Baicalein exerts neuroprotective effect against ischaemic/reperfusion injury via alteration of NF-kB and LOX and AMPK/Nrf2 pathway

Nano-curcumin simultaneously protects the blood-brain barrier and reduces M1-microglial activation during cerebral ischemia-reperfusion injury

(2019) Ye Wang et al.   ACS Applied Materials & Interfaces

Ganglioside GM1 protects against high altitude cerebral edema in rats by suppressing the oxidative stress and inflammatory response via the PI3K/AKT-Nrf2 pathway

(2018) Gu Gong et al.   MOLECULAR IMMUNOLOGY

Tissue kallikrein protects against ischemic stroke by suppressing TLR4/NF-κB and activating Nrf2 signaling pathway in rats

(2017) Jiawei Yang et al.   Experimental and Therapeutic Medicine

MAPK pathway mediates the anti‑oxidative effect of chicoric acid against cerebral ischemia‑reperfusion injury in�vivo

(2017) Linwei Jia et al.   Experimental and Therapeutic Medicine

Hexahydrocurcumin protects against cerebral ischemia/reperfusion injury, attenuates inflammation, and improves antioxidant defenses in a rat stroke model

(2017) Piyawadee Wicha et al.   PLoS One

Neuroprotection of Osthole against Cerebral Ischemia/Reperfusion Injury through an Anti-apoptotic Pathway in Rats

(2016) Kang Li et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Salvianolic acid A alleviates ischemic brain injury through the inhibition of inflammation and apoptosis and the promotion of neurogenesis in mice

(2016) Mei-Yin Chien et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protective effect of Naoxintong against cerebral ischemia reperfusion injury in mice

(2016) Jing Xue et al.   JOURNAL OF ETHNOPHARMACOLOGY

Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation

(2016) Lisha Zhao et al.   MOLECULES

A novel nuclear factor erythroid 2-related factor 2 (Nrf2) activator RS9 attenuates brain injury after ischemia reperfusion in mice

(2016) Keita Yamauchi et al.   NEUROSCIENCE

Pinocembrin attenuates hippocampal inflammation, oxidative perturbations and apoptosis in a rat model of global cerebral ischemia reperfusion

(2015) Muhammed A. Saad et al.   Pharmacological Reports

Chrysin Protects against Focal Cerebral Ischemia/Reperfusion Injury in Mice through Attenuation of Oxidative Stress and Inflammation

(2014) Yang Yao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Curcumin Protects Neuron against Cerebral Ischemia-Induced Inflammation through Improving PPAR-Gamma Function

(2013) Zun-Jing Liu et al.   Evidence-based Complementary and Alternative Medicine

Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood–brain barrier disruption and neurological deficits in stroke

(2013) Alessio Alfieri et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia–reperfusion injury through suppression of apoptosis and inflammation

(2013) Shuai Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Novel antiviral activity of baicalein against dengue virus

(2012) Keivan Zandi et al.   BMC Complementary and Alternative Medicine

Piperine suppresses cerebral ischemia–reperfusion-induced inflammation through the repression of COX-2, NOS-2, and NF-κB in middle cerebral artery occlusion rat model

(2012) Kumar Vaibhav et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Oxidative Stress and Antioxidant Defense

(2012) Esra Birben et al.   World Allergy Organization Journal

Baicalein loaded in tocol nanostructured lipid carriers (tocol NLCs) for enhanced stability and brain targeting

(2011) Ming-Jun Tsai et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

(2011) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Prodigiosin inhibits gp91phox and iNOS expression to protect mice against the oxidative/nitrosative brain injury induced by hypoxia–ischemia

(2011) Chia-Che Chang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia

(2010) Costantino Iadecola   ACTA NEUROPATHOLOGICA

Baicalin attenuates focal cerebral ischemic reperfusion injury through inhibition of nuclear factor κB p65 activation

(2010) Xia Xue et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Linking oxidative stress to inflammation: Toll-like receptors

(2010) Roop Gill et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

(2010) Rong Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neuroprotection by baicalein in ischemic brain injury involves PTEN/AKT pathway

(2009) Chao Liu et al.   JOURNAL OF NEUROCHEMISTRY

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

Ferulic acid provides neuroprotection against oxidative stress-related apoptosis after cerebral ischemia/reperfusion injury by inhibiting ICAM-1 mRNA expression in rats

(2008) Chin-Yi Cheng et al.   BRAIN RESEARCH

The flavonoid baicalin counteracts ischemic and oxidative insults to retinal cells and lipid peroxidation to brain membranes

(2008) S.H. Jung et al.   NEUROCHEMISTRY INTERNATIONAL