Scope and mechanism of asymmetric C(sp3)–H/C(Ar)–X coupling reactions: computational and experimental study

Atropoisomeric (P,N) Ligands for the Highly Enantioselective Pd-Catalyzed Intramolecular Asymmetric α-Arylation of α-Branched Aldehydes

(2012) Pradeep Nareddy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Monodentate Phosphines and Bulky Carboxylic Acids: Cooperative Effects in Palladium-Catalyzed Enantioselective C(sp3)-H Functionalization

(2012) Tanguy Saget et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective palladium-catalyzed direct cross-coupling of coumarins with simple arenes

(2012) Minsik Min et al.   CHEMICAL COMMUNICATIONS

A facile route to isoflavone quinones via the direct cross-coupling of chromones and quinones

(2012) Youngtaek Moon et al.   CHEMICAL COMMUNICATIONS

Diastereo- and Enantioselective Intramolecular C(sp3)H Arylation for the Synthesis of Fused Cyclopentanes

(2012) Nicolas Martin et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-NHC Catalyzed Enantioselective Synthesis of Fused Indolines via Inert C(sp3)-H Activation

(2012) Masafumi Nakanishi et al.   CHIMIA

Catalytic Enantioselective Synthesis of a 3-Aryl-3-benzyloxindole (=3-Aryl-3-benzyl-1,3-dihydro-2H-indol-2-one) Exhibiting Antitumor Activity

(2012) Dmitry Katayev et al.   HELVETICA CHIMICA ACTA

Mechanistic Studies on Direct Arylation of Pyridine N-Oxide: Evidence for Cooperative Catalysis between Two Distinct Palladium Centers

(2012) Yichen Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral N-Heterocyclic Carbene Borane Complexes: Synthesis and Structural Analysis

(2012) Dipshikha Banerjee et al.   ORGANOMETALLICS

Chiral Monodentate Trialkylphosphines Based on the Phospholane Architecture

(2012) Pavel A. Donets et al.   ORGANOMETALLICS

Chiral N-Heterocyclic Carbene Gold Complexes: Synthesis, Properties, and Application in Asymmetric Catalysis

(2012) Dipshikha Banerjee et al.   ORGANOMETALLICS

Asymmetric C(sp3)-H/C(Ar) coupling reactions. Highly enantio-enriched indolines via regiodivergent reaction of a racemic mixture

(2012) Dmitry Katayev et al.   Chemical Science

Fused Indolines by Palladium-Catalyzed Asymmetric CC Coupling Involving an Unactivated Methylene Group

(2011) Masafumi Nakanishi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective synthesis of 2-methyl indolines by palladium catalysed asymmetric C(sp3)–H activation/cyclisation

(2011) Saithalavi Anas et al.   CHEMICAL COMMUNICATIONS

Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope

(2011) Lutz Ackermann   CHEMICAL REVIEWS

Transition metal-catalyzed arylation of unactivated C(sp3)–H bonds

(2011) Olivier Baudoin   CHEMICAL SOCIETY REVIEWS

Recent advances in the transition metal-catalyzed twofold oxidative C–H bond activation strategy for C–C and C–N bond formation

(2011) Seung Hwan Cho et al.   CHEMICAL SOCIETY REVIEWS

Amination with Pd-NHC Complexes: Rate and Computational Studies on the Effects of the Oxidative Addition Partner

(2011) Ka Hou Hoi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nickel-Catalyzed Alkyl Coupling Reactions: Evaluation of Computational Methods

(2011) Lawrence M. Pratt et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Assessment of the Intermediacy of Arylpalladium Carboxylate Complexes in the Direct Arylation of Benzene: Evidence for C−H Bond Cleavage by “Ligandless” Species

(2011) Yichen Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzed Enantioselective C–H Activation of Cyclopropanes

(2011) Masayuki Wasa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Mediated Intermolecular Direct Biaryl Coupling

