N-Heterocyclic Carbene Ligand-Enabled C(sp3 )−H Arylation of Piperidine and Tetrahydropyran Derivatives

Regio- and Stereoselective Pd-Catalyzed Direct Arylation of Unactivated sp3 C(3)–H Bonds of Tetrahydrofuran and 1,4-Benzodioxane Systems

(2015) Ramarao Parella et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct α-Arylation of Ethers through the Combination of Photoredox-Mediated CH Functionalization and the Minisci Reaction

(2014) Jian Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-N-Heterocyclic Carbene (NHC)-Catalyzed Asymmetric Synthesis of Indolines through Regiodivergent C(sp3)H Activation: Scope and DFT Study

(2014) Dmitry Katayev et al.   CHEMISTRY-A EUROPEAN JOURNAL

Efficient Synthesis ofcis-3-Substituted Prolines by Bidentate-Assisted Palladium Catalysis

(2014) Ruokun Feng et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene-Palladium(II)-1-Methylimidazole Complex-Catalyzed Direct C–H Bond Arylation of (Benz)imidazoles with Aryl Chlorides

(2014) Zheng-Song Gu et al.   JOURNAL OF ORGANIC CHEMISTRY

Ligand-Promoted Alkylation of C(sp3)–H and C(sp2)–H Bonds

(2014) Ru-Yi Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

Direct C–H Bond Arylation of (Benzo)oxazoles with Aryl Chlorides Catalyzed by N-Heterocyclic Carbene–Palladium(II)–1-Methylimidazole Complex

(2014) Xiao-Bao Shen et al.   ORGANIC LETTERS

Regio- and Stereospecific Synthesis of C-3 Functionalized Proline Derivatives by Palladium Catalyzed Directed C(sp3)–H Arylation

(2014) Dominic P. Affron et al.   ORGANIC LETTERS

Ligand-Controlled C(sp3)-H Arylation and Olefination in Synthesis of Unnatural Chiral  -Amino Acids

(2014) J. He et al.   SCIENCE

Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups

(2013) Guy Rouquet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalyst-Controlled Divergent C–H Functionalization of Unsymmetrical 2-Aryl Cyclic 1,3-Dicarbonyl Compounds with Alkynes and Alkenes

(2013) Johnathon D. Dooley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium(0)-Catalyzed Alkynylation of C(sp3)–H Bonds

(2013) Jian He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Unactivated Methylene C(sp3)–H Bonds with Primary Alkyl Halides

(2013) Shu-Yu Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed Oxidative C(3)–H Functionalization of Amines

(2013) Noriaki Takasu et al.   ORGANIC LETTERS

Ligand-controlled β-selective C(sp3)–H arylation of N-Boc-piperidines

(2013) Anthony Millet et al.   Chemical Science

Scope and mechanism of asymmetric C(sp3)–H/C(Ar)–X coupling reactions: computational and experimental study

(2013) Evgeny Larionov et al.   Chemical Science

Iridium-Catalyzed Oxidant-Free Dehydrogenative CH Bond Functionalization: Selective Preparation of N-Arylpiperidines through Tandem Hydrogen Transfers

(2012) Kedong Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonnatural Amino Acid Synthesis by Using Carbon-Hydrogen Bond Functionalization Methodology

(2012) Ly Dieu Tran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Providing Support in Favor of the Existence of a PdII/PdIVCatalytic Cycle in a Heck-Type Reaction

(2012) Francisco Juliá-Hernández et al.   CHEMISTRY-A EUROPEAN JOURNAL

Isoquinoline Derivatives via Stepwise Regioselective sp2 and sp3 C–H Bond Functionalizations

(2012) Tarek Boudiar et al.   JOURNAL OF ORGANIC CHEMISTRY

Ligand-Enabled Methylene C(sp3)–H Bond Activation with a Pd(II) Catalyst

(2012) Masayuki Wasa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Pd-Catalyzed Direct Arylations of Heterocycles with Unreactive and Hindered Aryl Chlorides

(2012) Debalina Ghosh et al.   ORGANIC LETTERS

Asymmetric C(sp3)-H/C(Ar) coupling reactions. Highly enantio-enriched indolines via regiodivergent reaction of a racemic mixture

(2012) Dmitry Katayev et al.   Chemical Science

Synthesis of a Palladium(IV) Complex by Oxidative Addition of an Aryl Halide to Palladium(II) and Its Use as Precatalyst in a CC Coupling Reaction

(2011) José Vicente et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fused Indolines by Palladium-Catalyzed Asymmetric CC Coupling Involving an Unactivated Methylene Group

(2011) Masafumi Nakanishi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety

(2011) Nicholas A. Meanwell   CHEMICAL RESEARCH IN TOXICOLOGY

Transition metal-catalyzed arylation of unactivated C(sp3)–H bonds

(2011) Olivier Baudoin   CHEMICAL SOCIETY REVIEWS

sp3C–H Bond Activation with Ruthenium(II) Catalysts and C(3)-Alkylation of Cyclic Amines

(2011) Basker Sundararaju et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis and Structural Revision of the Piperarborenines via Sequential Cyclobutane C–H Arylation

(2011) Will R. Gutekunst et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene Palladium Catalyzed Regioselective Oxidative Trifluoroacetoxylation of Unactivated Methylene sp3C–H Bonds in Linear Alkyl Esters

(2011) Xiu-Feng Hou et al.   ORGANOMETALLICS

Discovery of an  -Amino C-H Arylation Reaction Using the Strategy of Accelerated Serendipity

(2011) A. McNally et al.   SCIENCE

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Functionalization of Organic Molecules by Transition-Metal-Catalyzed C(sp3)H Activation

(2010) Rodolphe Jazzar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cross-Coupling of C(sp3)-H Bonds with Organometallic Reagents via Pd(II)/Pd(0) Catalysis

(2010) Masayuki Wasa et al.   ISRAEL JOURNAL OF CHEMISTRY

A Graphical Journey of Innovative Organic Architectures That Have Improved Our Lives

(2010) Nicholas A. McGrath et al.   JOURNAL OF CHEMICAL EDUCATION

Platinum-Catalyzed Michael Addition and Cyclization of Tertiary Amines with Nitroolefins by Dehydrogenation of α,β-sp3C−H Bonds

(2010) Xiao-Feng Xia et al.   JOURNAL OF ORGANIC CHEMISTRY

Iron-Catalyzed C−C Bond Formation at α-Position of Aliphatic Amines via C−H Bond Activation through 1,5-Hydrogen Transfer

(2010) Naohiko Yoshikai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp2and sp3Carbon−Hydrogen Bonds

(2010) Dmitry Shabashov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium- and Copper-Catalyzed Arylation of Carbon−Hydrogen Bonds

(2009) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Total Synthesis of Celogentin C by Stereoselective CH Activation

(2009) Yiqing Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fe-Catalyzed Oxidative Coupling of Heteroarenes and Methylamines

(2009) Masaki Ohta et al.   Chemistry-An Asian Journal

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chelating N-Heterocyclic Carbene Alkoxide as a Supporting Ligand for PdII/IVC−H Bond Functionalization Catalysis

(2009) Polly L. Arnold et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(0)/PR3-Catalyzed Intermolecular Arylation of sp3C−H Bonds

(2009) Masayuki Wasa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Well-Defined N-Heterocyclic Carbenes−Palladium(II) Precatalysts for Cross-Coupling Reactions

(2008) Nicolas Marion et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enantioselective Pd-Catalyzed α-Arylation ofN-Boc-Pyrrolidine: The Key to an Efficient and Practical Synthesis of a Glucokinase Activator

(2008) Artis Klapars et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd(II)-Catalyzed Cross-Coupling of sp3C−H Bonds with sp2and sp3Boronic Acids Using Air as the Oxidant

(2008) Dong-Hui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Versatile Pd(II)-Catalyzed C−H Activation/Aryl−Aryl Coupling of Benzoic and Phenyl Acetic Acids

(2008) Dong-Hui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY