A Systems Biology Approach Identifies Hidden Regulatory Connections Between the Circadian and Cell-Cycle Checkpoints

Systems approach reveals photosensitivity and PER 2 level as determinants of clock‐modulator efficacy

(2019) Dae Wook Kim et al.   Molecular Systems Biology

CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch

(2018) Rajesh Narasimamurthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Cogs: Interplay between Circadian Clock and Cell Cycle

(2018) Jonathan Gaucher et al.   TRENDS IN CELL BIOLOGY

Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein and ubiquitin ligase MDM2

(2018) JingJing Liu et al.   Science Signaling

Design Principles of Phosphorylation-Dependent Timekeeping in Eukaryotic Circadian Clocks

(2017) Koji L. Ode et al.   Cold Spring Harbor Perspectives in Biology

Protein sequestration versus Hill-type repression in circadian clock models

(2016) Jae Kyoung Kim   IET Systems Biology

CRY2 and FBXL3 Cooperatively Degrade c-MYC

(2016) Anne-Laure Huber et al.   MOLECULAR CELL

Intercellular Coupling of the Cell Cycle and Circadian Clock in Adult Stem Cell Culture

(2016) Toru Matsu-ura et al.   MOLECULAR CELL

Transcriptional architecture of the mammalian circadian clock

(2016) Joseph S. Takahashi   NATURE REVIEWS GENETICS

Model-driven experimental approach reveals the complex regulatory distribution of p53 by the circadian factor Period 2

(2016) Tetsuya Gotoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Timeless Link Between Circadian Patterns and Disease

(2016) Gianluigi Mazzoccoli et al.   TRENDS IN MOLECULAR MEDICINE

Association of the circadian factor Period 2 to p53 influences p53's function in DNA-damage signaling

(2015) Tetsuya Gotoh et al.   MOLECULAR BIOLOGY OF THE CELL

A Period2 Phosphoswitch Regulates and Temperature Compensates Circadian Period

(2015) Min Zhou et al.   MOLECULAR CELL

A tunable artificial circadian clock in clock-defective mice

(2015) Matthew D’Alessandro et al.   Nature Communications

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization

(2015) Stephanie J Papp et al.   eLife

The Validity of Quasi-Steady-State Approximations in Discrete Stochastic Simulations

(2014) Jae Kyoung Kim et al.   BIOPHYSICAL JOURNAL

The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cells

(2014) Tetsuya Gotoh et al.   MOLECULAR BIOLOGY OF THE CELL

Circadian rhythms synchronize mitosis in Neurospora crassa

(2014) C. I. Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p53 regulates Period2 expression and the circadian clock

(2013) Takao Miki et al.   Nature Communications

Light Acts on the Zebrafish Circadian Clock to Suppress Rhythmic Mitosis and Cell Proliferation

(2012) T. Katherine Tamai et al.   JOURNAL OF BIOLOGICAL RHYTHMS

A mechanism for robust circadian timekeeping via stoichiometric balance

(2012) Jae Kyoung Kim et al.   Molecular Systems Biology

NONO couples the circadian clock to the cell cycle

(2012) E. Kowalska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

NEMO/NLK Phosphorylates PERIOD to Initiate a Time-Delay Phosphorylation Circuit that Sets Circadian Clock Speed

(2011) Joanna C. Chiu et al.   CELL

Mammalian cryptochromes impinge on cell cycle progression in a circadian clock-independent manner

(2011) Eugin Destici et al.   CELL CYCLE

Kinases and phosphatases in the mammalian circadian clock

(2011) Silke Reischl et al.   FEBS LETTERS

Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening

(2011) Z. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1

(2011) H.-m. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

(2010) Q.-J. Meng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Gating of the Cell Cycle Revealed in Single Cyanobacterial Cells

(2010) Q. Yang et al.   SCIENCE

A Genome-wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells

(2009) Eric E. Zhang et al.   CELL

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-α3 binding

(2009) N D Marchenko et al.   CELL DEATH AND DIFFERENTIATION

Selective Inhibition of Casein Kinase 1  Minimally Alters Circadian Clock Period

(2009) K. M. Walton et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Involvement of the Protein Kinase CK2 in the Regulation of Mammalian Circadian Rhythms

(2009) Y. Tsuchiya et al.   Science Signaling

The Role of β-TrCP1 and β-TrCP2 in Circadian Rhythm Generation by Mediating Degradation of Clock Protein PER2

(2008) Kanae Ohsaki et al.   JOURNAL OF BIOCHEMISTRY

A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3 

(2008) T. Hirota et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA