A Novel Way To Radiolabel Human Butyrylcholinesterase for Positron Emission Tomography through Irreversible Transfer of the Radiolabeled Moiety

A Novel Radiotracer for Imaging Monoacylglycerol Lipase in the Brain Using Positron Emission Tomography

(2016) Changning Wang et al.   ACS Chemical Neuroscience

Learning performances and vulnerability to amyloid toxicity in the butyrylcholinesterase knockout mouse

(2016) Tangui Maurice et al.   BEHAVIOURAL BRAIN RESEARCH

Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode

(2016) Edgar Sawatzky et al.   JOURNAL OF MEDICINAL CHEMISTRY

Effects of Rivastigmine and Donepezil on Brain Acetylcholine Levels in Acetylcholinesterase-Deficient Mice

(2016) Runa S. Naik et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Organic Carbamates in Drug Design and Medicinal Chemistry

(2015) Arun K. Ghosh et al.   JOURNAL OF MEDICINAL CHEMISTRY

In Vivo and In Vitro Characterization of a Novel MAO-B Inhibitor Radioligand, 18F-Labeled Deuterated Fluorodeprenyl

(2015) S. Nag et al.   JOURNAL OF NUCLEAR MEDICINE

Immunohistochemical analysis of hippocampal butyrylcholinesterase: Implications for regional vulnerability in Alzheimer's disease

(2015) Katsuyoshi Mizukami et al.   NEUROPATHOLOGY

Butyrylcholinesterase-knockout reduces brain deposition of fibrillar β-amyloid in an Alzheimer mouse model

(2015) G. Andrew Reid et al.   NEUROSCIENCE

Review of human butyrylcholinesterase structure, function, genetic variants, history of use in the clinic, and potential therapeutic uses

(2015) Oksana Lockridge   PHARMACOLOGY & THERAPEUTICS

A Novel Fluorine-18 β-Fluoroethoxy Organophosphate Positron Emission Tomography Imaging Tracer Targeted to Central Nervous System Acetylcholinesterase

(2014) Shelly L. James et al.   ACS Chemical Neuroscience

Identification of a neuroprotective and selective butyrylcholinesterase inhibitor derived from the natural alkaloid evodiamine

(2014) Guozheng Huang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

PET Imaging of Fatty Acid Amide Hydrolase with [18F]DOPP in Nonhuman Primates

(2014) Benjamin H. Rotstein et al.   MOLECULAR PHARMACEUTICS

Radiosynthesis and ex vivo evaluation of [11C-carbonyl]carbamate- and urea-based monoacylglycerol lipase inhibitors

(2014) Justin W. Hicks et al.   NUCLEAR MEDICINE AND BIOLOGY

Investigation into selective debenzylation and ring cleavage of quinazoline based heterocycles

(2014) Edgar Sawatzky et al.   TETRAHEDRON LETTERS

Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase

(2013) Oleg Sadovski et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Development of a novel fluorine-18 labeled deuterated fluororasagiline ([18F]fluororasagiline-D2) radioligand for PET studies of monoamino oxidase B (MAO-B)

(2013) S. Nag et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and evaluation of (−)- and (+)-[11C]galanthamine as PET tracers for cerebral acetylcholinesterase imaging

(2013) Hiroyuki Kimura et al.   BIOORGANIC & MEDICINAL CHEMISTRY

11CO2 fixation: a renaissance in PET radiochemistry

(2013) Benjamin H. Rotstein et al.   CHEMICAL COMMUNICATIONS

Serum butyrylcholinesterase and the risk of future type 2 diabetes: the Kansai Healthcare Study

(2013) Kyoko Kogawa Sato et al.   CLINICAL ENDOCRINOLOGY

PET probes for imaging brain acetylcholinesterase

(2013) Tatsuya Kikuchi et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Alternative approaches for PET radiotracer development in Alzheimer's disease: imaging beyond plaque

(2013) Jason P. Holland et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Synthesis and preclinical evaluation of [11C-carbonyl]PF-04457845 for neuroimaging of fatty acid amide hydrolase

(2013) Justin W. Hicks et al.   NUCLEAR MEDICINE AND BIOLOGY

Synthesis and evaluation of [18F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B)

(2012) S. Nag et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Butyrylcholinesterase radioligands to image Alzheimer’s disease brain

(2012) Sultan Darvesh   CHEMICO-BIOLOGICAL INTERACTIONS

Mapping Human Brain Fatty Acid Amide Hydrolase Activity with PET

(2012) Pablo M Rusjan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Radiosynthesis and Evaluation of [11C-Carbonyl]-Labeled Carbamates as Fatty Acid Amide Hydrolase Radiotracers for Positron Emission Tomography

(2012) Alan A. Wilson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Neuroprotective Tri- and Tetracyclic BChE Inhibitors Releasing Reversible Inhibitors upon Carbamate Transfer

(2012) Fouad H. Darras et al.   ACS Medicinal Chemistry Letters

Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-β peptide in mice

(2011) Yoko Furukawa-Hibi et al.   BEHAVIOURAL BRAIN RESEARCH

Butyrylcholinesterase activity in young men and women: Association with cardiovascular risk factors

(2011) Marina Stojanov et al.   CLINICAL BIOCHEMISTRY

Butyrylcholinesterase Is Associated With β-Amyloid Plaques in the Transgenic APPSWE/PSEN1dE9 Mouse Model of Alzheimer Disease

(2011) Sultan Darvesh et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Binding of 2-[18F]fluoro-CP-118,954 to mouse acetylcholinesterase: microPET and ex vivo Cerenkov luminescence imaging studies

(2011) Dong Hyun Kim et al.   NUCLEAR MEDICINE AND BIOLOGY

The cholinergic system and Parkinson disease

(2010) Nicolaas I. Bohnen et al.   BEHAVIOURAL BRAIN RESEARCH

The cholinergic system in aging and neuronal degeneration

(2010) Reinhard Schliebs et al.   BEHAVIOURAL BRAIN RESEARCH

Synthesis and Application of Isocyanates Radiolabeled with Carbon-11

(2010) Alan A. Wilson et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis and Preliminary Evaluation of Piperidinyl and Pyrrolidinyl Iodobenzoates as Imaging Agents for Butyrylcholinesterase

(2010) Ian R. Macdonald et al.   MOLECULAR IMAGING AND BIOLOGY

Cholinergic system function and cognition in mild cognitive impairment

(2010) Cathleen Haense et al.   NEUROBIOLOGY OF AGING

Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-l-deprenyl using whole hemisphere autoradiography

(2010) Balázs Gulyás et al.   NEUROCHEMISTRY INTERNATIONAL

[11C]CURB: Evaluation of a novel radiotracer for imaging fatty acid amide hydrolase by positron emission tomography

(2010) Alan A. Wilson et al.   NUCLEAR MEDICINE AND BIOLOGY

The butyrylcholinesterase knockout mouse is obese on a high-fat diet

(2008) Bin Li et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Acetylcholine esterase activity in mild cognitive impairment and Alzheimer’s disease

(2008) Karl Herholz   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications

(2008) Elliott J Mufson et al.   Expert Review of Neurotherapeutics

Isosorbide-2-carbamate Esters: Potent and Selective Butyrylcholinesterase Inhibitors

(2008) Ciaran G. Carolan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Carbamates with Differential Mechanism of Inhibition Toward Acetylcholinesterase and Butyrylcholinesterase

(2008) Sultan Darvesh et al.   JOURNAL OF MEDICINAL CHEMISTRY

1-11C-Methyl-4-Piperidinyl-N-Butyrate Radiation Dosimetry in Humans by Dynamic Organ-Specific Evaluation

(2008) J. R. Virta et al.   JOURNAL OF NUCLEAR MEDICINE