The basement membrane protein nidogen-1 supports platelet adhesion and activation

Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab

(2019) Christine Voors-Pette et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Molecular mechanisms of immunoreceptors in platelets

(2019) Fahd A. Kuriri et al.   THROMBOSIS RESEARCH

Platelet Signaling Pathways and New Inhibitors

(2018) Steven P. Grover et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Immobilized fibrinogen activates human platelets through glycoprotein VI

(2018) Pierre H Mangin et al.   HAEMATOLOGICA

Platelet collagen receptor Glycoprotein VI-dimer recognizes fibrinogen and fibrin through their D-domains, contributing to platelet adhesion and activation during thrombus formation

(2018) I. Induruwa et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Immobilized fibrinogen activates human platelets through glycoprotein VI

(2018) Pierre H Mangin et al.   HAEMATOLOGICA

Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks

(2017) Kristell Lebozec et al.   mAbs

The nature and biology of basement membranes

(2017) Ambra Pozzi et al.   MATRIX BIOLOGY

Unknown

(2016)   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation

(2015) E. Mammadova-Bach et al.   BLOOD

Fibrin activates GPVI in human and mouse platelets

(2015) O. M. Alshehri et al.   BLOOD

Src family kinases: at the forefront of platelet activation

(2014) Y. A. Senis et al.   BLOOD

New Fundamentals in Hemostasis

(2013) Henri H. Versteeg et al.   PHYSIOLOGICAL REVIEWS

Skin Basement Membrane: The Foundation of Epidermal Integrity—BM Functions and Diverse Roles of Bridging Molecules Nidogen and Perlecan

(2013) Dirk Breitkreutz et al.   Biomed Research International

The dimeric platelet collagen receptor GPVI-Fc reduces platelet adhesion to activated endothelium and preserves myocardial function after transient ischemia in mice

(2012) Tanja Schönberger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Different domains in nidogen-1 and nidogen-2 drive basement membrane formation in skin organotypic cocultures

(2012) Manuela Bechtel et al.   FASEB JOURNAL

Constitutive Dimerization of Glycoprotein VI (GPVI) in Resting Platelets Is Essential for Binding to Collagen and Activation in Flowing Blood

(2012) Stephanie M. Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S6K1 and mTOR regulate Rac1-driven platelet activation and aggregation

(2011) J. E. Aslan et al.   BLOOD

The extracellular matrix at a glance

(2010) C. Frantz et al.   JOURNAL OF CELL SCIENCE