Activation of STAT3 is a key event in TLR4 signaling-mediated melanoma progression

A TCM formula comprising Sophorae Flos and Lonicerae Japonicae Flos alters compositions of immune cells and molecules of the STAT3 pathway in melanoma microenvironment

(2019) Yu-Xi Liu et al.   PHARMACOLOGICAL RESEARCH

BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival

(2019) Erinna F. Lee et al.   Cell Death & Disease

Induction of Pro-Inflammatory Response via Activated Macrophage-Mediated NF-κB and STAT3 Pathways in Gastric Cancer Cells

(2018) Yujuan Zhou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Parthenolide Inhibits STAT3 Signaling by Covalently Targeting Janus Kinases

(2018) Man Liu et al.   MOLECULES

Alteration of the Antitumor Immune Response by Cancer-Associated Fibroblasts

(2018) Linda Ziani et al.   Frontiers in Immunology

Hypaphorine Attenuates Lipopolysaccharide-Induced Endothelial Inflammation via Regulation of TLR4 and PPAR-γ Dependent on PI3K/Akt/mTOR Signal Pathway

(2017) Haijian Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Promising Targets for Cancer Immunotherapy: TLRs, RLRs, and STING-Mediated Innate Immune Pathways

(2017) Kai Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibiting STAT3 signaling is involved in the anti-melanoma effects of a herbal formula comprising Sophorae Flos and Lonicerae Japonicae Flos

(2017) Ting Li et al.   Scientific Reports

Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis

(2017) Daffolyn Rachael Fels Elliott et al.   PLoS Genetics

In Vitro Modeling of Tumor–Immune System Interaction

(2017) Chantal Mengus et al.   ACS Biomaterials-Science & Engineering

Expression of TLR4 in Non-Small Cell Lung Cancer Is Associated with PD-L1 and Poor Prognosis in Patients Receiving Pulmonectomy

(2017) Kaiyuan Wang et al.   Frontiers in Immunology

In Vitro Modeling of Tumor–Immune System Interaction

(2017) Chantal Mengus et al.   ACS Biomaterials Science & Engineering

Parthenolide inhibits LPS-induced inflammatory cytokines through the toll-like receptor 4 signal pathway in THP-1 cells

(2015) S. Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

(2015) Douglas Marvel et al.   JOURNAL OF CLINICAL INVESTIGATION

Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion

(2015) Hui-Hui Cao et al.   Molecular Cancer

TLR4 signaling promotes a COX-2/PGE2/STAT3 positive feedback loop in hepatocellular carcinoma (HCC) cells

(2015) Ang Lin et al.   OncoImmunology

Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis

(2014) S. Boettcher et al.   BLOOD

Enhancement of T cell recruitment and infiltration into tumours

(2014) C. Oelkrug et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Dual Signaling of MyD88 and TRIF Is Critical for Maximal TLR4-Induced Dendritic Cell Maturation

(2014) H. Shen et al.   JOURNAL OF IMMUNOLOGY

TLR4 Ligands Induce IFN-  Production by Mouse Conventional Dendritic Cells and Human Monocytes after IFN-  Priming

(2014) C. Richez et al.   JOURNAL OF IMMUNOLOGY

Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma

(2014) Tobias Bald et al.   NATURE

Toll-Like Receptor 4 Signaling Promotes the Migration of Human Melanoma Cells

(2014) Yuko Takazawa et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Platelets promote tumour metastasis via interaction between TLR4 and tumour cell-released high-mobility group box1 protein

(2014) Le-Xing Yu et al.   Nature Communications

Toll-Like Receptor Signaling Pathways

(2014) Takumi Kawasaki et al.   Frontiers in Immunology

STAT3 Target Genes Relevant to Human Cancers

(2014) Richard Carpenter et al.   Cancers

Quercetin exerts anti-melanoma activities and inhibits STAT3 signaling

(2013) Hui-Hui Cao et al.   BIOCHEMICAL PHARMACOLOGY

TLR4 Mediates MAPK–STAT3 Axis Activation in Bladder Epithelial Cells

(2013) Huang Ying et al.   INFLAMMATION

SOCS3 Expression Correlates with Severity of Inflammation, Expression of Proinflammatory Cytokines, and Activation of STAT3 and p38 MAPK in LPS-Induced InflammationIn Vivo

(2013) João Antônio Chaves de Souza et al.   MEDIATORS OF INFLAMMATION

Toll-Like Receptor 4 Activation in Cancer Progression and Therapy

(2011) Alja Oblak et al.   Clinical & Developmental Immunology

Cell context-dependent activities of parthenolide in primary and metastatic melanoma cells

(2010) M Czyz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Toll-like Receptor 9 Activation of Signal Transducer and Activator of Transcription 3 Constrains Its Agonist-Based Immunotherapy

(2009) M. Kortylewski et al.   CANCER RESEARCH

Stat3 promotes the development of erythroleukemia by inducing Pu.1 expression and inhibiting erythroid differentiation

(2009) S Hegde et al.   ONCOGENE

New insights of epithelial-mesenchymal transition in cancer metastasis

(2008) Yadi Wu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

ICAM-1 Has a Critical Role in the Regulation of Metastatic Melanoma Tumor Susceptibility to CTL Lysis by Interfering with PI3K/AKT Pathway

(2008) A. Hamai et al.   CANCER RESEARCH

Activation of toll-like receptors 2, 3, and 4 on human melanoma cells induces inflammatory factors

(2008) Y. Goto et al.   MOLECULAR CANCER THERAPEUTICS