Downregulation of eEF1A/EFT3-4 Enhances Dopaminergic Neurodegeneration After 6-OHDA Exposure in C. elegans Model

Utility of Neuronal-Derived Exosomes to Examine Molecular Mechanisms That Affect Motor Function in Patients With Parkinson Disease

(2019) Dilan Athauda et al.   JAMA Neurology

Molecular targets for modulating the protein translation vital to proteostasis and neuron degeneration in Parkinson’s disease

(2019) Zhi Dong Zhou et al.   Translational Neurodegeneration

Neurotoxin-Induced Animal Models of Parkinson Disease: Pathogenic Mechanism and Assessment

(2018) Xian-Si Zeng et al.   ASN Neuro

6-OHDA-induced dopaminergic neurodegeneration in Caenorhabditis elegans is promoted by the engulfment pathway and inhibited by the transthyretin-related protein TTR-33

(2018) Sarah-Lena Offenburger et al.   PLoS Genetics

Mesencephalic astrocyte-derived neurotrophic factor alleviated 6-OHDA-induced cell damage via ROS-AMPK/mTOR mediated autophagic inhibition

(2017) Jingxing Zhang et al.   EXPERIMENTAL GERONTOLOGY

Holothuria scabra extracts exhibit anti-Parkinson potential in C. elegans: A model for anti-Parkinson testing

(2017) Pawanrat Chalorak et al.   NUTRITIONAL NEUROSCIENCE

Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models

(2017) Malabika Maulik et al.   Frontiers in Genetics

Biallelic mutations in the gene encoding eEF1A2 cause seizures and sudden death in F0 mice

(2017) Faith C. J. Davies et al.   Scientific Reports

Evaluation of rotigotine transdermal patch for the treatment of apathy and motor symptoms in Parkinson’s disease

(2016) Robert A Hauser et al.   BMC Neurology

Comparative mRNA Expression of eEF1A Isoforms and a PI3K/Akt/mTOR Pathway in a Cellular Model of Parkinson’s Disease

(2016) Kawinthra Khwanraj et al.   Parkinsons Disease

The 6-OHDA mouse model of Parkinson's disease – Terminal striatal lesions provide a superior measure of neuronal loss and replacement than median forebrain bundle lesions

(2015) V. Bagga et al.   BEHAVIOURAL BRAIN RESEARCH

Deregulation of protein translation control, a potential game-changing hypothesis for Parkinson's disease pathogenesis

(2015) Jean-Marc Taymans et al.   TRENDS IN MOLECULAR MEDICINE

Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson’s disease

(2015) Paula Garcia-Esparcia et al.   Acta Neuropathologica Communications

RTCB-1 Mediates Neuroprotection via XBP-1 mRNA Splicing in the Unfolded Protein Response Pathway

(2014) A. Ray et al.   JOURNAL OF NEUROSCIENCE

Proteomic analysis of human substantia nigra identifies novel candidates involved in Parkinson's disease pathogenesis

(2014) Virginie Licker et al.   PROTEOMICS

The translation elongation factor eEF1A1 couples transcription to translation during heat shock response

(2014) Maria Vera et al.   eLife

Rotigotine protects against glutamate toxicity in primary dopaminergic cell culture

(2013) Sandra Oster et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neuroprotective effect of brain-derived neurotrophic factor mediated by autophagy through the PI3K/Akt/mTOR pathway

(2013) AI CHEN et al.   Molecular Medicine Reports

Translation elongation factor-1A1 (eEF1A1) localizes to the spine by domain III

(2012) Sun-Jung Cho et al.   BMB Reports

Programmed cell death in C. elegans, mammals and plants

(2012) Christina E.N. Lord et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

An Overview of Stress Response and Hypometabolic Strategies in Caenorhabditis elegans: Conserved and Contrasting Signals with the Mammalian System

(2012) Benjamin Lant et al.   International Journal of Biological Sciences

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

(2012) Julie A. Moreno et al.   NATURE

Expression analysis of dopaminergic neurons in Parkinson’s disease and aging links transcriptional dysregulation of energy metabolism to cell death

(2011) Matthias Elstner et al.   ACTA NEUROPATHOLOGICA

Neurotoxin-based models of Parkinson's disease

(2011) J. Bové et al.   NEUROSCIENCE

Neurite Outgrowth Mediated by Translation Elongation Factor eEF1A1: A Target for Antiplatelet Agent Cilostazol

(2011) Kenji Hashimoto et al.   PLoS One

Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease

(2011) Calivarathan Latchoumycandane et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

C. elegansas a model organism to investigate molecular pathways involved with Parkinson's disease

(2010) Adam J. Harrington et al.   DEVELOPMENTAL DYNAMICS

Eef1a2 Promotes Cell Growth, Inhibits Apoptosis and Activates JAK/STAT and AKT Signaling in Mouse Plasmacytomas

(2010) Zhaoyang Li et al.   PLoS One

A review of Parkinson's disease

(2008) C. A. Davie   BRITISH MEDICAL BULLETIN