C19orf66 interrupts Zika virus replication by inducing lysosomal degradation of viral NS3

NLRP3 Inflammasome Activation Mediates Zika Virus–Associated Inflammation

(2018) Zhenjian He et al.   JOURNAL OF INFECTIOUS DISEASES

Viperin Restricts Zika Virus and Tick-Borne Encephalitis Virus Replication by Targeting NS3 for Proteasomal Degradation

(2018) Christakis Panayiotou et al.   JOURNAL OF VIROLOGY

Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease

(2018) Qiang Ding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

(2018) Hongjie Xia et al.   Nature Communications

The emergence of Zika virus and its new clinical syndromes

(2018) Theodore C. Pierson et al.   NATURE

HIP1R targets PD-L1 to lysosomal degradation to alter T cell–mediated cytotoxicity

(2018) Huanbin Wang et al.   Nature Chemical Biology

Pseudorabies Virus dUTPase UL50 Induces Lysosomal Degradation of Type I Interferon Receptor 1 and Antagonizes the Alpha Interferon Response

(2017) Rui Zhang et al.   JOURNAL OF VIROLOGY

A single mutation in the prM protein of Zika virus contributes to fetal microcephaly

(2017) Ling Yuan et al.   SCIENCE

Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection

(2017) Sebastian Aguirre et al.   Nature Microbiology

Restriction of Zika Virus by Host Innate Immunity

(2016) Xuping Xie et al.   Cell Host & Microbe

IRAV ( FLJ11286 ), an Interferon-Stimulated Gene with Antiviral Activity against Dengue Virus, Interacts with MOV10

(2016) Corey A. Balinsky et al.   JOURNAL OF VIROLOGY

The Neurobiology of Zika Virus

(2016) Hongda Li et al.   NEURON

The IFITMs Inhibit Zika Virus Replication

(2016) George Savidis et al.   Cell Reports

Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication

(2016) Youichi Suzuki et al.   PLoS Pathogens

Lysosomes serve as a platform for hepatitis A virus particle maturation and nonlytic release

(2015) Nicole Seggewiß et al.   ARCHIVES OF VIROLOGY

PKA-dependent dynein switching from lysosomes to adenovirus: A novel form of host–virus competition

(2014) Julian Scherer et al.   JOURNAL OF CELL BIOLOGY

Rapid and reversible knockdown of endogenous proteins by peptide-directed lysosomal degradation

(2014) Xuelai Fan et al.   NATURE NEUROSCIENCE

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Phosphatidylinositol 3-Kinase-, Actin-, and Microtubule-Dependent Transport of Semliki Forest Virus Replication Complexes from the Plasma Membrane to Modified Lysosomes

(2010) P. Spuul et al.   JOURNAL OF VIROLOGY

Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein

(2010) Peter O Bauer et al.   NATURE BIOTECHNOLOGY

Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes

(2009) Monique Gannagé et al.   Cell Host & Microbe

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

(2009) Paul Saftig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY