Hypoxia Inducible Factor-1α: The Curator of Gut Homeostasis

The Iron Tug-of-War between Bacterial Siderophores and Innate Immunity

(2019) Rachel Golonka et al.   Journal of Innate Immunity

Hypoxic environment promotes barrier formation in human intestinal epithelial cells through regulation of miRNA-320a expression

(2019) Stephanie Muenchau et al.   MOLECULAR AND CELLULAR BIOLOGY

Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism

(2019) José Luís Fachi et al.   Cell Reports

Age- and Sex-Dependent Patterns of Gut Microbial Diversity in Human Adults

(2019) Jacobo de la Cuesta-Zuluaga et al.   mSystems

Host Genetics, Diet, and Microbiome: The Role of AMY1

(2019) Sofía Morán-Ramos et al.   TRENDS IN MICROBIOLOGY

Epigenetic Regulation at the Interplay Between Gut Microbiota and Host Metabolism

(2019) Joan Miro-Blanch et al.   Frontiers in Genetics

Hypoxia-inducible factor 1α plays a predominantly negative role in regulatory T cell functions

(2018) Tzu-Sheng Hsu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Redox signaling mediated by the gut microbiota

(2017) Rheinallt M. Jones et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of Adenosine A3 Receptor Ameliorates TNF-Alpha-Induced Barrier Dysfunction in Human Intestinal Epithelial Cells

(2017) Tianhua Ren et al.   GASTROENTEROLOGY

The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets

(2017) Bertrand Allard et al.   IMMUNOLOGICAL REVIEWS

Adenosine A2A receptor signaling attenuates LPS-induced pro-inflammatory cytokine formation of mouse macrophages by inducing the expression of DUSP1

(2016) Krisztina Köröskényi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Oxygen metabolism and barrier regulation in the intestinal mucosa

(2016) Louise E. Glover et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting hypoxia-mediated mucin 2 production as a therapeutic strategy for mucinous tumors

(2016) Ashok K. Dilly et al.   Translational Research

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

THE GUT MICROBIOTA AND IMMUNE SYSTEM RELATIONSHIP IN HUMAN GRAFT-VERSUS-HOST DISEASE

(2016) Lucrezia Laterza et al.   Mediterranean Journal of Hematology and Infectious Diseases

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

(2015) Caleb J. Kelly et al.   Cell Host & Microbe

Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis

(2015) C M Aherne et al.   Mucosal Immunology

Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization

(2015) Di Fan et al.   NATURE MEDICINE

Regulatory T cell-mediated anti-inflammatory effects promote successful tissue repair in both indirect and direct manners

(2015) Hong Lei et al.   Frontiers in Pharmacology

Defining dysbiosis and its influence on host immunity and disease

(2014) Charisse Petersen et al.   CELLULAR MICROBIOLOGY

HIF-1α restricts NF-κB-dependent gene expression to control innate immunity signals

(2014) Daniel Bandarra et al.   Disease Models & Mechanisms

HIF Transcription Factors, Inflammation, and Immunity

(2014) Asis Palazon et al.   IMMUNITY

PHD Inhibition Mitigates and Protects Against Radiation-Induced Gastrointestinal Toxicity via HIF2

(2014) C. M. Taniguchi et al.   Science Translational Medicine

Architecture of tight junctions and principles of molecular composition

(2014) Christina M. Van Itallie et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Trefoil factors in inflammatory bowel disease

(2014) Luise Aamann   WORLD JOURNAL OF GASTROENTEROLOGY

Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors

(2014) Olga Sedlakova   Frontiers in Physiology

Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution

(2013) Jessica M. Holmén Larsson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Regulation of erythropoiesis by hypoxia-inducible factors

(2013) Volker H. Haase   BLOOD REVIEWS

Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent

(2013) Laura Wrzosek et al.   BMC BIOLOGY

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

HIF-independent role of prolyl hydroxylases in the cellular response to amino acids

(2012) R V Durán et al.   ONCOGENE

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Hypoxia and Metabolic Factors That Influence Inflammatory Bowel Disease Pathogenesis

(2011) Louise E. Glover et al.   GASTROENTEROLOGY

Hypoxia-Inducible Factor Signaling Provides Protection in Clostridium difficile-Induced Intestinal Injury

(2010) Simon A. Hirota et al.   GASTROENTEROLOGY

Increased Expression of Hypoxia-Inducible Factor 1α in Coeliac Disease

(2010) Ádám Vannay et al.   PEDIATRIC RESEARCH

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

(2009) David R. Mole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of hypoxia-inducible factor-1α by NF-κB

(2008) Patrick van Uden et al.   BIOCHEMICAL JOURNAL

Tumor necrosis factor α activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells

(2008) Yuki Kuwano et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis

(2007) Eoin P. Cummins et al.   GASTROENTEROLOGY