Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2
Authors
Keywords
-
Journal
Scientific Reports
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-03-13
DOI
10.1038/s41598-020-61295-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Histone Deacetylase 11 Is a Fatty-Acid Deacylase
- (2018) Zsofia Kutil et al. ACS Chemical Biology
- Histone Deacetylase Inhibitors as a Novel Targeted Therapy Against Non-small Cell Lung Cancer: Where Are We Now and What Should We Expect?
- (2018) ANTICANCER RESEARCH
- Discovery of novel N -hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11
- (2018) Matthew W. Martin et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer
- (2018) Matthew D. Hellmann et al. CANCER CELL
- Targeting immune checkpoints in non small cell lung cancer
- (2018) Andrea Bianco et al. CURRENT OPINION IN PHARMACOLOGY
- Third generation EGFR TKIs: current data and future directions
- (2018) Chee-Seng Tan et al. Molecular Cancer
- Novel approaches against epidermal growth factor receptor tyrosine kinase inhibitor resistance
- (2018) Carina Heydt et al. Oncotarget
- Programming and Regulation of Metabolic Homeostasis by HDAC11
- (2018) Lei Sun et al. EBioMedicine
- Immunotherapy in Non-Small Cell Lung Cancer: Shifting Prognostic Paradigms
- (2018) Megan B. Barnet et al. Journal of Clinical Medicine
- HDAC6 differentially regulates autophagy in stem-like versus differentiated cancer cells
- (2018) Tanveer Sharif et al. Autophagy
- Histone Deacetylase Inhibitors as Anticancer Drugs
- (2017) Tomas Eckschlager et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Up-regulation of glycolysis promotes the stemness and EMT phenotypes in gemcitabine-resistant pancreatic cancer cells
- (2017) Hengqiang Zhao et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Subcellular localisation of the stem cell markers OCT4, SOX2, NANOG, KLF4 and c-MYC in cancer: a review
- (2017) Bede van Schaijik et al. JOURNAL OF CLINICAL PATHOLOGY
- Cancer stem cells revisited
- (2017) Eduard Batlle et al. NATURE MEDICINE
- Cancer stem cells: The root of tumor recurrence and metastases
- (2017) Claudia Peitzsch et al. SEMINARS IN CANCER BIOLOGY
- The challenge of targeting cancer stem cells to halt metastasis
- (2017) Alice Agliano et al. SEMINARS IN CANCER BIOLOGY
- Cisplatin-enriching cancer stem cells confer multidrug resistance in non-small cell lung cancer via enhancing TRIB1/HDAC activity
- (2017) Lihui Wang et al. Cell Death & Disease
- Cancer associated fibroblasts: An essential role in the tumor microenvironment
- (2017) Leilei Tao et al. Oncology Letters
- Acetylation and deacetylation in cancer stem-like cells
- (2017) Na Liu et al. Oncotarget
- SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin
- (2016) Giustina Ferone et al. CANCER CELL
- Platinum-based chemotherapy in advanced non-small-cell lung cancer: optimal number of treatment cycles
- (2016) Antonio Rossi et al. Expert Review of Anticancer Therapy
- Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog
- (2016) Hanna Tukachinsky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The tumor microenvironment promotes cancer progression and cell migration
- (2016) Viviana Salvatore et al. Oncotarget
- HDACs and HDAC Inhibitors in Cancer Development and Therapy
- (2016) Yixuan Li et al. Cold Spring Harbor Perspectives in Medicine
- -Arrestin-1 Mediates Nicotine-Induced Metastasis through E2F1 Target Genes That Modulate Epithelial-Mesenchymal Transition
- (2015) S. Pillai et al. CANCER RESEARCH
- YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate Self-Renewal and Vascular Mimicry of Stem-Like Cells
- (2015) Namrata Bora-Singhal et al. STEM CELLS
- Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non–Small Cell Lung Cancer
- (2015) Namrata Bora-Singhal et al. NEOPLASIA
- Sox2: Masterminding the Root of Cancer
- (2014) Wai Leong Tam et al. CANCER CELL
- Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis
- (2014) A. N. Lau et al. EMBO JOURNAL
- New and emerging HDAC inhibitors for cancer treatment
- (2014) Alison C. West et al. JOURNAL OF CLINICAL INVESTIGATION
- Basic Mechanisms of Therapeutic Resistance to Radiation and Chemotherapy in Lung Cancer
- (2013) Henning Willers et al. CANCER JOURNAL
- Lung cancer stem cells: Molecular features and therapeutic targets
- (2013) Sandeep Singh et al. MOLECULAR ASPECTS OF MEDICINE
- Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms
- (2013) J. Li et al. Molecular Systems Biology
- Metastasis Awakening: Targeting dormant cancer
- (2013) Julio A Aguirre-Ghiso et al. NATURE MEDICINE
- βArrestin-1 and Mcl-1 Modulate Self-Renewal Growth of Cancer Stem-Like Side-Population Cells in Non-Small Cell Lung Cancer
- (2013) Sandeep Singh et al. PLoS One
- Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer
- (2013) Balázs Győrffy et al. PLoS One
- Chemotherapy and Targeted Therapeutics as Maintenance of Response in Advanced Non-Small Cell Lung Cancer
- (2013) Melissa L. Johnson et al. SEMINARS IN ONCOLOGY
- A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review)
- (2013) YUN-LONG FAN et al. Oncology Letters
- Lung cancer stem cells: a biological and clinical perspective
- (2013) Ana Koren et al. CELLULAR ONCOLOGY
- Lung cancer stem cells: Progress and prospects
- (2012) Amber Lundin et al. CANCER LETTERS
- Phosphoproteomics Identifies Driver Tyrosine Kinases in Sarcoma Cell Lines and Tumors
- (2012) Y. Bai et al. CANCER RESEARCH
- Lung carcinogenesis by tobacco smoke
- (2012) Stephen S. Hecht INTERNATIONAL JOURNAL OF CANCER
- HDAC11 is a novel drug target in carcinomas
- (2012) Hedwig E. Deubzer et al. INTERNATIONAL JOURNAL OF CANCER
- Expression of Sox2 and Oct4 and Their Clinical Significance in Human Non-Small-Cell Lung Cancer
- (2012) Xinxin Li et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- EGFR–TKI resistant non-small cell lung cancer (NSCLC): New developments and implications for future treatment
- (2012) Wolfram Brugger et al. LUNG CANCER
- EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer
- (2012) Sandeep Singh et al. Molecular Cancer
- Cancer stem cells, tumor dormancy, and metastasis
- (2012) Purvi Patel et al. Frontiers in Endocrinology
- CD133+ Glioblastoma Stem-Like Cells Induce Vascular Mimicry in Vivo
- (2011) Ming-Tsang Chiao et al. CURRENT NEUROVASCULAR RESEARCH
- Directed cell invasion and migration during metastasis
- (2011) Jose Javier Bravo-Cordero et al. CURRENT OPINION IN CELL BIOLOGY
- Overcoming anoikis - pathways to anchorage-independent growth in cancer
- (2011) M. C. Guadamillas et al. JOURNAL OF CELL SCIENCE
- ARRB1-Mediated Regulation of E2F Target Genes in Nicotine-Induced Growth of Lung Tumors
- (2011) Piyali Dasgupta et al. JNCI-Journal of the National Cancer Institute
- SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity
- (2011) Munehide Nakatsugawa et al. LABORATORY INVESTIGATION
- Initial steps of metastasis: Cell invasion and endothelial transmigration
- (2011) Franziska van Zijl et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- HDAC1 regulates pluripotency and lineage specific transcriptional networks in embryonic and trophoblast stem cells
- (2011) Benjamin L. Kidder et al. NUCLEIC ACIDS RESEARCH
- Sox2 expression in breast tumours and activation in breast cancer stem cells
- (2011) O Leis et al. ONCOGENE
- A Small Molecule Disruptor of Rb/Raf-1 Interaction Inhibits Cell Proliferation, Angiogenesis, and Growth of Human Tumor Xenografts in Nude Mice
- (2008) R. Kinkade et al. CANCER RESEARCH
- Mst2 and Lats Kinases Regulate Apoptotic Function of Yes Kinase-associated Protein (YAP)
- (2008) Tsutomu Oka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance
- (2008) Alejandro Villagra et al. NATURE IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started