A novel immunocompetent model of metastatic prostate cancer‐induced bone pain

A mouse model of prostate cancer bone metastasis in a syngeneic immunocompetent host

(2019) Brian W. Simons et al.   Oncotarget

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTRin Nociception

(2018) Kijung Sung et al.   JOURNAL OF NEUROSCIENCE

Translational models of prostate cancer bone metastasis

(2018) Richard B. Berish et al.   Nature Reviews Urology

Absence of myeloid Klf4 reduces prostate cancer growth with pro-atherosclerotic activation of tumor myeloid cells and infiltration of CD8 T cells

(2018) David J. Barakat et al.   PLoS One

Cytotoxic T cells modulate inflammation and endogenous opioid analgesia in chronic arthritis

(2017) Uta Baddack-Werncke et al.   Journal of Neuroinflammation

Selective Inhibition of Trigeminovascular Neurons by Fremanezumab: A Humanized Monoclonal Anti-CGRP Antibody

(2017) Agustin Melo-Carrillo et al.   JOURNAL OF NEUROSCIENCE

The role of calcitonin gene–related peptide in peripheral and central pain mechanisms including migraine

(2017) Smriti Iyengar et al.   PAIN

Deletion of Runx2 in Articular Chondrocytes Decelerates the Progression of DMM-Induced Osteoarthritis in Adult Mice

(2017) Lifan Liao et al.   Scientific Reports

Effect of estrogen on morphine- and oxycodone-induced antinociception in a female femur bone cancer pain model

(2016) Hiroko Ono et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Induction of Migraine-Like Photophobic Behavior in Mice by Both Peripheral and Central CGRP Mechanisms

(2016) Bianca N. Mason et al.   JOURNAL OF NEUROSCIENCE

Elevated levels of calcitonin gene-related peptide in upper spinal cord promotes sensitization of primary trigeminal nociceptive neurons

(2016) Lauren E. Cornelison et al.   NEUROSCIENCE

Neurotrophin selectivity in organizing topographic regeneration of nociceptive afferents

(2015) Lakshmi Kelamangalath et al.   EXPERIMENTAL NEUROLOGY

Calcitonin gene-related peptide pre-administration acts as a novel antidepressant in stressed mice

(2015) Narumi Hashikawa-Hobara et al.   Scientific Reports

Anti-nerve growth factor antibody attenuates chronic morphine treatment-induced tolerance in the rat

(2015) Bopaiah P. Cheppudira et al.   BMC Anesthesiology

Osteoarthritis joint pain: The cytokine connection

(2014) Rachel E. Miller et al.   CYTOKINE

In Vivo Regulation of NGF-Mediated Functions by Nedd4-2 Ubiquitination of TrkA

(2014) T. Yu et al.   JOURNAL OF NEUROSCIENCE

PCSD1, a new patient-derived model of bone metastatic prostate cancer, is castrate-resistant in the bone-niche

(2014) Elana Godebu et al.   Journal of Translational Medicine

Functional distinction between NGF-mediated plasticity and regeneration of nociceptive axons within the spinal cord

(2014) C.-L. Lin et al.   NEUROSCIENCE

Development of a novel antibody to calcitonin gene-related peptide for the treatment of osteoarthritis-related pain

(2014) R.J. Benschop et al.   OSTEOARTHRITIS AND CARTILAGE

Bone cancer pain

(2014) Patrick W. Mantyh   Current Opinion in Supportive and Palliative Care

Peptidergic CGRPα Primary Sensory Neurons Encode Heat and Itch and Tonically Suppress Sensitivity to Cold

(2013) Eric S. McCoy et al.   NEURON

The CGRP receptor antagonist BIBN4096BS peripherally alleviates inflammatory pain in rats

(2013) Silke Hirsch et al.   PAIN

Control of Neuropathic Pain by Immune Cells and Opioids

(2012) Halina Machelska   CNS & Neurological Disorders-Drug Targets

A subpopulation of nociceptors specifically linked to itch

(2012) Liang Han et al.   NATURE NEUROSCIENCE

Immune conditions associated with CD4+ T effector-induced opioid release and analgesia

(2011) Jérôme Boué et al.   PAIN

T lymphocytes containing β-endorphin ameliorate mechanical hypersensitivity following nerve injury

(2010) Dominika Labuz et al.   BRAIN BEHAVIOR AND IMMUNITY

Role of Low-Affinity Nerve Growth Factor Receptor Inhibitory Antibody in Reducing Pain Behavior and Calcitonin Gene-Related Peptide Expression in a Rat Model of Wrist Joint Inflammatory Pain

(2010) Nahoko Iwakura et al.   JOURNAL OF HAND SURGERY-AMERICAN VOLUME

The neuro-immune balance in neuropathic pain: Involvement of inflammatory immune cells, immune-like glial cells and cytokines

(2010) Paul J. Austin et al.   JOURNAL OF NEUROIMMUNOLOGY

Inhibiting nerve growth factor or its receptors downregulates calcitonin gene-related peptide expression in rat lumbar dorsal root ganglia innervating injured intervertebral discs

(2010) Sumihisa Orita et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Effect of applying p75NTR saporin to a punctured intervertebral disc on calcitonin gene-related peptide expression in rat dorsal root ganglion neurons

(2010) Ai Sugiura et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

Interactions between the immune and nervous systems in pain

(2010) Ke Ren et al.   NATURE MEDICINE

Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee

(2010) Nancy E. Lane et al.   NEW ENGLAND JOURNAL OF MEDICINE

CGRP receptors in the control of pain and inflammation

(2009) Silvia Benemei et al.   CURRENT OPINION IN PHARMACOLOGY

Low affinity NGF receptor (p75 neurotrophin receptor) inhibitory antibody reduces pain behavior and CGRP expression in DRG in the mouse sciatic nerve crush model

(2009) Yu Fukui et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Genetic Enhancement of Calcitonin Gene-Related Peptide-Induced Central Sensitization to Mechanical Stimuli in Mice

(2009) Blanca Marquez de Prado et al.   JOURNAL OF PAIN

Management of Cancer Pain: Basic Principles and Neuropathic Cancer Pain

(2008) B. Laird et al.   EUROPEAN JOURNAL OF CANCER

Challenges in cancer pain management–bone pain

(2008) L. Colvin et al.   EUROPEAN JOURNAL OF CANCER

The p75 receptor is associated with inflammatory thermal hypersensitivity

(2008) Tomoko Watanabe et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Effect of anti-NGF antibodies in a rat tibia fracture model of complex regional pain syndrome type I

(2008) Ilya Sabsovich et al.   PAIN