Christina et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Chemical Synthesis and Immunological Evaluation of the Inner Core Oligosaccharide of Francisella tularensis

(2012) Thomas J. Boltje et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gold nanoparticles as carriers for a syntheticStreptococcus pneumoniaetype 14 conjugate vaccine

(2012) Dodi Safari et al.   Nanomedicine

Dimethylformamide: An Unusual Glycosylation Modulator

(2011) Shao-Ru Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Coordinated Synthesis and Conjugation Strategy for the Preparation of Homogeneous Glycoconjugate Vaccine Candidates

(2011) Elizabeth J. Grayson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective reductive openings of 4,6-benzylidene acetals: synthetic and mechanistic aspects

(2011) Markus Ohlin et al.   CARBOHYDRATE RESEARCH

Progress toward developing a carbohydrate-conjugate vaccine against Clostridium difficile ribotype 027: synthesis of the cell-surface polysaccharide PS-I repeating unit

(2011) Christopher E. Martin et al.   CHEMICAL COMMUNICATIONS

A Possible Oligosaccharide-Conjugate Vaccine Candidate for Clostridium difficile Is Antigenic and Immunogenic

(2011) Matthias A. Oberli et al.   CHEMISTRY & BIOLOGY

Regulation of innate and adaptive immunity by the commensal microbiota

(2011) Irene Jarchum et al.   CURRENT OPINION IN IMMUNOLOGY

Synthesis of Neoglycoconjugates Containing 4-Amino-4-deoxy-L-arabinose Epitopes Corresponding to the Inner Core of Burkholderia and Proteus Lipopolysaccharides

(2011) Markus Blaukopf et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The yin yang of bacterial polysaccharides: lessons learned from B. fragilis PSA

(2011) Neeraj K. Surana et al.   IMMUNOLOGICAL REVIEWS

Galacturonic Acid Lactones in the Synthesis of All Trisaccharide Repeating Units of the Zwitterionic Polysaccharide Sp1

(2011) Alphert E. Christina et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Molecular Recognition Studies of the HNK-1 Trisaccharide and Related Oligosaccharides. The Specificity of Monoclonal Anti-HNK-1 Antibodies as Assessed by Surface Plasmon Resonance and STD NMR

(2011) Yury E. Tsvetkov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Determination of Carbohydrate-Binding Preferences of Human Galectins with Carbohydrate Microarrays

(2010) Tim Horlacher  et al.   CHEMBIOCHEM

Synthesis of Monomeric and Dimeric Repeating Units of the Zwitterionic Type 1 Capsular Polysaccharide fromStreptococcus pneumoniae

(2010) Xiangyang Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of the Core Structure of the Lipoteichoic Acid of Streptococcus pneumoniae

(2010) Christian Marcus Pedersen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Perfectly Regioselective and Sequential Protection of Glucopyranosides

(2010) Wataru Muramatsu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Orientations of the Bacteroides fragilis Capsular Polysaccharide Biosynthesis Locus Promoters during Symbiosis and Infection

(2010) E. B. Troy et al.   JOURNAL OF BACTERIOLOGY

Erosion of Stereochemical Control with Increasing Nucleophilicity:O-Glycosylation at the Diffusion Limit

(2010) Matthew G. Beaver et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Solution-Phase Conformation of the RG-I Fragment of the Plant Polysaccharide Pectin Reveals a Modification-Modulated Assembly Mechanism

(2010) Eoin M. Scanlan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Analysis of Carbohydrate−Antibody Interactions: Case Study Using aBacillus anthracisTetrasaccharide

(2010) Matthias A. Oberli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of the Bacteroides fragilis Zwitterionic Polysaccharide A1 Repeating Unit

(2010) Rajan Pragani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Surface Characterization of Carbohydrate Microarrays

(2010) David J. Scurr et al.   LANGMUIR

To be or not to be a pathogen: that is the mucosally relevant question

(2010) P J Sansonetti   Mucosal Immunology

De Novo Synthesis of a 2-Acetamido-4-amino-2,4,6-trideoxy-d-galactose (AAT) Building Block for the Preparation of aBacteroides fragilisA1 Polysaccharide Fragment

(2010) Rajan Pragani et al.   ORGANIC LETTERS

Has the Microbiota Played a Critical Role in the Evolution of the Adaptive Immune System?

(2010) Y. K. Lee et al.   SCIENCE

Evaluation of a Group A Streptococcus synthetic oligosaccharide as vaccine candidate

(2010) Anna Kabanova et al.   VACCINE

Comparative bioinformatics analysis of the mammalian and bacterial glycomes

(2010) Alexander Adibekian et al.   Chemical Science

How Bacterial Carbohydrates Influence the Adaptive Immune System

(2009) Fikri Y. Avci et al.   Annual Review of Immunology

Beneficial effects of Bacteroides fragilis polysaccharides on the immune system

(2009) Erin et al.   Frontiers in Bioscience-Landmark

Toll-like receptor 2 dependent immunogenicity of glycoconjugate vaccines containing chemically derived zwitterionic polysaccharides

(2009) S. Gallorini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type I Streptococcus pneumoniae carbohydrate utilizes a nitric oxide and MHC II-dependent pathway for antigen presentation

(2008) Christopher D. Velez et al.   IMMUNOLOGY

Bacterial Polysaccharides with Zwitterionic Charge Motifs: Toll-Like Receptor 2 Agonists,T Cell Antigens, or Both?

(2008) Andreas Wack et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Identification of the Smallest Structure Capable of Evoking Opsonophagocytic Antibodies against Streptococcus pneumoniae Type 14

(2008) D. Safari et al.   INFECTION AND IMMUNITY

A New Model of Pneumococcal Lipoteichoic Acid Structure Resolves Biochemical, Biosynthetic, and Serologic Inconsistencies of the Current Model

(2008) H. S. Seo et al.   JOURNAL OF BACTERIOLOGY

Stereocontrolled Synthesis ofd- andl-β-Rhamnopyranosides with 4-O-6-S-α-Cyanobenzylidene-Protected 6-Thiorhamnopyranosyl Thioglycosides

(2008) David Crich et al.   JOURNAL OF ORGANIC CHEMISTRY

A microbial symbiosis factor prevents intestinal inflammatory disease

(2008) Sarkis K. Mazmanian et al.   NATURE

Role of glycan synthesis in colonization of the mammalian gut by the bacterial symbiont Bacteroides fragilis

(2008) M. J. Coyne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of surface architecture by symbiotic bacteria mediates host colonization

(2008) C. H. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Saccharide/protein conjugate vaccines for Bordetella species: Preparation of saccharide, development of new conjugation procedures, and physico-chemical and immunological characterization of the conjugates

(2008) Joanna Kubler-Kielb et al.   VACCINE