(2011) Masanori Kitahara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium(II)-Catalyzed Direct Alkoxylation of Arenes: Evidence for Solvent-Assisted Concerted Metalation Deprotonation

(2011) Megha Anand et al.   ORGANIC LETTERS

Palladium(II)-Catalyzed Direct Intermolecular Alkenylation of Chromones

(2011) Donghee Kim et al.   ORGANIC LETTERS

Palladium(0)-catalyzed cyclopropane C–H bond functionalization: synthesis of quinoline and tetrahydroquinoline derivatives

(2011) Sophie Rousseaux et al.   Chemical Science

Challenge and progress: palladium-catalyzed sp3 C–H activation

(2011) Hu Li et al.   Catalysis Science & Technology

Palladium-Catalyzed β Arylation of Carboxylic Esters

(2010) Alice Renaudat et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C—H Bond Activation in Transition Metal Species from a Computational Perspective

(2010) David Balcells et al.   CHEMICAL REVIEWS

Overview of the Mechanistic Work on the Concerted Metallation–Deprotonation Pathway

(2010) David Lapointe et al.   CHEMISTRY LETTERS

New Chiral N-Heterocyclic Carbene Ligands in Palladium-Catalyzed α-Arylations of Amides: Conformational Locking through Allylic Strain as a Device for Stereocontrol

(2010) Yi-Xia Jia et al.   CHEMISTRY-A EUROPEAN JOURNAL

Functionalization of Organic Molecules by Transition-Metal-Catalyzed C(sp3)H Activation

(2010) Rodolphe Jazzar et al.   CHEMISTRY-A EUROPEAN JOURNAL

DFT study of the mechanism of benzocyclobutene formation by palladium-catalysed C(sp3)–H activation: role of the nature of the base and the phosphine

(2010) Christos E. Kefalidis et al.   DALTON TRANSACTIONS

Modulating Reactivity and Diverting Selectivity in Palladium-Catalyzed Heteroaromatic Direct Arylation Through the Use of a Chloride Activating/Blocking Group

(2010) Benoît Liégault et al.   JOURNAL OF ORGANIC CHEMISTRY

Assessing the Performance of Density Functional Theory for the Electronic Structure of Metal−Salens: The M06 Suite of Functionals and the d4-Metals

(2010) Tait Takatani et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Structure and Bonding of Isoleptic Coinage Metal (Cu, Ag, Au) Dimethylaminonitrenes in the Gas Phase

(2010) Alexey Fedorov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Controlled Regioselectivity in Palladium-Catalyzed Cross Coupling Reactions

(2010) Franziska Schoenebeck et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intramolecular Palladium-Catalyzed Alkane C−H Arylation from Aryl Chlorides

(2010) Sophie Rousseaux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Investigation of the Mechanism of C(sp3)−H Bond Cleavage in Pd(0)-Catalyzed Intramolecular Alkane Arylation Adjacent to Amides and Sulfonamides

(2010) Sophie Rousseaux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in aryl–aryl bond formation by direct arylation

(2009) Gerard P. McGlacken et al.   CHEMICAL SOCIETY REVIEWS

Transition metal-catalyzed C–H activation reactions: diastereoselectivity and enantioselectivity

(2009) Ramesh Giri et al.   CHEMICAL SOCIETY REVIEWS

Density Functional Theory Investigation of the Alkyl-Alkyl Negishi Cross-Coupling Reaction Catalyzed by N-Heterocyclic Carbene (NHC)-Pd Complexes

(2009) Gregory A. Chass et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mechanisms of C–H bond activation: rich synergy between computation and experiment

(2009) Youcef Boutadla et al.   DALTON TRANSACTIONS

Noncovalent Interactions in a Transition-Metal Triphenylphosphine Complex: a Density Functional Case Study†

(2009) Nicolas Sieffert et al.   INORGANIC CHEMISTRY

Establishment of Broadly Applicable Reaction Conditions for the Palladium-Catalyzed Direct Arylation of Heteroatom-Containing Aromatic Compounds

(2009) Benoît Liégault et al.   JOURNAL OF ORGANIC CHEMISTRY

Cycloadditions of 1,1-Disubstituted Benzocyclobutenes Obtained by C(sp3)−H Activation

(2009) Manon Chaumontet et al.   JOURNAL OF ORGANIC CHEMISTRY

Metal−Phosphine Bond Strengths of the Transition Metals: A Challenge for DFT†

(2009) Yury Minenkov et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Conformations of N-Heterocyclic Carbene Ligands in Ruthenium Complexes Relevant to Olefin Metathesis

(2009) Ian C. Stewart et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Activation of an Alkyl C−H Bond Geminal to an Agostic Interaction: An Unusual Mode of Base-Induced C−H Activation

(2009) L. Jonas L. Häller et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of Ligand Steric Properties and Halide Identity on the Mechanism for Oxidative Addition of Haloarenes to Trialkylphosphine Pd(0) Complexes

(2009) Fabiola Barrios-Landeros et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Efficient Process for Pd-Catalyzed C−N Cross-Coupling Reactions of Aryl Iodides: Insight Into Controlling Factors

(2009) Brett P. Fors et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformational Analysis of Olefin−Carbene Ruthenium Metathesis Catalysts

(2009) Diego Benitez et al.   ORGANOMETALLICS

Recent advances in the synthesis of (hetero)aryl-substituted heteroarenes via transition metal-catalysed direct (hetero)arylation of heteroarene C–H bonds with aryl halides or pseudohalides, diaryliodonium salts, and potassium aryltrifluoroborates

(2009) Fabio Bellina et al.   TETRAHEDRON

Density Functionals with Broad Applicability in Chemistry

(2008) Yan Zhao et al.   ACCOUNTS OF CHEMICAL RESEARCH

PdII-Catalyzed Enantioselective Activation of C(sp2)H and C(sp3)H Bonds Using Monoprotected Amino Acids as Chiral Ligands

(2008) Bing-Feng Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of 3,4-Dihydroisoquinolines by a C(sp3)H Activation/Electrocyclization Strategy: Total Synthesis of Coralydine

(2008) Manon Chaumontet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral N-heterocyclic carbene ligands for asymmetric catalytic oxindole synthesis

(2008) Yi-Xia Jia et al.   CHEMICAL COMMUNICATIONS

Analysis of the Concerted Metalation-Deprotonation Mechanism in Palladium-Catalyzed Direct Arylation Across a Broad Range of Aromatic Substrates

(2008) Serge I. Gorelsky et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Benzocyclobutenes by Palladium-Catalyzed C−H Activation of Methyl Groups: Method and Mechanistic Study

(2008) Manon Chaumontet et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion

(2008) Huw M. L. Davies et al.   NATURE

Palladium-Catalyzed Direct Arylation of Nitro-Substituted Aromatics with Aryl Halides

(2008) Laurence Caron et al.   ORGANIC LETTERS

Palladium-Catalyzed sp3CH Activation of Simple Alkyl Groups: Direct Preparation of Indoline Derivatives fromN-Alkyl-2-bromoanilines

(2008) Toshiaki Watanabe et al.   ORGANIC LETTERS

Assisted Ruthenium-Catalyzed C−H Bond Activation: Carboxylic Acids as Cocatalysts for Generally Applicable Direct Arylations in Apolar Solvents

(2008) Lutz Ackermann et al.   ORGANIC LETTERS

Pd-NHC (PEPPSI) Complexes: Synthetic Utility and Computational Studies into Their Reactivity

(2008) Michael Organ et al.   SYNTHESIS-STUTTGART

Mild and efficient palladium-catalyzed intramolecular direct arylation reactions

(2008) Marc Lafrance et al.   TETRAHEDRON

Bidentate phosphines as ligands in the palladium-catalyzed intramolecular arylation: the intermolecular base-assisted proton abstraction mechanism

(2008) Sergio Pascual et al.   TETRAHEDRON