An integrated pathway interaction network for the combination of four effective compounds from ShengMai preparations in the treatment of cardio-cerebral ischemic diseases

Nrf2 pathway activation contributes to anti-fibrosis effects of ginsenoside Rg1 in a rat model of alcohol- and CCl4-induced hepatic fibrosis

(2014) Jian-ping Li et al.   ACTA PHARMACOLOGICA SINICA

A combination of four active compounds alleviates cerebral ischemia-reperfusion injury in correlation with inhibition of autophagy and modulation of AMPK/mTOR and JNK pathways

(2014) Zhongshun Guo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

A review on the medicinal potentials of ginseng and ginsenosides on cardiovascular diseases

(2014) Chang Ho Lee et al.   Journal of Ginseng Research

The Effect of 17-Methoxyl-7-Hydroxy-Benzene-Furanchalcone on NF-κB and the Inflammatory Response During Myocardial Ischemia Reperfusion Injury in Rats

(2013) Xingmei Liang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Cardioprotective effects of the YiQiFuMai injection and isolated compounds on attenuating chronic heart failure via NF-κB inactivation and cytokine suppression

(2013) Lu Xing et al.   JOURNAL OF ETHNOPHARMACOLOGY

Identification of hepatocellular carcinoma related genes with k-th shortest paths in a protein–protein interaction network

(2013) Min Jiang et al.   Molecular BioSystems

Postnatal administration of IL-1Ra exerts neuroprotective effects following perinatal inflammation and/or hypoxic-ischemic injuries

(2012) Sylvie Girard et al.   BRAIN BEHAVIOR AND IMMUNITY

Carbamate Derivatives of Indolines as Cholinesterase Inhibitors and Antioxidants for the Treatment of Alzheimer’s Disease

(2012) Inessa Yanovsky et al.   JOURNAL OF MEDICINAL CHEMISTRY

Network target for screening synergistic drug combinations with application to traditional Chinese medicine

(2011) Shao Li et al.   BMC Systems Biology

Drug–target network and polypharmacology studies of a Traditional Chinese Medicine for type II diabetes mellitus

(2011) Jiangyong Gu et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Upregulation of heme oxygenase-1 via PI3K/Akt and Nrf-2 signaling pathways mediates the anti-inflammatory activity of Schisandrin in Porphyromonas gingivalis LPS-stimulated macrophages

(2011) Sun Young Park et al.   IMMUNOLOGY LETTERS

Homocysteine induces cardiomyocyte dysfunction and apoptosis through p38 MAPK-mediated increase in oxidant stress

(2011) Xu Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Transient receptor potential vanilloid-1 participates in the inhibitory effect of ginsenoside Rg1 on capsaicin-induced interleukin-8 and prostaglandin E2production in HaCaT cells

(2011) Jin Huang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Suppression of local inflammation contributes to the neuroprotective effect of ginsenoside Rb1 in rats with cerebral ischemia

(2011) J. Zhu et al.   NEUROSCIENCE

Attenuation of NF-κB and activation of Nrf2 signaling by 1,2,4-triazine derivatives, protects neuron-like PC12 cells against apoptosis

(2010) Solaleh Khoramian Tusi et al.   APOPTOSIS

Identification of multiple constituents in the traditional Chinese medicine formula Sheng-Mai San and rat plasma after oral administration by HPLC–DAD–MS/MS

(2010) Yan-Hui Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-κB activation

(2010) Qian Liu et al.   NEUROCHEMISTRY INTERNATIONAL

PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach

(2010) Xiaofeng Liu et al.   NUCLEIC ACIDS RESEARCH

Neuroprotective effect of 5,7,3′,4′,5′-pentahydroxy dihdroflavanol-3-O-(2″-O-galloyl)-β-d-glucopyranoside, a polyphenolic compound in focal cerebral ischemia in rat

(2009) Rathinam ArunaDevi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ginsenoside Rb1 protects against 6-hydroxydopamine-induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K/Akt/Nrf2-dependent pathway in human dopaminergic cells

(2009) Yong Pil Hwang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Walking the Interactome for Prioritization of Candidate Disease Genes

(2008) Sebastian Köhler et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice

(2008) Limei Li et al.   BMC IMMUNOLOGY

Effect of Shengmai injection (生脉注射液) on vascular endothelial and heart functions in patients with coronary heart disease complicated with diabetes mellitus

(2008) Ya-chen Zhang et al.   Chinese Journal of Integrative Medicine

Schizandrin Protects Primary Cultures of Rat Cortical Cells From Glutamate-Induced Excitotoxicity

(2008) Hao-Yuan Cheng et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Brain Oxidative Stress as Basic Target of Antioxidant Traditional Oriental Medicines

(2008) Tetsuya Konishi   NEUROCHEMICAL RESEARCH

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Toll-Like Receptor-4 Coordinates the Innate Immune Response of the Kidney to Renal Ischemia/Reperfusion Injury

(2008) Wilco P. Pulskens et al.   PLoS One