Induction of HIF-1α by HIV-1 Infection in CD4+ T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation

Association of immune-activation and senescence markers with non-AIDS-defining comorbidities in HIV-suppressed patients

(2015) Pierre Duffau et al.   AIDS

Transcription regulates HIF-1α expression in CD4+ T cells

(2015) Thomas Bollinger et al.   IMMUNOLOGY AND CELL BIOLOGY

Exosomes from HIV-1-infected Cells Stimulate Production of Pro-inflammatory Cytokines through Trans-activating Response (TAR) RNA

(2015) Gavin C. Sampey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

(2015) Anna-Maria Herzner et al.   NATURE IMMUNOLOGY

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1

(2014) T. Umezu et al.   BLOOD

HIF Transcription Factors, Inflammation, and Immunity

(2014) Asis Palazon et al.   IMMUNITY

HIF-1 Alpha and Placental Growth Factor in Pregnancies Complicated With Preeclampsia: A Qualitative and Quantitative Analysis

(2014) Gayatri Rath et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis

(2014) T. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cells

(2014) Andrea Hegedus et al.   Retrovirology

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection

(2013) Clovis S. Palmer et al.   AIDS

Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

(2013) Laura A. Sena et al.   IMMUNITY

Exosomes Derived from HIV-1-infected Cells Contain Trans-activation Response Element RNA

(2013) Aarthi Narayanan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Vpr Modulates Macrophage Metabolic Pathways: A SILAC-Based Quantitative Analysis

(2013) Carlos A. Barrero et al.   PLoS One

MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling

(2013) J. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV

(2013) K. M. Monroe et al.   SCIENCE

Extracellular vesicle-mediated transfer of donor genomic DNA to recipient cells is a novel mechanism for genetic influence between cells

(2013) Jin Cai et al.   Journal of Molecular Cell Biology

Hypoxic enhancement of exosome release by breast cancer cells

(2012) Hamish W King et al.   BMC CANCER

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

(2011) Eric V. Dang et al.   CELL

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells

(2011) Lewis Z. Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue

(2010) Gilad Doitsh et al.   CELL

Trends in Multidrug Treatment Failure and Subsequent Mortality among Antiretroviral Therapy–Experienced Patients with HIV Infection in North America

(2009) Steven G. Deeks et al.   CLINICAL INFECTIOUS DISEASES

Activation of the Oxidative Stress Pathway by HIV-1 Vpr Leads to Induction of Hypoxia-inducible Factor 1α Expression

(2009) Satish L. Deshmane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection

(2008) Lewis H Kuller et al.   PLOS MEDICINE