Blocking the death checkpoint protein TRAIL improves cardiac function after myocardial infarction in monkeys, pigs, and rats

Dectin-1 Contributes to Myocardial Ischemia/Reperfusion Injury by Regulating Macrophage Polarization and Neutrophil Infiltration

(2019) Qin Fan et al.   CIRCULATION

Multiple Interactions Between Cancer Cells and the Tumor Microenvironment Modulate TRAIL Signaling: Implications for TRAIL Receptor Targeted Therapy

(2019) Margot de Looff et al.   Frontiers in Immunology

Targeting Chondroitin Sulfate Glycosaminoglycans to Treat Cardiac Fibrosis in Pathological Remodeling

(2018) Rong-Rong Zhao et al.   CIRCULATION

Regulation of TNF-Related Apoptosis-Inducing Ligand Signaling by Glycosylation

(2018) Olivier Micheau   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial

(2018) Paul M Ridker et al.   LANCET

Translational overview of cytokine inhibition in acute myocardial infarction and chronic heart failure

(2018) Minke H.T. Hartman et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Circulating proteins as predictors of incident heart failure in the elderly

(2017) Markus Stenemo et al.   EUROPEAN JOURNAL OF HEART FAILURE

Effect of interleukin-6 inhibition on coronary microvascular and endothelial function in myocardial infarction

(2017) Espen Holte et al.   HEART

Akuter Myokardinfarkt bei Patienten mit ST-Strecken-Hebungs-Infarkt

(2017) H. Thiele et al.   HERZ

TRAIL facilitates cytokine expression and macrophage migration during hypoxia/reoxygenation via ER stress-dependent NF-κB pathway

(2017) Yinan Jiang et al.   MOLECULAR IMMUNOLOGY

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

GDF-15 and TRAIL-R2 are powerful predictors of long-term mortality in patients with acute myocardial infarction

(2017) Emma Skau et al.   European Journal of Preventive Cardiology

Inflammatory Biomarkers Predict Heart Failure Severity and Prognosis in Patients With Heart Failure With Preserved Ejection FractionCLINICAL PERSPECTIVE

(2017) Camilla Hage et al.   Circulation-Cardiovascular Genetics

TRAIL restores DCA/metformin-mediated cell death in hypoxia

(2016) Sung-Eun Hong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cellular recruitment in myocardial ischaemia/reperfusion injury

(2016) Aldo Bonaventura et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Treatment with anti-RANKL antibody reduces infarct size and attenuates dysfunction impacting on neutrophil-mediated injury

(2016) Federico Carbone et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction

(2016) Hendrik B. Sager et al.   Science Translational Medicine

Vascular calcification in type-2 diabetes and cardiovascular disease: Integrative roles for OPG, RANKL and TRAIL

(2016) Emma Harper et al.   VASCULAR PHARMACOLOGY

Roles and Clinical Applications of OPG and TRAIL as Biomarkers in Cardiovascular Disease

(2016) Stella Bernardi et al.   Biomed Research International

Effects of the P‐Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention According to Timing of Infusion: Insights From the SELECT‐ACS Trial

(2016) Barbara E. Stähli et al.   Journal of the American Heart Association

Hsf4 counteracts Hsf1 transcription activities and increases lens epithelial cell survival in vitro

(2015) Xiukun Cui et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome

(2015) Yiqing Yan et al.   CELL

Anti-CCL21 Antibody Attenuates Infarct Size and Improves Cardiac Remodeling After Myocardial Infarction

(2015) Yi Jiang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Insulin promotes vascular smooth muscle cell proliferation and apoptosis via differential regulation of tumor necrosis factor-related apoptosis-inducing ligand

(2015) Hanis H. Harith et al.   Journal of Diabetes

Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Promotes Angiogenesis and Ischemia-Induced Neovascularization Via NADPH Oxidase 4 (NOX4) and Nitric Oxide-Dependent Mechanisms

(2015) B. A. Di Bartolo et al.   Journal of the American Heart Association

Tumor necrosis factor-related apoptosis-inducing ligand in vascular inflammation and atherosclerosis: A protector or culprit?

(2014) Wen Cheng et al.   VASCULAR PHARMACOLOGY

Burden of Cardiovascular Morbidity and Mortality Following Humanitarian Emergencies: A Systematic Literature Review

(2014) Kaitlin G. Hayman et al.   Prehospital and Disaster Medicine

Cardiovascular effects of tumour necrosis factor α antagonism in patients with acute myocardial infarction: a first in human study

(2013) Gareth J Padfield et al.   HEART

Temporal dynamics of cardiac immune cell accumulation following acute myocardial infarction

(2013) Xiaoxiang Yan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Heritable gene targeting in the mouse and rat using a CRISPR-Cas system

(2013) Dali Li et al.   NATURE BIOTECHNOLOGY

Prognostic Value of TNF-Related Apoptosis Inducing Ligand (TRAIL) in Acute Coronary Syndrome Patients

(2013) Pavel Osmancik et al.   PLoS One

Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells

(2011) Lianchun Fan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Electrocardiographic Characterization of Rhesus Monkey Model of Ischemic Myocardial Infarction Induced by Left Anterior Descending Artery Ligation

(2011) Pingliang Yang et al.   Cardiovascular Toxicology

Cell Death Pathways in Acute Ischemia/Reperfusion Injury

(2011) Roberta A. Gottlieb   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Methods in cardiomyocyte isolation, culture, and gene transfer

(2011) William E. Louch et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Reduction of neutrophil activity decreases early microvascular injury after subarachnoid haemorrhage

(2011) Victor Friedrich et al.   Journal of Neuroinflammation

Metalloproteinase 2 cleaves in vitro recombinant TRAIL: Potential implications for the decreased serum levels of TRAIL after acute myocardial infarction

(2010) Paola Secchiero et al.   ATHEROSCLEROSIS

Hypoxia inducing factor-1α regulates tumor necrosis factor-related apoptosis-inducing ligand sensitivity in tumor cells exposed to hypoxia

(2010) Jae-Kyo Jeong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRAIL Promotes VSMC Proliferation and Neointima Formation in a FGF-2–, Sp1 Phosphorylation–, and NFκB-Dependent Manner

(2010) Jeffrey Chan et al.   CIRCULATION RESEARCH

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces chemotactic migration of monocytes via a death receptor 4-mediated RhoGTPase pathway

(2010) Wei Wei et al.   MOLECULAR IMMUNOLOGY

Depletion of macrophages in mice results in higher dengue virus titers and highlights the role of macrophages for virus control

(2009) Katja Fink et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Potential Prognostic Significance of Decreased Serum Levels of TRAIL after Acute Myocardial Infarction

(2009) Paola Secchiero et al.   PLoS One

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced chemokine release in both TRAIL-resistant and TRAIL-sensitive cells via nuclear factor kappa B

(2008) Wanhu Tang et al.   FEBS Journal