The Protective Effects of Acer okamotoanum and Isoquercitrin on Obesity and Amyloidosis in a Mouse Model

Liver Dysfunction as a Novel Player in Alzheimer’s Progression: Looking Outside the Brain

(2019) Lisbell D. Estrada et al.   Frontiers in Aging Neuroscience

Non-Alcoholic Fatty Liver Disease, and the Underlying Altered Fatty Acid Metabolism, Reveals Brain Hypoperfusion and Contributes to the Cognitive Decline in APP/PS1 Mice

(2019) Anthony Pinçon et al.   Metabolites

Effects of thymol on amyloid-β-induced impairments in hippocampal synaptic plasticity in rats fed a high-fat diet

(2018) Masoumeh Asadbegi et al.   BRAIN RESEARCH BULLETIN

Virgin coconut oil (VCO) by normalizing NLRP3 inflammasome showed potential neuroprotective effects in Amyloid-β induced toxicity and high-fat diet fed rat

(2018) Fatemeh Mirzaei et al.   FOOD AND CHEMICAL TOXICOLOGY

Acer okamotoanum protects SH-SY5Y neuronal cells against hydrogen peroxide-induced oxidative stress

(2018) Ji Hyun Kim et al.   FOOD SCIENCE AND BIOTECHNOLOGY

Determination of flavonoids in Acer okamotoanum and their aldose reductase inhibitory activities

(2018) Jaemin Lee et al.   Horticulture Environment and Biotechnology

Raspberry ketone preserved cholinergic activity and antioxidant defense in obesity induced Alzheimer disease in rats

(2018) Hoda E. Mohamed et al.   BIOMEDICINE & PHARMACOTHERAPY

Isoquercetin Improves Hepatic Lipid Accumulation by Activating AMPK Pathway and Suppressing TGF-β Signaling on an HFD-Induced Nonalcoholic Fatty Liver Disease Rat Model

(2018) Guohong Qin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

γ-Aminobutyric Acid Attenuates High-Fat Diet-Induced Cerebral Oxidative Impairment via Enhanced Synthesis of Hippocampal Sulfatides

(2018) Xu Si et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Alpha-Linolenic Acid from Perilla frutescens var. japonica Oil Protects Aβ-Induced Cognitive Impairment through Regulation of APP Processing and Aβ Degradation

(2017) Ah Young Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Complexity and Selectivity of γ-Secretase Cleavage on Multiple Substrates: Consequences in Alzheimer’s Disease and Cancer

(2017) Alessandro Medoro et al.   JOURNAL OF ALZHEIMERS DISEASE

Xuefu Zhuyu decoction ameliorates obesity, hepatic steatosis, neuroinflammation, amyloid deposition and cognition impairment in metabolically stressed APPswe/PS1dE9 mice

(2017) Chih-Wen Yeh et al.   JOURNAL OF ETHNOPHARMACOLOGY

Investigation of thymol effect on learning and memory impairment induced by intrahippocampal injection of amyloid beta peptide in high fat diet- fed rats

(2017) Masoumeh Asadbegi et al.   METABOLIC BRAIN DISEASE

Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse model of Alzheimer's disease

(2017) Jennifer M. Walker et al.   NEUROBIOLOGY OF DISEASE

The effects of paternal high-fat diet exposure on offspring metabolism with epigenetic changes in the mouse adiponectin and leptin gene promoters

(2016) Hisashi Masuyama et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Assessment of neuroinflammation in a mouse model of obesity and β-amyloidosis using PET

(2016) Anna M. Barron et al.   Journal of Neuroinflammation

Non-alcoholic fatty liver disease induces signs of Alzheimer’s disease (AD) in wild-type mice and accelerates pathological signs of AD in an AD model

(2016) Do-Geun Kim et al.   Journal of Neuroinflammation

Using Multicountry Ecological and Observational Studies to Determine Dietary Risk Factors for Alzheimer's Disease

(2016) William B. Grant   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Relationship Between Obesity, Alzheimer’s Disease, and Parkinson’s Disease: an Astrocentric View

(2016) Cynthia Alexandra Martin-Jiménez et al.   MOLECULAR NEUROBIOLOGY

High fat diet exacerbates Alzheimer’s disease-related pathology in APPswe/PS1 mice

(2016) Peter Thériault et al.   Oncotarget

Therapies for Prevention and Treatment of Alzheimer’s Disease

(2016) J. Mendiola-Precoma et al.   Biomed Research International

High‐Fat‐Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer's Disease, Independently of Metabolic Disorders

(2016) Bowen Lin et al.   Journal of the American Heart Association

Acer okamotoanum improves cognition and memory function in Aβ25–35-induced Alzheimer’s mice model

(2016) Soo Yeon Choi et al.   Applied Biological Chemistry

Insulin Resistance as Common Molecular Denominator Linking Obesity to Alzheimer’s Disease

(2015) Domenico Nuzzo et al.   Current Alzheimer Research

Examining the relationship between obesity and cognitive function: A systematic literature review

(2015) Christina Prickett et al.   Obesity Research & Clinical Practice

Obesity and Hepatic Steatosis Are Associated with Elevated Serum Amyloid Beta in Metabolically Stressed APPswe/PS1dE9 Mice

(2015) Feng-Shiun Shie et al.   PLoS One

Isoquercitrin activates the AMP–activated protein kinase (AMPK) signal pathway in rat H4IIE cells

(2014) Jingxin Zhou et al.   BMC Complementary and Alternative Medicine

Targeting the β secretase BACE1 for Alzheimer's disease therapy

(2014) Riqiang Yan et al.   LANCET NEUROLOGY

High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology

(2014) Elysse M. Knight et al.   NEUROBIOLOGY OF AGING

A brief overview of amyloids and Alzheimer's disease

(2014) Sian-Yang Ow et al.   PROTEIN SCIENCE

Obesity in Aging Exacerbates Blood-Brain Barrier Disruption, Neuroinflammation, and Oxidative Stress in the Mouse Hippocampus: Effects on Expression of Genes Involved in Beta-Amyloid Generation and Alzheimer's Disease

(2013) Z. Tucsek et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Health benefits of conjugated linoleic acid (CLA)

(2013) Kazunori Koba et al.   Obesity Research & Clinical Practice

Continuation of Exercise Is Necessary to Inhibit High Fat Diet-Induced β-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic Mice

(2013) Masato Maesako et al.   PLoS One

Effects of Acer okamotoanum sap on the function of polymorphonuclear neutrophilic leukocytes in vitro and in vivo

(2012) BEUM-SOO AN et al.   Molecular Medicine Reports

Global obesity: trends, risk factors and policy implications

(2012) Vasanti S. Malik et al.   Nature Reviews Endocrinology

The sap of Acer okamotoanum decreases serum alcohol levels after acute ethanol ingestion in rats

(2011) Eui-Bae Jeung   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Gami-Chunghyuldan ameliorates memory impairment and neurodegeneration induced by intrahippocampal Aβ1–42 oligomer injection

(2011) Jin Gyu Choi et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Persicaria hydropiper(L.) Spach and its Flavonoid Components, Isoquercitrin and Isorhamnetin, Activate the Wnt/β-catenin Pathway and Inhibit Adipocyte Differentiation of 3T3-L1 Cells

(2011) Soung-Hoon Lee et al.   PHYTOTHERAPY RESEARCH