Chemical synthesis of the outer core oligosaccharide of Escherichia coli R3 and immunological evaluation

Total Synthesis of Anticoagulant Pentasaccharide Fondaparinux

(2014) Tiehai Li et al.   ChemMedChem

Glycoconjugate Vaccine Containing Escherichia coli O157:H7 O-Antigen Linked with Maltose-Binding Protein Elicits Humoral and Cellular Responses

(2014) Zhongrui Ma et al.   PLoS One

Immunoactivity of Protein Conjugates of Carba Analogues from Neisseria meningitidis A Capsular Polysaccharide

(2013) Qi Gao et al.   ACS Chemical Biology

The role of lipopolysaccharide-binding protein in innate immunity: a revisit and its relevance to oral/periodontal health

(2013) P.-H. Ding et al.   JOURNAL OF PERIODONTAL RESEARCH

Diversity-oriented Synthesis of Inner Core Oligosaccharides of the Lipopolysaccharide of Pathogenic Gram-negative Bacteria

(2013) You Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Immunological Evaluation of a Synthetic Clostridium difficile Oligosaccharide Conjugate Vaccine Candidate and Identification of a Minimal Epitope

(2013) Christopher E. Martin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of a well-defined glycoconjugate vaccine by a tyrosine-selective conjugation strategy

(2013) Qi-Ying Hu et al.   Chemical Science

Design of a Candida albicans Disaccharide Conjugate Vaccine by Reverse Engineering a Protective Monoclonal Antibody

(2012) David R. Bundle et al.   ACS Chemical Biology

Phosphorylation of the Synthetic Hexasaccharide Repeating Unit Is Essential for the Induction of Antibodies to Clostridium difficile PSII Cell Wall Polysaccharide

(2012) Roberto Adamo et al.   ACS Chemical Biology

Chemical Synthesis and Immunological Evaluation of the Inner Core Oligosaccharide of Francisella tularensis

(2012) Thomas J. Boltje et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lipopolysaccharide as a target for brucellosis vaccine design

(2012) Raquel Conde-Álvarez et al.   MICROBIAL PATHOGENESIS

Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197

(2012) E. Malito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Typical Preparation ofFrancisella tularensisO-Antigen Yields a Mixture of Three Types of Saccharides

(2011) Qi Wang et al.   BIOCHEMISTRY

A Possible Oligosaccharide-Conjugate Vaccine Candidate for Clostridium difficile Is Antigenic and Immunogenic

(2011) Matthias A. Oberli et al.   CHEMISTRY & BIOLOGY

Systematic Synthesis of Inhibitors of the Two First Enzymes of the Bacterial Heptose Biosynthetic Pathway: Towards Antivirulence Molecules Targeting Lipopolysaccharide Biosynthesis

(2011) Maxime Durka et al.   CHEMISTRY-A EUROPEAN JOURNAL

Defining Function of Lipopolysaccharide O-antigen Ligase WaaL Using Chemoenzymatically Synthesized Substrates

(2011) Weiqing Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis of Laminarin Fragments and Evaluation of a β-(1,3) Glucan Hexasaccaride-CRM197Conjugate as Vaccine Candidate againstCandida albicans

(2011) Roberto Adamo et al.   JOURNAL OF CARBOHYDRATE CHEMISTRY

Total synthesis of the core tetrasaccharide of Neisseria meningitidislipopolysaccharide, a potential vaccine candidate for meningococcal diseases

(2011) You Yang et al.   Chemical Science

l-Rhamnose Antigen: A Promising Alternative to α-Gal for Cancer Immunotherapies

(2010) Wenlan Chen et al.   ACS Chemical Biology

Theoretical Investigation of Solvent Effects on Glycosylation Reactions: Stereoselectivity Controlled by Preferential Conformations of the Intermediate Oxacarbenium-Counterion Complex

(2010) Hiroko Satoh et al.   Journal of Chemical Theory and Computation

In vitro bacterial polysaccharide biosynthesis: defining the functions of Wzy and Wzz

(2010) Robert Woodward et al.   Nature Chemical Biology

Overview of the development and current use of CRM197 conjugate vaccines for pediatric use

(2010) Henry R. Shinefield   VACCINE

Carbohydrates: A Frontier in Medicinal Chemistry

(2009) Pierre Stallforth et al.   JOURNAL OF MEDICINAL CHEMISTRY

Modular Synthesis of Heparan Sulfate Oligosaccharides for Structure−Activity Relationship Studies

(2009) Sailaja Arungundram et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research

(2009) Thomas J. Boltje et al.   Nature Chemistry

Synthesis, molecular dynamics simulations, and biology of a carba-analogue of the trisaccharide repeating unit of Streptococcus pneumoniae 19F capsular polysaccharide

(2009) Laura Legnani et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Identification of the Smallest Structure Capable of Evoking Opsonophagocytic Antibodies against Streptococcus pneumoniae Type 14

(2008) D. Safari et al.   INFECTION AND IMMUNITY

Efficient Synthesis of a Sialic Acid α(2→3)Galactose Building Block and Its Application to the Synthesis of Ganglioside GM3

(2008) Yunpeng Liu et al.   JOURNAL OF ORGANIC CHEMISTRY