Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity
Authors
Keywords
-
Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Island Press
Online
2020-04-28
DOI
10.1038/s41467-020-15887-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors
- (2020) Jordan L. Doman et al. NATURE BIOTECHNOLOGY
- Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
- (2019) Julian Grünewald et al. NATURE
- CRISPR DNA base editors with reduced RNA off-target and self-editing activities
- (2019) Julian Grünewald et al. NATURE BIOTECHNOLOGY
- Targeting specificity of APOBEC-based cytosine base editor in human iPSCs determined by whole genome sequencing
- (2019) Erica McGrath et al. Nature Communications
- Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors
- (2019) Beau R. Webber et al. Nature Communications
- Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction
- (2018) Luke W Koblan et al. NATURE BIOTECHNOLOGY
- Base editing: precision chemistry on the genome and transcriptome of living cells
- (2018) Holly A. Rees et al. NATURE REVIEWS GENETICS
- Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
- (2017) Nicole M. Gaudelli et al. NATURE
- Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions
- (2017) Y Bill Kim et al. NATURE BIOTECHNOLOGY
- Differences between germline and somatic mutation rates in humans and mice
- (2017) Brandon Milholland et al. Nature Communications
- Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity
- (2017) Alexis C. Komor et al. Science Advances
- Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
- (2016) Alexis C. Komor et al. NATURE
- Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B
- (2016) Ke Shi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B
- (2016) Ke Shi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- The APOBEC3C crystal structure and the interface for HIV-1 Vif binding
- (2012) Shingo Kitamura et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Evolution of the mutation rate
- (2010) Michael Lynch TRENDS IN GENETICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now