Activation of alpha7 nicotinic and NMDA receptors is necessary for performance in a working memory task

Combining CDP-choline and galantamine: Effects of a selective α7 nicotinic acetylcholine receptor agonist strategy on P50 sensory gating of speech sounds in healthy volunteers

(2019) Joelle Choueiry et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Does kynurenic acid act on nicotinic receptors? An assessment of the evidence

(2019) Trevor W. Stone   JOURNAL OF NEUROCHEMISTRY

Cognitive remediation and functional improvement in schizophrenia: Is it a matter of size?

(2017) M. Bosia et al.   EUROPEAN PSYCHIATRY

Preferential Disruption of Prefrontal GABAergic Function by Nanomolar Concentrations of the α7nACh Negative Modulator Kynurenic Acid

(2017) Eden Flores-Barrera et al.   JOURNAL OF NEUROSCIENCE

3-Furan-2-yl- N - p -tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic receptor, reverses schizophrenia-like cognitive and social deficits in rats

(2017) Agnieszka Potasiewicz et al.   NEUROPHARMACOLOGY

Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex

(2017) D.M. Bortz et al.   NEUROPHARMACOLOGY

The kynurenine pathway and the brain: Challenges, controversies and promises

(2017) Robert Schwarcz et al.   NEUROPHARMACOLOGY

The positive allosteric modulator of α7 nicotinic acetylcholine receptors, 3-furan-2-yl-N-p-tolyl-acrylamide, enhances memory processes and stimulates ERK1/2 phosphorylation in mice

(2016) Katarzyna M. Targowska-Duda et al.   BEHAVIOURAL BRAIN RESEARCH

Neurocognitive profile in major depressive disorders: relationship to symptom level and subjective memory complaints

(2016) Christine Mohn et al.   BMC Psychiatry

Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content

(2016) Hugo R. Arias et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Integration of inhibitory and excitatory effects of α7 nicotinic acetylcholine receptor activation in the prelimbic cortex regulates network activity and plasticity

(2016) Matthew Udakis et al.   NEUROPHARMACOLOGY

Second-generation antipsychotic effect on cognition in patients with schizophrenia-a meta-analysis of randomized clinical trials

(2015) R. E. Nielsen et al.   ACTA PSYCHIATRICA SCANDINAVICA

Pro-cognitive activity in rats of 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic acetylcholine receptor

(2015) A. Potasiewicz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Glutamate and dopamine in schizophrenia: An update for the 21st century

(2015) Oliver Howes et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Altered hippocampal plasticity by prenatal kynurenine administration, kynurenine-3-monoxygenase (KMO) deletion or galantamine

(2015) C.M. Forrest et al.   NEUROSCIENCE

Endogenous kynurenic acid regulates extracellular GABA levels in the rat prefrontal cortex

(2014) Sarah Beggiato et al.   NEUROPHARMACOLOGY

Investigating Glutamatergic Mechanism in Attention and Impulse Control Using Rats in a Modified 5-Choice Serial Reaction Time Task

(2014) Abigail Benn et al.   PLoS One

Restoring long-term potentiation impaired by amyloid-beta oligomers: Comparison of an acetylcholinesterase inhibitior and selective neuronal nicotinic receptor agonists

(2013) Katja S. Kroker et al.   BRAIN RESEARCH BULLETIN

The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders

(2013) Trevor W Stone et al.   BRITISH JOURNAL OF PHARMACOLOGY

Kynurenic acid, by targeting α7 nicotinic acetylcholine receptors, modulates extracellular GABA levels in the rat striatumin vivo

(2013) Sarah Beggiato et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Imaging glutamate in schizophrenia: review of findings and implications for drug discovery

(2013) E M P Poels et al.   MOLECULAR PSYCHIATRY

Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: Implications for neuropsychiatric diseases

(2013) Hong Lin et al.   NEUROBIOLOGY OF DISEASE

Early developmental elevations of brain kynurenic acid impair cognitive flexibility in adults: Reversal with galantamine

(2013) K.S. Alexander et al.   NEUROSCIENCE

Comorbid substance use disorder in schizophrenia: A selective overview of neurobiological and cognitive underpinnings

(2013) Patrizia Thoma et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

α7nAchR/NMDAR coupling affects NMDAR function and object recognition

(2013) Shupeng Li et al.   Molecular Brain

Relationship between Glutamate Dysfunction and Symptoms and Cognitive Function in Psychosis

(2013) Kate Merritt et al.   Frontiers in Psychiatry

Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: Facts and challenges

(2012) Edson X. Albuquerque et al.   BIOCHEMICAL PHARMACOLOGY

Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood

(2012) Ana Pocivavsek et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Glutamatergic Synapse Formation is Promoted by  7-Containing Nicotinic Acetylcholine Receptors

(2012) A. F. Lozada et al.   JOURNAL OF NEUROSCIENCE

Facilitation of extinction of operant behaviour in C57Bl/6 mice by chlordiazepoxide and d-cycloserine

(2012) Julian C. Leslie et al.   PSYCHOPHARMACOLOGY

Working memory in the odor span task: effects of chlordiazepoxide, dizocilpine (MK801), morphine, and scopolamine

(2012) Mark Galizio et al.   PSYCHOPHARMACOLOGY

Galantamine increases hippocampal insulin-like growth factor 2 expression via α7 nicotinic acetylcholine receptors in mice

(2012) Yuki Kita et al.   PSYCHOPHARMACOLOGY

D-Cycloserine: An Evolving Role in Learning and Neuroplasticity in Schizophrenia

(2012) D. C. Goff   SCHIZOPHRENIA BULLETIN

Twenty-five Years of Glutamate in Schizophrenia: Are We There Yet?

(2012) D. C. Javitt   SCHIZOPHRENIA BULLETIN

NMDA Receptor Hypofunction, Parvalbumin-Positive Neurons, and Cortical Gamma Oscillations in Schizophrenia

(2012) G. Gonzalez-Burgos et al.   SCHIZOPHRENIA BULLETIN

Effects of D-cycloserine on the extinction of appetitive operant learning.

(2011) Drina Vurbic et al.   BEHAVIORAL NEUROSCIENCE

The chimeric gene CHRFAM7A, a partial duplication of the CHRNA7 gene, is a dominant negative regulator of α7*nAChR function

(2011) Tanguy Araud et al.   BIOCHEMICAL PHARMACOLOGY

Novel Positive Allosteric Modulators of the Human α7 Nicotinic Acetylcholine Receptor

(2011) Hugo R. Arias et al.   BIOCHEMISTRY

Enhanced Control of Attention by Stimulating Mesolimbic-Corticopetal Cholinergic Circuitry

(2011) M. St. Peters et al.   JOURNAL OF NEUROSCIENCE

Fluctuations in Endogenous Kynurenic Acid Control Hippocampal Glutamate and Memory

(2011) Ana Pocivavsek et al.   NEUROPSYCHOPHARMACOLOGY

Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine

(2011) Kathleen S. Alexander et al.   PSYCHOPHARMACOLOGY

Localization by site-directed mutagenesis of a galantamine binding site on α7 nicotinic acetylcholine receptor extracellular domain

(2010) Jürgen Ludwig et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Reduction of Endogenous Kynurenic Acid Formation Enhances Extracellular Glutamate, Hippocampal Plasticity and Cognitive Behavior

(2010) Michelle C Potter et al.   NEUROPSYCHOPHARMACOLOGY

Cortical kynurenic acid bi-directionally modulates prefrontal glutamate levels as assessed by microdialysis and rapid electrochemistry

(2010) Å. Konradsson-Geuken et al.   NEUROSCIENCE

Animal models of cognitive dysfunction and negative symptoms of schizophrenia: Focus on NMDA receptor antagonism

(2010) Joanna C. Neill et al.   PHARMACOLOGY & THERAPEUTICS

Impaired Kynurenine Pathway Metabolism in The Prefrontal Cortex of Individuals With Schizophrenia

(2010) K. V. Sathyasaikumar et al.   SCHIZOPHRENIA BULLETIN

L-kynurenine treatment alters contextual fear conditioning and context discrimination but not cue-specific fear conditioning

(2009) Amy C. Chess et al.   BEHAVIOURAL BRAIN RESEARCH

Neurophysiological and neurochemical animal models of schizophrenia: Focus on glutamate☆

(2009) Stephan Bickel et al.   BEHAVIOURAL BRAIN RESEARCH

Astrocyte-derived kynurenic acid modulates basal and evoked cortical acetylcholine release

(2009) A. Zmarowski et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Glutamate–Dopamine Crosstalk in the Rat Prefrontal Cortex is Modulated by Alpha7 Nicotinic Receptors and Potentiated by PNU-120596

(2009) Phil D. Livingstone et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The Astrocyte-Derived α7 Nicotinic Receptor Antagonist Kynurenic Acid Controls Extracellular Glutamate Levels in the Prefrontal Cortex

(2009) Hui-Qiu Wu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Memory efficiency and the strategic control of attention at encoding: Impairments of value-directed remembering in Alzheimer’s disease.

(2009) Alan D. Castel et al.   NEUROPSYCHOLOGY

Cholinergic Mediation of Attention

(2008) Vinay Parikh et al.   Annals of the New York Academy of Sciences

The Construct of Attention in Schizophrenia

(2008) Steven J. Luck et al.   BIOLOGICAL PSYCHIATRY

Glutamatergic dysfunction in schizophrenia: From basic neuroscience to clinical psychopharmacology

(2008) Rodrigo D. Paz et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Presynaptic  7- and  2-Containing Nicotinic Acetylcholine Receptors Modulate Excitatory Amino Acid Release from Rat Prefrontal Cortex Nerve Terminals via Distinct Cellular Mechanisms

(2008) J. A. Dickinson et al.   MOLECULAR PHARMACOLOGY

Large recurrent microdeletions associated with schizophrenia

(2008) Hreinn Stefansson et al.   NATURE

Facilitation of extinction of operant behaviour in mice by d-cycloserine

(2008) David Shaw et al.   PSYCHOPHARMACOLOGY

CNTRICS Final Task Selection: Control of Attention

(2008) K. H. Nuechterlein et al.   SCHIZOPHRENIA BULLETIN