A Humanized Monoclonal Antibody Cocktail to Prevent Pulmonary Ricin Intoxication

Passive immunization with an extended half-life monoclonal antibody protects Rhesus macaques against aerosolized ricin toxin

(2020) Chad J. Roy et al.   npj Vaccines

Sensitivity of Kupffer cells and liver sinusoidal endothelial cells to ricin toxin and ricin toxin–Ab complexes

(2019) Bridget Mooney et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TNF Family Cytokines Induce Distinct Cell Death Modalities in the A549 Human Lung Epithelial Cell Line when Administered in Combination with Ricin Toxin

(2019) Hodges et al.   Toxins

An intranasally administered monoclonal antibody cocktail abrogates ricin toxin-induced pulmonary tissue damage and inflammation

(2019) Yinghui Rong et al.   Human Vaccines & Immunotherapeutics

ZMapp Reinforces the Airway Mucosal Barrier Against Ebola Virus

(2018) Bing Yang et al.   JOURNAL OF INFECTIOUS DISEASES

Beyond the Dirty Dozen: A Proposed Methodology for Assessing Future Bioweapon Threats

(2017) Theodore J Cieslak et al.   MILITARY MEDICINE

Spatial location of neutralizing and non-neutralizing B cell epitopes on domain 1 of ricin toxin’s binding subunit

(2017) Yinghui Rong et al.   PLoS One

Treatments for Pulmonary Ricin Intoxication: Current Aspects and Future Prospects

(2017) Yoav Gal et al.   Toxins

Humanized Monoclonal Antibody That Passively Protects Mice against Systemic and Intranasal Ricin Toxin Challenge

(2016) Greta Van Slyke et al.   Clinical and Vaccine Immunology

Development of a drug delivery system for efficient alveolar delivery of a neutralizing monoclonal antibody to treat pulmonary intoxication to ricin

(2016) Renaud Respaud et al.   JOURNAL OF CONTROLLED RELEASE

Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin’s Enzymatic Subunit Interfere with Intracellular Toxin Transport

(2016) Anastasiya Yermakova et al.   Scientific Reports

Isolation of Anti-Ricin Protective Antibodies Exhibiting High Affinity from Immunized Non-Human Primates

(2016) Tal Noy-Porat et al.   Toxins

Converting monoclonal antibody-based immunotherapies from passive to active: bringing immune complexes into play

(2016) Jennifer Lambour et al.   Emerging Microbes & Infections

Modeling the Oxidation of Methionine Residues by Peroxides in Proteins

(2015) Naresh Chennamsetty et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Diverse Profiles of Ricin-Cell Interactions in the Lung Following Intranasal Exposure to Ricin

(2015) Anita Sapoznikov et al.   Toxins

Clinical and Pathological Findings Associated with Aerosol Exposure of Macaques to Ricin Toxin

(2015) Seth Pincus et al.   Toxins

Chimeric Plantibody Passively Protects Mice against Aerosolized Ricin Challenge

(2014) Erin K. Sully et al.   Clinical and Vaccine Immunology

PEGylation of antibody fragments greatly increases their local residence time following delivery to the respiratory tract

(2014) Salome Juliette Koussoroplis et al.   JOURNAL OF CONTROLLED RELEASE

Fate of inhaled monoclonal antibodies after the deposition of aerosolized particles in the respiratory system

(2014) L. Guilleminault et al.   JOURNAL OF CONTROLLED RELEASE

Structure-Based Prediction of Asparagine and Aspartate Degradation Sites in Antibody Variable Regions

(2014) Jasmin F. Sydow et al.   PLoS One

Assessment of fully automated antibody homology modeling protocols in molecular operating environment

(2014) Johannes K. X. Maier et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Antibody-Mediated Inhibition of Ricin Toxin Retrograde Transport

(2014) A. Yermakova et al.   mBio

Stepwise Engineering of Heterodimeric Single Domain Camelid VHH Antibodies That Passively Protect Mice from Ricin Toxin

(2013) David J. Vance et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathology of Lethal and Sublethal Doses of Aerosolized Ricin in Rhesus Macaques

(2013) Manoj Bhaskaran et al.   TOXICOLOGIC PATHOLOGY

Conformation-Dependent High-Affinity Potent Ricin-Neutralizing Monoclonal Antibodies

(2012) Wei-Gang Hu et al.   Biomed Research International

Emerging antibody products and Nicotiana manufacturing

(2011) Kevin J. Whaley et al.   Human vaccines & immunotherapeutics

The Airways, a Novel Route for Delivering Monoclonal Antibodies to Treat Lung Tumors

(2011) Agnès Maillet et al.   PHARMACEUTICAL RESEARCH

Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB)

(2011) Anastasiya Yermakova et al.   VACCINE

Folding domains within the ricin toxin A subunit as targets of protective antibodies

(2010) Joanne M. O’Hara et al.   VACCINE

A Monoclonal Immunoglobulin G Antibody Directed against an Immunodominant Linear Epitope on the Ricin A Chain Confers Systemic and Mucosal Immunity to Ricin

(2009) L. M. Neal et al.   INFECTION AND IMMUNITY

Pulmonary Inflammation Triggered by Ricin Toxin Requires Macrophages and IL-1 Signaling

(2009) M. L. Lindauer et al.   JOURNAL OF IMMUNOLOGY