Comparison of diclofenac with apigenin-glycosides rich Clinacanthus nutans extract for amending inflammation and catabolic protease regulations in osteoporotic-osteoarthritis rat model

Vitexin alleviates interleukin‐1β‐induced inflammatory responses in chondrocytes from osteoarthritis patients: Involvement of HIF‐1α pathway

(2019) Hongpeng Yang et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

A Comprehensive Review on Phytochemistry and Pharmacological Activities of Clinacanthus nutans (Burm.f.) Lindau

(2018) Leng Wei Khoo et al.   Evidence-based Complementary and Alternative Medicine

Vitexin alleviates ER-stress-activated apoptosis and the related inflammation in chondrocytes and inhibits the degeneration of cartilage in rats

(2018) Cheng-Long Xie et al.   Food & Function

Schaftoside ameliorates oxygen glucose deprivation-induced inflammation associated with the TLR4/Myd88/Drp1-related mitochondrial fission in BV2 microglia cells

(2018) Kecheng Zhou et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Clinacanthus nutans: a review on ethnomedicinal uses, chemical constituents and pharmacological properties

(2017) Ihsan N. Zulkipli et al.   PHARMACEUTICAL BIOLOGY

Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes

(2016) Jin Sung Park et al.   Biomolecules & Therapeutics

Anti-inflammatory effects of Viola yedoensis and the application of cell extraction methods for investigating bioactive constituents in macrophages

(2016) Yun Hee Jeong et al.   BMC Complementary and Alternative Medicine

Recent advances in the understanding of molecular mechanisms of cartilage degeneration, synovitis and subchondral bone changes in osteoarthritis

(2016) Yingliang Wei et al.   CONNECTIVE TISSUE RESEARCH

Mutagenicity and preclinical safety assessment of the aqueous extract ofClinacanthus nutansleaves

(2016) Elham Farsi et al.   DRUG AND CHEMICAL TOXICOLOGY

Methanolic Extract ofClinacanthus nutansExerts Antinociceptive Activity via the Opioid/Nitric Oxide-Mediated, but cGMP-Independent, Pathways

(2016) Mohammad Hafiz Abdul Rahim et al.   Evidence-based Complementary and Alternative Medicine

Ageing and the pathogenesis of osteoarthritis

(2016) Richard F. Loeser et al.   Nature Reviews Rheumatology

Prevalence of osteoporosis in patients awaiting total hip arthroplasty

(2015) Vitor Rodrigues Domingues et al.   Acta Ortopedica Brasileira

A look behind the scenes: the risk and pathogenesis of primary osteoporosis

(2015) Gretl Hendrickx et al.   Nature Reviews Rheumatology

Standardized extract of Ficus deltoidea stimulates insulin secretion and blocks hepatic glucose production by regulating the expression of glucose-metabolic genes in streptozitocin-induced diabetic rats

(2014) Elham Farsi et al.   BMC Complementary and Alternative Medicine

Apigenin inhibits osteoblastogenesis and osteoclastogenesis and prevents bone loss in ovariectomized mice

(2014) Tadashi Goto et al.   CYTOTECHNOLOGY

Antidiabetic Effects ofCarassius auratusComplex Formula in High Fat Diet Combined Streptozotocin-Induced Diabetic Mice

(2014) Zhi-Hong Wang et al.   Evidence-based Complementary and Alternative Medicine

Bone mineral density and association of osteoarthritis with fracture risk

(2014) M.Y. Chan et al.   OSTEOARTHRITIS AND CARTILAGE

PINP as a biological response marker during teriparatide treatment for osteoporosis

(2014) J. H. Krege et al.   OSTEOPOROSIS INTERNATIONAL

Analysis of FlavoneC-Glycosides in the Leaves ofClinacanthus nutans(Burm. f.) Lindau by HPTLC and HPLC-UV/DAD

(2014) June Lee Chelyn et al.   TheScientificWorldJOURNAL

Value of biomarkers in osteoarthritis: current status and perspectives

(2013) M Lotz et al.   ANNALS OF THE RHEUMATIC DISEASES

Genotoxicity and acute and subchronic toxicity studies of a standardized methanolic extract of Ficus deltoidea leaves

(2013) E Farsi et al.   Clinics

NSAIDs and fracture healing

(2013) Piet Geusens et al.   CURRENT OPINION IN RHEUMATOLOGY

The NF-κB signalling pathway in osteoarthritis

(2013) Stella Rigoglou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Vitexin Inhibits Inflammatory Pain in Mice by Targeting TRPV1, Oxidative Stress, and Cytokines

(2013) Sergio M. Borghi et al.   JOURNAL OF NATURAL PRODUCTS

Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials

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Homeostatic Mechanisms in Articular Cartilage and Role of Inflammation in Osteoarthritis

(2013) Xavier Houard et al.   Current Rheumatology Reports

Is knee osteoarthritis a symmetrical disease? Analysis of a 12 year prospective cohort study

(2012) Andrew J Metcalfe et al.   BMC MUSCULOSKELETAL DISORDERS

Bone remodelling in osteoarthritis

(2012) David B. Burr et al.   Nature Reviews Rheumatology

Arthritis Increases the Risk for Fractures -- Results from the Women's Health Initiative

(2011) N. C. WRIGHT et al.   JOURNAL OF RHEUMATOLOGY

NF-κB Signaling: Multiple Angles to Target OA

(2010) Kenneth B. Marcu et al.   CURRENT DRUG TARGETS

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

AVR/NAVR deficiency lowers blood pressure and differentially affects urinary concentrating ability, cognition, and anxiety-like behavior in male and female mice

(2010) Victoria L. M. Herrera et al.   PHYSIOLOGICAL GENOMICS

Inhibition of osteoblastic bone formation by nuclear factor-κB

(2009) Jia Chang et al.   NATURE MEDICINE

Proinflammatory cytokines and osteoporosis

(2009) Robert R. McLean   Current Osteoporosis Reports