Intestinal restriction of Salmonella Typhimurium requires caspase-1 and caspase-11 epithelial intrinsic inflammasomes

Controlling Epithelial Polarity: A Human Enteroid Model for Host-Pathogen Interactions

(2019) Julia Y. Co et al.   Cell Reports

LPS targets host guanylate‐binding proteins to the bacterial outer membrane for non‐canonical inflammasome activation

(2018) José Carlos Santos et al.   EMBO JOURNAL

A Nonpyroptotic IFN-γ–Triggered Cell Death Mechanism in Nonphagocytic Cells PromotesSalmonellaClearance In Vivo

(2018) Justin P. Ingram et al.   JOURNAL OF IMMUNOLOGY

The Intestinal Epithelium: Central Coordinator of Mucosal Immunity

(2018) Joannie M. Allaire et al.   TRENDS IN IMMUNOLOGY

NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8

(2017) Isabella Rauch et al.   IMMUNITY

The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity

(2017) Katharina S. Schneider et al.   Cell Reports

IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection

(2017) Pierre Wallet et al.   PLoS Pathogens

Differential roles of caspase-1 and caspase-11 in infection and inflammation

(2017) Si Ming Man et al.   Scientific Reports

IFN-γ Hinders Recovery from Mucosal Inflammation during Antibiotic Therapy for Salmonella Gut Infection

(2016) Tamas Dolowschiak et al.   Cell Host & Microbe

Complement pathway amplifies caspase-11–dependent cell death and endotoxin-induced sepsis severity

(2016) Brooke A. Napier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death

(2016) Teresa L. M. Thurston et al.   Nature Communications

Epithelium-Intrinsic NAIP/NLRC4 Inflammasome Drives Infected Enterocyte Expulsion to Restrict Salmonella Replication in the Intestinal Mucosa

(2014) Mikael E. Sellin et al.   Cell Host & Microbe

Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens

(2014) Leigh A. Knodler et al.   Cell Host & Microbe

Intestinal Epithelium-Specific MyD88 Signaling Impacts Host Susceptibility to Infectious Colitis by Promoting Protective Goblet Cell and Antimicrobial Responses

(2014) Ganive Bhinder et al.   INFECTION AND IMMUNITY

Neutrophils Are a Source of Gamma Interferon during Acute Salmonella enterica Serovar Typhimurium Colitis

(2014) Alanna M. Spees et al.   INFECTION AND IMMUNITY

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

(2014) Etienne Meunier et al.   NATURE

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS

(2014) D. M. Pilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial Segregation of Virulence Gene Expression during Acute Enteric Infection with Salmonella enterica serovar Typhimurium

(2014) R. C. Laughlin et al.   mBio

Altered IFN- -Mediated Immunity and Transcriptional Expression Patterns in N-Ethyl-N-Nitrosourea-Induced STAT4 Mutants Confer Susceptibility to Acute Typhoid-like Disease

(2013) M. M. Eva et al.   JOURNAL OF IMMUNOLOGY

Salmonella Infection Induces Recruitment of Caspase-8 to the Inflammasome To Modulate IL-1  Production

(2013) S. M. Man et al.   JOURNAL OF IMMUNOLOGY

Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis

(2013) C Moon et al.   Mucosal Immunology

A T-bet gradient controls the fate and function of CCR6−RORγt+ innate lymphoid cells

(2013) Christoph S. N. Klose et al.   NATURE

In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture

(2013) Hiroyuki Miyoshi et al.   Nature Protocols

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

(2012) Vijay A.K. Rathinam et al.   CELL

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Stromal IFN-γR-Signaling Modulates Goblet Cell Function During Salmonella Typhimurium Infection

(2011) Pascal Songhet et al.   PLoS One

Dissemination of invasiveSalmonellavia bacterial-induced extrusion of mucosal epithelia

(2010) Leigh A. Knodler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contribution of Flagellin Pattern Recognition to Intestinal Inflammation during Salmonella enterica Serotype Typhimurium Infection

(2009) S. E. Winter et al.   INFECTION AND IMMUNITY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

T Cells Help To Amplify Inflammatory Responses Induced by Salmonella enterica Serotype Typhimurium in the Intestinal Mucosa

(2008) I. Godinez et al.   INFECTION AND IMMUNITY