MicroRNAs in Systemic Lupus Erythematosus: a Perspective on the Path from Biological Discoveries to Clinical Practice

Novel paradigms in systemic lupus erythematosus

(2019) Thomas Dörner et al.   LANCET

MiR‐183 delivery attenuates murine lupus nephritis‐related injuries via targeting mTOR

(2019) Xiuzhen Li et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Dysregulation of microRNAs in autoimmune diseases: Pathogenesis, biomarkers and potential therapeutic targets

(2018) Hai Long et al.   CANCER LETTERS

Metazoan MicroRNAs

(2018) David P. Bartel   CELL

Downregulation of BDH2 modulates iron homeostasis and promotes DNA demethylation in CD4 + T cells of systemic lupus erythematosus

(2018) Ming Zhao et al.   CLINICAL IMMUNOLOGY

Associations of circulating cell-free microRNA with vasculopathy and vascular events in systemic lupus erythematosus patients

(2018) SD Kay et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Inhibition of microRNA-182-5p contributes to attenuation of lupus nephritis via Foxo1 signaling

(2018) Xiaoyang Wang et al.   EXPERIMENTAL CELL RESEARCH

Reduction of CD19 autoimmunity marker on B cells of paediatric SLE patients through repressing PU.1/TNF-α/BAFF axis pathway by miR-155

(2017) H. R. Aboelenein et al.   GROWTH FACTORS

miRNA-451a Targets IFN Regulatory Factor 8 for the Progression of Systemic Lupus Erythematosus

(2017) Jia Cheng et al.   INFLAMMATION

Enhanced expression of TREM-1 in splenic cDCs in lupus prone mice and it was modulated by miRNA-150

(2017) Sheng Gao et al.   MOLECULAR IMMUNOLOGY

Regulation of MiR-146a and TRAF6 in the Diagnose of Lupus Nephritis

(2017) Yunfeng Zhu et al.   MEDICAL SCIENCE MONITOR

MicroRNA 155-deficiency leads to decreased autoantibody levels and reduced severity of nephritis and pneumonitis in pristane-induced lupus

(2017) Harald Leiss et al.   PLoS One

miR-148a-3p overexpression contributes to glomerular cell proliferation by targeting PTEN in lupus nephritis

(2016) Liu Qingjuan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A polymorphism upstream MIR1279 gene is associated with pericarditis development in Systemic Lupus Erythematosus and contributes to definition of a genetic risk profile for this complication

(2016) C Ciccacci et al.   LUPUS

New insights into the immunopathogenesis of systemic lupus erythematosus

(2016) George C. Tsokos et al.   Nature Reviews Rheumatology

The effect of ethnicity and genetic ancestry on the epidemiology, clinical features and outcome of systemic lupus erythematosus

(2016) Myles J. Lewis et al.   RHEUMATOLOGY

The role of microRNA-31 and microRNA-21 as regulatory biomarkers in the activation of T lymphocytes of Egyptian lupus patients

(2016) Khalda Sayed Amr et al.   RHEUMATOLOGY INTERNATIONAL

In Vivo Therapeutic Success of MicroRNA-155 Antagomir in a Mouse Model of Lupus Alveolar Hemorrhage

(2016) Shiyu Zhou et al.   Arthritis & Rheumatology

MicroRNA-130b Ameliorates Murine Lupus Nephritis Through Targeting the Type I Interferon Pathway on Renal Mesangial Cells

(2016) Xiao Han et al.   Arthritis & Rheumatology

High-Throughput Sequencing Reveals Circulating miRNAs as Potential Biomarkers of Kidney Damage in Patients with Systemic Lupus Erythematosus

(2016) Elkin Navarro-Quiroz et al.   PLoS One

MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers

(2015) Isabelle Duroux-Richard et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

miRNAs in the Pathogenesis of Systemic Lupus Erythematosus

(2015) Bo Qu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNA as Biomarkers and Diagnostics

(2015) Jin Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

miR-155 Deficiency Ameliorates Autoimmune Inflammation of Systemic Lupus Erythematosus by TargetingS1pr1inFaslpr/lprMice

(2015) Qian Xin et al.   JOURNAL OF IMMUNOLOGY

Mycophenolic acid upregulates miR-142-3P/5P and miR-146a in lupus CD4+T cells

(2015) Q Tang et al.   LUPUS

miR-29c in urinary exosomes as predictor of early renal fibrosis in lupus nephritis

(2015) Cristina Solé et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis

(2015) Wen Pan et al.   Nature Communications

MicroRNA-146a regulates ICOS–ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres

(2015) Alvin Pratama et al.   Nature Communications

Type I Interferon Inhibition of MicroRNA-146a Maturation Through Up-Regulation of Monocyte Chemotactic Protein-Induced Protein 1 in Systemic Lupus Erythematosus

(2015) Bo Qu et al.   Arthritis & Rheumatology

DNA methylation and mRNA and microRNA expression of SLE CD4+ T cells correlate with disease phenotype

(2014) Ming Zhao et al.   JOURNAL OF AUTOIMMUNITY

Differential microRNA Profile and Post-Transcriptional Regulation Exist in Systemic Lupus Erythematosus Patients with Distinct Autoantibody Specificities

(2014) Sudhir Kumar Chauhan et al.   JOURNAL OF CLINICAL IMMUNOLOGY

microRNAs in Cardiovascular Diseases

(2014) Gianluigi Condorelli et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Systemic lupus erythematosus and lupus nephritis

(2014) Toli Koutsokeras et al.   NATURE REVIEWS DRUG DISCOVERY

A114: Methylprednisolone-Induced Inhibition of miR-155 Expression Increases SOCS1-Driven Suppression of Cytokine Signaling

(2014) Trevor E. Davis et al.   Arthritis & Rheumatology

Glucocorticoids Suppress T Cell Function by Up-Regulating MicroRNA-98

(2013) Trevor E. Davis et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-146a regulates survival and maturation of human plasmacytoid dendritic cells

(2013) J. J. Karrich et al.   BLOOD

miR-150 Promotes Renal Fibrosis in Lupus Nephritis by Downregulating SOCS1

(2013) H. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Deletion of microRNA-155 reduces autoantibody responses and alleviates lupus-like disease in the Faslpr mouse

(2013) T.-H. Thai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleic Acid Sensors and Type I Interferon Production in Systemic Lupus Erythematosus

(2013) Meena Shrivastav et al.   Frontiers in Immunology

Recent insights into the genetic basis of systemic lupus erythematosus

(2012) Ornella Josephine Rullo et al.   ANNALS OF THE RHEUMATIC DISEASES

Distinct roles of myeloid and plasmacytoid dendritic cells in systemic lupus erythematosus

(2012) Vera Sau-Fong Chan et al.   AUTOIMMUNITY REVIEWS

MS2 VLP-based delivery of microRNA-146a inhibits autoantibody production in lupus-prone mice

(2012) Yang Pan et al.   International Journal of Nanomedicine

The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α

(2012) Shu Zhu et al.   NATURE MEDICINE

Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression

(2011) E. Stagakis et al.   ANNALS OF THE RHEUMATIC DISEASES

Silencing of microRNA-21in vivoameliorates autoimmune splenomegaly in lupus mice

(2011) Barry G. Garchow et al.   EMBO Molecular Medicine

A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus

(2011) Xiaobing Luo et al.   PLoS Genetics

MicroRNA-125a contributes to elevated inflammatory chemokine RANTES levels via targeting KLF13 in systemic lupus erythematosus

(2010) Xia Zhao et al.   ARTHRITIS AND RHEUMATISM

The MicroRNA Spectrum in 12 Body Fluids

(2010) J. A. Weber et al.   CLINICAL CHEMISTRY

Inducible microRNA-155 Feedback Promotes Type I IFN Signaling in Antiviral Innate Immunity by Targeting Suppressor of Cytokine Signaling 1

(2010) P. Wang et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1

(2010) W. Pan et al.   JOURNAL OF IMMUNOLOGY

Dicer Insufficiency and MicroRNA-155 Overexpression in Lupus Regulatory T Cells: An Apparent Paradox in the Setting of an Inflammatory Milieu

(2010) A. A. Divekar et al.   JOURNAL OF IMMUNOLOGY

Identification of a Common Lupus Disease-Associated microRNA Expression Pattern in Three Different Murine Models of Lupus

(2010) Rujuan Dai et al.   PLoS One

MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

(2009) Yuanjia Tang et al.   ARTHRITIS AND RHEUMATISM

MicroRNA Control in the Immune System: Basic Principles

(2009) Changchun Xiao et al.   CELL

MicroRNA in autoimmunity and autoimmune diseases

(2009) Kaleb M. Pauley et al.   JOURNAL OF AUTOIMMUNITY

MicroRNA-146a Feedback Inhibits RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK2

(2009) J. Hou et al.   JOURNAL OF IMMUNOLOGY

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS