Synthesis and Biological Evaluation of New (−)-Englerin Analogues

(−)-Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels

(2015) Yasemin Akbulut et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Total Synthesis of (−)-Englerin A through Catalytic Diastereo- and Enantioselective Carbonyl Ylide Cycloaddition

(2015) Taiki Hanari et al.   CHEMISTRY-A EUROPEAN JOURNAL

Total Synthesis of (±)-Englerin A Using An Intermolecular [3+2] Cycloaddition Reaction of Platinum-Containing Carbonyl Ylide

(2015) Hiroyuki Kusama et al.   Chemistry-An Asian Journal

Design and synthesis of terpene based englerin A mimics using chromium oxide mediated remote CH 2 oxidation

(2015) Mark J. Acerson et al.   TETRAHEDRON LETTERS

Total synthesis of (+/ − )-4-demethylenglerin A

(2014) Liang Dong et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Total synthesis of (−)-Englerin A

(2014) Jinghua Zhang et al.   TETRAHEDRON LETTERS

A Short Enantioselective Total Synthesis of (−)-Englerin A

(2013) Martin Zahel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Englerin A Stimulates PKCθ to Inhibit Insulin Signaling and to Simultaneously Activate HSF1: Pharmacologically Induced Synthetic Lethality

(2013) Carole Sourbier et al.   CANCER CELL

Collective Total Synthesis of Englerin A and B, Orientalol E and F, and Oxyphyllol: Application of the Organocatalytic [4+3] Cycloaddition Reaction

(2013) Jie Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Regioselectivity of the Intramolecular Biaryl Coupling Reaction of 3-Substituted Phenyl 2-Iodobenzoate using a Palladium Reagent

(2013) Hitoshi Abe et al.   HETEROCYCLES

Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy

(2013) Richard T Williams et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Progresses in Total Synthesis of Englerin A and Biological Evaluations of Its Analogues

(2012) Yunyu Lu et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Chlorinated Englerins with Selective Inhibition of Renal Cancer Cell Growth

(2012) Rhone K. Akee et al.   JOURNAL OF NATURAL PRODUCTS

Stereocontrolled Total Synthesis of (−)-Englerin A

(2012) Keisuke Takahashi et al.   JOURNAL OF ORGANIC CHEMISTRY

A Formal Synthesis of (−)-Englerin A by Relay Ring Closing Metathesis and Transannular Etherification

(2012) Jungyong Lee et al.   ORGANIC LETTERS

A Reductive-Heck Approach to the Hydroazulene Ring System: A Formal Synthesis of the Englerins

(2012) Peng Gao et al.   ORGANIC LETTERS

Englerin A Selectively Induces Necrosis in Human Renal Cancer Cells

(2012) Florian J. Sulzmaier et al.   PLoS One

Total Synthesis and Biological Evaluation of (−)-Englerin A and B: Synthesis of Analogues with Improved Activity Profile

(2011) Lea Radtke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Synthesis of the Englerins

(2011) Rebecca H. Pouwer et al.   Chemistry-An Asian Journal

Chemical Synthesis and Biological Evaluation of the Englerin Analogues

(2011) Kok Ping Chan et al.   ChemMedChem

A Brief Synthesis of (−)-Englerin A

(2011) Zhenwu Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis and Biological Evaluation of (−)-9-Deoxy-englerin A

(2011) Dmitry B. Ushakov et al.   ORGANIC LETTERS

Synthetic Strategies toward the Guaiane Sesquiterpene Englerin A

(2011) William Chain   SYNLETT

Enantioselective Synthesis of (−)-Englerins A and B

(2010) Kian Molawi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric, Protecting-Group-Free Total Synthesis of (−)-Englerin A

(2010) Qianghui Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Englerin A

(2010) K. C. Nicolaou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Towards artificial terpene cyclases

(2010) Matthieu Willot et al.   Nature Chemistry

Enantioselective Formal Synthesis of (−)-Englerin A via a Rh-Catalyzed [4 + 3] Cycloaddition Reaction

(2010) Jing Xu et al.   ORGANIC LETTERS

Synthesis of the Guaianolide Ring System via Cycloaddition of a Bicyclic Carbonyl Ylide with Allyl Propiolate

(2010) Vaidotas Navickas et al.   ORGANIC LETTERS

Concise approach to the core of englerin A via an organocatalytic [4+3] cycloaddition reaction

(2010) Bing-Feng Sun et al.   TETRAHEDRON LETTERS

Total Synthesis and Absolute Configuration of the Guaiane Sesquiterpene Englerin A

(2009) Matthieu Willot et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective gold-catalyzed cycloaddition of functionalized ketoenynes: synthesis of (+)-orientalol F

(2009) Eloísa Jiménez-Núñez et al.   CHEMICAL COMMUNICATIONS

Englerin A, a Selective Inhibitor of Renal Cancer Cell Growth, fromPhyllanthus engleri

(2008) Ranjala Ratnayake et al.   ORGANIC LETTERS

Homogeneous Hydrogenation of Tri- and Tetrasubstituted Olefins: Comparison of Iridium-Phospinooxazoline [Ir-PHOX] Complexes and Crabtree Catalysts with Hexafluorophosphate (PF6) and Tetrakis[3,5-bis(trifluoromethyl)phenyl]borate (BArF) as Counterions

(2007) Bettina Wüstenberg et al.   ADVANCED SYNTHESIS & CATALYSIS