Slco2a1 deficiency exacerbates experimental colitis via inflammasome activation in macrophages: a possible mechanism of chronic enteropathy associated with SLCO2A1 gene

Measurement of prostaglandin metabolites is useful in diagnosis of small bowel ulcerations

(2019) Yuichi Matsuno et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Prostaglandin transporter OATP2A1/SLCO2A1is essential for body temperature regulation during fever

(2018) Yoshinobu Nakamura et al.   JOURNAL OF NEUROSCIENCE

Prostaglandin-cytokine crosstalk in chronic inflammation

(2018) Chengcan Yao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Intestinal Inflammation and Dysregulated Immunity in Patients With Inherited Caspase-8 Deficiency

(2018) Anna S. Lehle et al.   GASTROENTEROLOGY

The Induction of Pro–IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E2Production

(2017) Zbigniew Zasłona et al.   JOURNAL OF IMMUNOLOGY

A novel role for OATP2A1/SLCO2A1 in a murine model of colon cancer

(2017) Takeo Nakanishi et al.   Scientific Reports

Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation

(2016) Michael J. Primiano et al.   JOURNAL OF IMMUNOLOGY

Role of Inflammasomes in Intestinal Inflammation and Crohnʼs Disease

(2015) Anthony Opipari et al.   INFLAMMATORY BOWEL DISEASES

Mechanisms of NLRP3 inflammasome activation and its role in NSAID-induced enteropathy

(2015) A Higashimori et al.   Mucosal Immunology

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

Prostaglandin Transporter (PGT/SLCO2A1) Protects the Lung from Bleomycin-Induced Fibrosis

(2015) Takeo Nakanishi et al.   PLoS One

Multiple drug resistance-associated protein 4 (MRP4), prostaglandin transporter (PGT), and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) as determinants of PGE2 levels in cancer

(2015) Tyler J. Kochel et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

(2015) Y. Zhang et al.   SCIENCE

Three cheers for the goblet cell: maintaining homeostasis in mucosal epithelia

(2015) Heather A. McCauley et al.   TRENDS IN MOLECULAR MEDICINE

A Hereditary Enteropathy Caused by Mutations in the SLCO2A1 Gene, Encoding a Prostaglandin Transporter

(2015) Junji Umeno et al.   PLoS Genetics

Paneth Cells: Maestros of the Small Intestinal Crypts

(2013) Hans C. Clevers et al.   Annual Review of Physiology

Protective and Aggravating Effects of Nlrp3 Inflammasome Activation in IBD Models: Influence of Genetic and Environmental Factors

(2012) Christian Bauer et al.   DIGESTIVE DISEASES

Cox-2 deletion in myeloid and endothelial cells, but not in epithelial cells, exacerbates murine colitis.

(2010) T.-o. Ishikawa et al.   CARCINOGENESIS

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

(2010) C. Bauer et al.   GUT

Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohnʼs disease

(2010) S. C. Ng et al.   INFLAMMATORY BOWEL DISEASES

Present status and strategy of NSAIDs-induced small bowel injury

(2009) Kazuhide Higuchi et al.   JOURNAL OF GASTROENTEROLOGY

Early molecular and functional changes in colonic epithelium that precede increased gut permeability during colitis development in mdr1a(−/−) mice

(2008) Andrew Collett et al.   INFLAMMATORY BOWEL DISEASES