An intranasally administered monoclonal antibody cocktail abrogates ricin toxin-induced pulmonary tissue damage and inflammation

Deciphering the domain specificity of C. difficile toxin neutralizing antibodies

(2019) Leah E. Cole et al.   VACCINE

Sensitivity of Kupffer cells and liver sinusoidal endothelial cells to ricin toxin and ricin toxin–Ab complexes

(2019) Bridget Mooney et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TNF Family Cytokines Induce Distinct Cell Death Modalities in the A549 Human Lung Epithelial Cell Line when Administered in Combination with Ricin Toxin

(2019) Hodges et al.   Toxins

Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin

(2019) Natalia Sowa-Rogozińska et al.   Toxins

ZMapp Reinforces the Airway Mucosal Barrier Against Ebola Virus

(2018) Bing Yang et al.   JOURNAL OF INFECTIOUS DISEASES

Engineering therapeutic antibodies to combat infectious diseases

(2018) Ellen K Wagner et al.   Current Opinion in Chemical Engineering

Humanised monoclonal antibodies neutralise pertussis toxin by receptor blockade and reduced retrograde trafficking

(2018) Edith Acquaye-Seedah et al.   CELLULAR MICROBIOLOGY

Beyond the Dirty Dozen: A Proposed Methodology for Assessing Future Bioweapon Threats

(2017) Theodore J Cieslak et al.   MILITARY MEDICINE

Spatial location of neutralizing and non-neutralizing B cell epitopes on domain 1 of ricin toxin’s binding subunit

(2017) Yinghui Rong et al.   PLoS One

Extended therapeutic window for post-exposure treatment of ricin intoxication conferred by the use of high-affinity antibodies

(2017) Tal Noy-Porat et al.   TOXICON

Treatments for Pulmonary Ricin Intoxication: Current Aspects and Future Prospects

(2017) Yoav Gal et al.   Toxins

Humanized Monoclonal Antibody That Passively Protects Mice against Systemic and Intranasal Ricin Toxin Challenge

(2016) Greta Van Slyke et al.   Clinical and Vaccine Immunology

Progress and challenges associated with the development of ricin toxin subunit vaccines

(2016) David J. Vance et al.   Expert Review of Vaccines

Immortalized MH-S cells lack defining features of primary alveolar macrophages and do not support mouse pneumovirus replication

(2016) Todd A. Brenner et al.   IMMUNOLOGY LETTERS

Applications in Stimulated Emission Depletion Microscopy: Localization of a Protein Toxin in the Endoplasmic Reticulum Following Retrograde Transport

(2016) Cristina Herrera et al.   MICROSCOPY AND MICROANALYSIS

Quantitative profiling of the in vivo enzymatic activity of ricin reveals disparate depurination of different pulmonary cell types

(2016) Reut Falach et al.   TOXICOLOGY LETTERS

Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin’s Enzymatic Subunit Interfere with Intracellular Toxin Transport

(2016) Anastasiya Yermakova et al.   Scientific Reports

Lung inflammation caused by inhaled toxicants: a review

(2016) John Wong et al.   International Journal of Chronic Obstructive Pulmonary Disease

A Combination of Three Fully Human Toxin A- and Toxin B-Specific Monoclonal Antibodies Protects against Challenge with Highly Virulent Epidemic Strains of Clostridium difficile in the Hamster Model

(2015) Natalie G. Anosova et al.   Clinical and Vaccine Immunology

Mechanisms of Ricin Toxin Neutralization Revealed through Engineered Homodimeric and Heterodimeric Camelid Antibodies

(2015) Cristina Herrera et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ebola vaccine R&D: Filling the knowledge gaps

(2015) Donata Medaglini et al.   Science Translational Medicine

Antibody treatment against pulmonary exposure to abrin confers significantly higher levels of protection than treatment against ricin intoxication

(2015) Tamar Sabo et al.   TOXICOLOGY LETTERS

Safety and immunogenicity of ricin vaccine, RV Ec ™, in a Phase 1 clinical trial

(2015) Phillip R. Pittman et al.   VACCINE

Diverse Profiles of Ricin-Cell Interactions in the Lung Following Intranasal Exposure to Ricin

(2015) Anita Sapoznikov et al.   Toxins

Clinical and Pathological Findings Associated with Aerosol Exposure of Macaques to Ricin Toxin

(2015) Seth Pincus et al.   Toxins

Chimeric Plantibody Passively Protects Mice against Aerosolized Ricin Challenge

(2014) Erin K. Sully et al.   Clinical and Vaccine Immunology

Antibody-Mediated Inhibition of Ricin Toxin Retrograde Transport

(2014) A. Yermakova et al.   mBio

Combinations of Monoclonal Antibodies to Anthrax Toxin Manifest New Properties in Neutralization Assays

(2013) Mary Ann Pohl et al.   INFECTION AND IMMUNITY

Pathology of Lethal and Sublethal Doses of Aerosolized Ricin in Rhesus Macaques

(2013) Manoj Bhaskaran et al.   TOXICOLOGIC PATHOLOGY

Neutralizing activity and protective immunity to ricin toxin conferred by B subunit (RTB)-specific Fab fragments

(2013) Anastasiya Yermakova et al.   TOXICON

Current biodefense vaccine programs and challenges

(2013) Daniel N. Wolfe et al.   Human Vaccines & Immunotherapeutics

Role of Chemokines in the Pathogenesis of Acute Lung Injury

(2012) Madhav Bhatia et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pilot Phase IB Clinical Trial of an Alhydrogel-Adsorbed Recombinant Ricin Vaccine

(2012) Ellen S. Vitetta et al.   Clinical and Vaccine Immunology

Antibodies for biodefense

(2012) Jeffrey W. Froude et al.   mAbs

Sub-Domains of Ricin’s B Subunit as Targets of Toxin Neutralizing and Non-Neutralizing Monoclonal Antibodies

(2012) Anastasiya Yermakova et al.   PLoS One

Monoclonal Antibodies and Toxins—A Perspective on Function and Isotype

(2012) Siu-Kei Chow et al.   Toxins

Neutralising Antibodies against Ricin Toxin

(2011) Julie Prigent et al.   PLoS One

Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB)

(2011) Anastasiya Yermakova et al.   VACCINE

Role of the Mannose Receptor (CD206) in Innate Immunity to Ricin Toxin

(2011) Emily Gage et al.   Toxins

A requirement for FcγR in antibody-mediated bacterial toxin neutralization

(2010) Nareen Abboud et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Monoclonal Immunoglobulin G Antibody Directed against an Immunodominant Linear Epitope on the Ricin A Chain Confers Systemic and Mucosal Immunity to Ricin

(2009) L. M. Neal et al.   INFECTION AND IMMUNITY

Pulmonary Inflammation Triggered by Ricin Toxin Requires Macrophages and IL-1 Signaling

(2009) M. L. Lindauer et al.   JOURNAL OF IMMUNOLOGY