PET probes for imaging brain acetylcholinesterase

Thalamic cholinergic innervation is spared in Alzheimer disease compared to parkinsonian disorders

(2012) Vikas Kotagal et al.   NEUROSCIENCE LETTERS

Greater Responsiveness to Donepezil in Alzheimer Patients With Higher Levels of Acetylcholinesterase Based on Attention Task Scores and a Donepezil PET Study

(2011) Masashi Kasuya et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Radionuclide brain imaging correlates of cognitive impairment in Parkinson's disease (PD)

(2011) Flavio Nobili et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Cerebral acetylcholinesterase activity is not decreased in MS patients with cognitive impairment

(2011) Jere R Virta et al.   Multiple Sclerosis Journal

Effect of radiolabeled metabolite elimination from the brain on the accuracy of cerebral enzyme activity estimation using positron emission tomography with substrate tracers

(2011) Tomoyuki Ohya et al.   NEUROIMAGE

Cholinergic dysfunction after traumatic brain injury: Preliminary findings from a PET study

(2011) A. Ostberg et al.   NEUROLOGY

Binding of 2-[18F]fluoro-CP-118,954 to mouse acetylcholinesterase: microPET and ex vivo Cerenkov luminescence imaging studies

(2011) Dong Hyun Kim et al.   NUCLEAR MEDICINE AND BIOLOGY

Piperidine-4-methanthiol Ester Derivatives for a Selective Acetylcholinesterase Assay

(2010) Tatsuya Kikuchi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Use of a novel radiometric method to assess the inhibitory effect of donepezil on acetylcholinesterase activity in minimally diluted tissue samples

(2010) Tatsuya Kikuchi et al.   BRITISH JOURNAL OF PHARMACOLOGY

PET Imaging of MRP1 Function in the Living Brain: Method Development and Future Perspectives

(2010) T. Okamura et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Cerebral cortical and subcortical cholinergic deficits in parkinsonian syndromes

(2010) S. Gilman et al.   NEUROLOGY

In vivo detection of neuropathologic changes in presymptomatic MAPT mutation carriers: A PET and MRI study

(2010) Michie Miyoshi et al.   PARKINSONISM & RELATED DISORDERS

Reactivity of 6-Halopurine Analogs with Glutathione as a Radiotracer for Assessing Function of Multidrug Resistance-Associated Protein 1

(2009) Toshimitsu Okamura et al.   JOURNAL OF MEDICINAL CHEMISTRY

Quantitative analysis of donepezil binding to acetylcholinesterase using positron emission tomography and [5-11C-methoxy]donepezil

(2009) Kotaro Hiraoka et al.   NEUROIMAGE

Age-associated leukoaraiosis and cortical cholinergic deafferentation

(2009) N. I. Bohnen et al.   NEUROLOGY

Mapping of brain acetylcholinesterase alterations in Lewy body disease by PET

(2009) H. Shimada et al.   NEUROLOGY

History of falls in Parkinson disease is associated with reduced cholinergic activity

(2009) N. I. Bohnen et al.   NEUROLOGY

In vivo visualization of donepezil binding in the brain of patients with Alzheimer's disease

(2008) Nobuyuki Okamura et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Noninvasive and Quantitative Assessment of the Function of Multidrug Resistance-Associated Protein 1 in the Living Brain

(2008) Toshimitsu Okamura et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

PET study of brain acetylcholinesterase in cerebellar degenerative disorders

(2008) Shigeki Hirano et al.   MOVEMENT DISORDERS

Facile synthesis of new carbon-11 labeled conformationally restricted rivastigmine analogues as potential PET agents for imaging AChE and BChE enzymes

(2007) Min Wang et al.   APPLIED RADIATION AND ISOTOPES

PET imaging of the in vivo brain acetylcholinesterase activity and nicotine binding in galantamine-treated patients with AD

(2007) A. Kadir et al.   NEUROBIOLOGY OF AGING

Inhibition of acetylcholinesterase in CSF versus brain assessed by 11C-PMP PET in AD patients treated with galantamine

(2006) T. Darreh-Shori et al.   NEUROBIOLOGY OF AGING