The Biogenesis, Biology, and Clinical Significance of Exosomal PD-L1 in Cancer
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Biogenesis, Biology, and Clinical Significance of Exosomal PD-L1 in Cancer
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-04-07
DOI
10.3389/fimmu.2020.00604
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Tumor mutational load predicts survival after immunotherapy across multiple cancer types
- (2019) Robert M. Samstein et al. NATURE GENETICS
- Assessment of Blood Tumor Mutational Burden as a Potential Biomarker for Immunotherapy in Patients With Non–Small Cell Lung Cancer With Use of a Next-Generation Sequencing Cancer Gene Panel
- (2019) Zhijie Wang et al. JAMA Oncology
- Exosomal PD-L1 Retains Immunosuppressive Activity and is Associated with Gastric Cancer Prognosis
- (2019) Yibo Fan et al. ANNALS OF SURGICAL ONCOLOGY
- Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory
- (2019) Mauro Poggio et al. CELL
- ALIX increases protein content and protective function of iPSC-derived exosomes
- (2019) Ruiting Sun et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Long non-coding RNA HOTAIR promotes exosome secretion by regulating RAB35 and SNAP23 in hepatocellular carcinoma
- (2019) Liang Yang et al. Molecular Cancer
- Comparison of Biomarker Modalities for Predicting Response to PD-1/PD-L1 Checkpoint Blockade
- (2019) Steve Lu et al. JAMA Oncology
- Circulating Tumor Cell PD-L1 Expression as Biomarker for Therapeutic Efficacy of Immune Checkpoint Inhibition in NSCLC
- (2019) Kloten et al. Cells
- Exosomal PD-L1 promotes tumor growth through immune escape in non-small cell lung cancer
- (2019) Dong Ha Kim et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Nivolumab versus docetaxel in previously treated advanced non-small-cell lung cancer (CheckMate 017 and CheckMate 057): 3-year update and outcomes in patients with liver metastases
- (2018) E E Vokes et al. ANNALS OF ONCOLOGY
- Exosome biogenesis, bioactivities and functions as new delivery systems of natural compounds
- (2018) Ammad Ahmad Farooqi et al. BIOTECHNOLOGY ADVANCES
- PD-L1 mRNA expression in plasma-derived exosomes is associated with response to anti-PD-1 antibodies in melanoma and NSCLC
- (2018) Marzia Del Re et al. BRITISH JOURNAL OF CANCER
- Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth
- (2018) Yi Yang et al. CELL RESEARCH
- Separation of plasma-derived exosomes into CD3(+) and CD3(-) fractions allows for association of immune cell and tumour cell markers with disease activity in HNSCC patients
- (2018) M.-N. Theodoraki et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Regulation and Function of the PD-L1 Checkpoint
- (2018) Chong Sun et al. IMMUNITY
- A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4
- (2018) Scott W. Messenger et al. JOURNAL OF CELL BIOLOGY
- PD-L1 Expression Heterogeneity in Non–Small Cell Lung Cancer: Defining Criteria for Harmonization between Biopsy Specimens and Whole Sections
- (2018) Enrico Munari et al. Journal of Thoracic Oncology
- miR-34c-5p promotes eradication of acute myeloid leukemia stem cells by inducing senescence through selective RAB27B targeting to inhibit exosome shedding
- (2018) Danyue Peng et al. LEUKEMIA
- Extracellular vesicles in cancer — implications for future improvements in cancer care
- (2018) Rong Xu et al. Nature Reviews Clinical Oncology
- Shedding light on the cell biology of extracellular vesicles
- (2018) Guillaume van Niel et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Biogenesis and function of extracellular vesicles in cancer
- (2018) Maarten P. Bebelman et al. PHARMACOLOGY & THERAPEUTICS
- Clinical significance of soluble programmed cell death ligand-1 (sPD-L1) in hepatocellular carcinoma patients treated with radiotherapy
- (2018) Hyun Ju Kim et al. RADIOTHERAPY AND ONCOLOGY
- Biogenesis and function of ESCRT-dependent extracellular vesicles
- (2018) Thomas Juan et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Manufacturing Exosomes: A Promising Therapeutic Platform
- (2018) Ivano Luigi Colao et al. TRENDS IN MOLECULAR MEDICINE
- Interferon γ and Its Important Roles in Promoting and Inhibiting Spontaneous and Therapeutic Cancer Immunity
- (2018) Elise Alspach et al. Cold Spring Harbor Perspectives in Biology
- Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
- (2018) Eva Maria Wenzel et al. Nature Communications
- ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation
- (2018) James Monypenny et al. Cell Reports
- Dynamic change of PD-L1 expression on circulating tumor cells in advanced solid tumor patients undergoing PD-1 blockade therapy
- (2018) Chunyan Yue et al. OncoImmunology
- Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer
- (2018) Charles S. Fuchs et al. JAMA Oncology
- Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles
- (2018) Franz L. Ricklefs et al. Science Advances
- Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
- (2018) Gang Chen et al. NATURE
- Targeting Programmed Cell Death -1 (PD-1) and Ligand (PD-L1): A new era in cancer active immunotherapy
- (2018) Anastasia Constantinidou et al. PHARMACOLOGY & THERAPEUTICS
- T-Cell–Inflamed Gene-Expression Profile, Programmed Death Ligand 1 Expression, and Tumor Mutational Burden Predict Efficacy in Patients Treated With Pembrolizumab Across 20 Cancers: KEYNOTE-028
- (2018) Patrick A. Ott et al. JOURNAL OF CLINICAL ONCOLOGY
- Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial
- (2018) Frank Stephen Hodi et al. LANCET ONCOLOGY
- Pan-tumor genomic biomarkers for PD-1 checkpoint blockade–based immunotherapy
- (2018) Razvan Cristescu et al. SCIENCE
- Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels
- (2018) David Novo et al. Nature Communications
- IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade
- (2017) Mark Ayers et al. JOURNAL OF CLINICAL INVESTIGATION
- Clinical applications of PD-L1 bioassays for cancer immunotherapy
- (2017) Delong Liu et al. Journal of Hematology & Oncology
- First-line pembrolizumab in cisplatin-ineligible patients with locally advanced and unresectable or metastatic urothelial cancer (KEYNOTE-052): a multicentre, single-arm, phase 2 study
- (2017) Arjun V Balar et al. LANCET ONCOLOGY
- T-cell invigoration to tumour burden ratio associated with anti-PD-1 response
- (2017) Alexander C. Huang et al. NATURE
- Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma
- (2017) Jedd D. Wolchok et al. NEW ENGLAND JOURNAL OF MEDICINE
- T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition
- (2017) Enfu Hui et al. SCIENCE
- BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1
- (2017) Simon J. Hogg et al. Cell Reports
- Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
- (2017) Angel Garcia-Diaz et al. Cell Reports
- Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
- (2017) Zachary R. Chalmers et al. Genome Medicine
- The Dynamic and Transient Immune Microenvironment in Locally Advanced Esophageal Adenocarcinoma Post Chemoradiation
- (2017) Ronan J. Kelly et al. ANNALS OF SURGERY
- PD-L1 expression on neoplastic or stromal cells is respectively a poor or good prognostic factor for adult T-cell leukemia/lymphoma
- (2016) H. Miyoshi et al. BLOOD
- Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma
- (2016) Antoni Ribas et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis
- (2016) Hao Gu et al. JOURNAL OF CLINICAL INVESTIGATION
- Nivolumab monotherapy in recurrent metastatic urothelial carcinoma (CheckMate 032): a multicentre, open-label, two-stage, multi-arm, phase 1/2 trial
- (2016) Padmanee Sharma et al. LANCET ONCOLOGY
- Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial
- (2016) F Stephen Hodi et al. LANCET ONCOLOGY
- ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins
- (2016) Carolina Villarroya-Beltri et al. Nature Communications
- Syntenin and syndecan in the biogenesis of exosomes
- (2015) Véronique Friand et al. BIOLOGY OF THE CELL
- Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
- (2015) Suzanne L. Topalian et al. CANCER CELL
- Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
- (2015) Padmanee Sharma et al. CELL
- Heparanase activates the syndecan-syntenin-ALIX exosome pathway
- (2015) Bart Roucourt et al. CELL RESEARCH
- Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer
- (2015) Hossein Borghaei et al. NEW ENGLAND JOURNAL OF MEDICINE
- The prognostic significance of PD-L1 in bladder cancer
- (2015) YIDE HUANG et al. ONCOLOGY REPORTS
- Neoantigens in cancer immunotherapy
- (2015) T. N. Schumacher et al. SCIENCE
- Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
- (2015) N. A. Rizvi et al. SCIENCE
- Cancer and the Immune System: Basic Concepts and Targets for Intervention
- (2015) Drew Pardoll SEMINARS IN ONCOLOGY
- Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
- (2014) Marina Colombo et al. Annual Review of Cell and Developmental Biology
- Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
- (2014) Matthew M. Gubin et al. NATURE
- Rab Proteins and the Compartmentalization of the Endosomal System
- (2014) A. Wandinger-Ness et al. Cold Spring Harbor Perspectives in Biology
- Gliomas Promote Immunosuppression through Induction of B7-H1 Expression in Tumor-Associated Macrophages
- (2013) O. Bloch et al. CLINICAL CANCER RESEARCH
- Heparanase Regulates Secretion, Composition, and Function of Tumor Cell-derived Exosomes
- (2013) Camilla A. Thompson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles
- (2013) Marina Colombo et al. JOURNAL OF CELL SCIENCE
- Molecular Mechanisms of the Membrane Sculpting ESCRT Pathway
- (2013) W. M. Henne et al. Cold Spring Harbor Perspectives in Biology
- Signaling Pathways in Exosomes Biogenesis, Secretion and Fate
- (2013) Lorena Urbanelli et al. Genes
- Syndecan–syntenin–ALIX regulates the biogenesis of exosomes
- (2012) Maria Francesca Baietti et al. NATURE CELL BIOLOGY
- Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells
- (2010) Nobuyoshi Kosaka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates
- (2010) Julie R. Brahmer et al. JOURNAL OF CLINICAL ONCOLOGY
- Exosomes: Extracellular organelles important in intercellular communication
- (2010) Suresh Mathivanan et al. Journal of Proteomics
- Cellular Internalization of Exosomes Occurs Through Phagocytosis
- (2010) Du Feng et al. TRAFFIC
- Rab27a and Rab27b control different steps of the exosome secretion pathway
- (2009) Matias Ostrowski et al. NATURE CELL BIOLOGY
- Rab GTPases as coordinators of vesicle traffic
- (2009) Harald Stenmark NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Pathways and mechanisms of endocytic recycling
- (2009) Barth D. Grant et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells
- (2008) J. Klibi et al. BLOOD
- Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
- (2008) K. Trajkovic et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now