Obesity in Aging Exacerbates Blood-Brain Barrier Disruption, Neuroinflammation, and Oxidative Stress in the Mouse Hippocampus: Effects on Expression of Genes Involved in Beta-Amyloid Generation and Alzheimer's Disease
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Obesity in Aging Exacerbates Blood-Brain Barrier Disruption, Neuroinflammation, and Oxidative Stress in the Mouse Hippocampus: Effects on Expression of Genes Involved in Beta-Amyloid Generation and Alzheimer's Disease
Authors
Keywords
-
Journal
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
Volume 69, Issue 10, Pages 1212-1226
Publisher
Oxford University Press (OUP)
Online
2013-11-23
DOI
10.1093/gerona/glt177
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Immunoglobulin G Fc receptor deficiency prevents Alzheimer-like pathology and cognitive impairment in mice
- (2012) P. Fernandez-Vizarra et al. BRAIN
- Treatment with the cytochrome P450 ω-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats
- (2012) Peter Toth et al. BRITISH JOURNAL OF PHARMACOLOGY
- Resveratrol Attenuates Obesity-Associated Peripheral and Central Inflammation and Improves Memory Deficit in Mice Fed a High-Fat Diet
- (2012) B. T. Jeon et al. DIABETES
- Detrimental Effects of Diet-Induced Obesity on Pathology Are Independent of Insulin Resistance in Transgenic Mice
- (2012) A. Leboucher et al. DIABETES
- High-fat-diet exposure induces IgG accumulation in hypothalamic microglia
- (2012) C.-X. Yi et al. Disease Models & Mechanisms
- Exercise Is More Effective than Diet Control in Preventing High Fat Diet-induced β-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic Mice
- (2012) Masato Maesako et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit
- (2012) Jérôme Badaut et al. Journal of Neuroinflammation
- Associations Between Arterial Elasticity and Markers of Inflammation in Healthy Older Women
- (2012) G. Fisher et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Long-term Assessment of Inflammation and Healthy Aging in Late Life: The Cardiovascular Health Study All Stars
- (2012) Nancy S. Jenny et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Total and Abdominal Adiposity Are Associated With Inflammation in Older Adults Using a Factor Analysis Approach
- (2012) Tina E. Brinkley et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Testing the Oxidative Stress Hypothesis of Aging in Primate Fibroblasts: Is There a Correlation Between Species Longevity and Cellular ROS Production?
- (2012) A. Csiszar et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Aging-Induced Dysregulation of Dicer1-Dependent MicroRNA Expression Impairs Angiogenic Capacity of Rat Cerebromicrovascular Endothelial Cells
- (2012) Z. Ungvari et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Circulating Factors Induced by Caloric Restriction in the Nonhuman Primate Macaca Mulatta Activate Angiogenic Processes in Endothelial Cells
- (2012) A. Csiszar et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Aging Exacerbates Obesity-Induced Oxidative Stress and Inflammation in Perivascular Adipose Tissue in Mice: A Paracrine Mechanism Contributing to Vascular Redox Dysregulation and Inflammation
- (2012) L. C. Bailey-Downs et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Disruption of Nrf2 Signaling Impairs Angiogenic Capacity of Endothelial Cells: Implications for Microvascular Aging
- (2012) M. N. Valcarcel-Ares et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Age-Associated Proinflammatory Secretory Phenotype in Vascular Smooth Muscle Cells From the Non-human Primate Macaca mulatta: Reversal by Resveratrol Treatment
- (2012) A. Csiszar et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Microglial Activation in Neuroinflammation: Implications for the Etiology of Neurodegeneration
- (2012) Yoko S. Kaneko et al. Neurodegenerative Diseases
- Chronic peripheral hyperinsulinemia has no substantial influence on tau phosphorylation in vivo
- (2012) Katrin Becker et al. NEUROSCIENCE LETTERS
- Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation
- (2012) Dimitrios Davalos et al. Nature Communications
- The association between systemic inflammation and cognitive performance in the elderly: the Sydney Memory and Ageing Study
- (2011) Julian N. Trollor et al. AGE
- Vascular Changes in Rat Hippocampus following a High Saturated Fat and Cholesterol Diet
- (2011) Linnea R Freeman et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
- (2011) Berislav V. Zlokovic NATURE REVIEWS NEUROSCIENCE
- Environmental enrichment ameliorated high-fat diet-induced Aβ deposition and memory deficit in APP transgenic mice
- (2011) Masato Maesako et al. NEUROBIOLOGY OF AGING
- Adiponectin-Deficiency Exaggerates Sepsis-Induced Microvascular Dysfunction in the Mouse Brain
- (2011) Vidula Vachharajani et al. Obesity
- Vascular Contributions to Cognitive Impairment and Dementia
- (2011) Philip B. Gorelick et al. STROKE
- Intrinsic Depot-Specific Differences in the Secretome of Adipose Tissue, Preadipocytes, and Adipose Tissue-Derived Microvascular Endothelial Cells
- (2010) S. L. Hocking et al. DIABETES
- NOX activity in brain aging: Exacerbation by high fat diet
- (2010) Annadora J. Bruce-Keller et al. FREE RADICAL BIOLOGY AND MEDICINE
- High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling
- (2010) Christopher D. Morrison et al. JOURNAL OF NEUROCHEMISTRY
- Surrogate measures of insulin resistance: of rats, mice, and men
- (2009) Kieren Mather AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Cognitive impairment following high fat diet consumption is associated with brain inflammation
- (2009) Paul J. Pistell et al. JOURNAL OF NEUROIMMUNOLOGY
- Age-related differences in inflammatory markers in men: contribution of visceral adiposity
- (2009) Amélie Cartier et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: Contributions of maternal diet
- (2009) Christy L. White et al. NEUROBIOLOGY OF DISEASE
- Adiposity, hyperinsulinemia, diabetes and Alzheimer's disease
- (2008) José Alejandro Luchsinger EUROPEAN JOURNAL OF PHARMACOLOGY
- Effects of short-term Western diet on cerebral oxidative stress and diabetes related factors in APP × PS1 knock-in mice
- (2008) Christa M. Studzinski et al. JOURNAL OF NEUROCHEMISTRY
- The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
- (2008) Berislav V. Zlokovic NEURON
- Obesity and central obesity as risk factors for incident dementia and its subtypes: a systematic review and meta-analysis
- (2008) M. A. Beydoun et al. Obesity Reviews
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started