Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer

A Sox2–Sox9 signalling axis maintains human breast luminal progenitor and breast cancer stem cells

(2019) Giacomo Domenici et al.   ONCOGENE

Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer

(2019) Nicole M. Kettner et al.   CLINICAL CANCER RESEARCH

ESR1 mutations in breast cancer

(2019) Derek Dustin et al.   CANCER

341PFinal results of the STEM trial: SFX-01 in the treatment and evaluation of ER+ Her2- metastatic breast cancer (mBC)

(2019) S J Howell et al.   ANNALS OF ONCOLOGY

miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer

(2019) Deepak Parashar et al.   Cell Reports

20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

(2017) Hongchao Pan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis

(2016) Rachel Eyre et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Efficacy and Safety of Abemaciclib, an Inhibitor of CDK4 and CDK6, for Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Other Solid Tumors

(2016) A. Patnaik et al.   Cancer Discovery

Accurate Prediction and Validation of Response to Endocrine Therapy in Breast Cancer

(2015) Arran K. Turnbull et al.   JOURNAL OF CLINICAL ONCOLOGY

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity

(2015) Bruno M. Simões et al.   Cell Reports

Targeting the MUC1-C oncoprotein inhibits self-renewal capacity of breast cancer cells

(2015) Maroof Alam et al.   Oncotarget

STAT3 Signaling Is Activated Preferentially in Tumor-Initiating Cells in Claudin-Low Models of Human Breast Cancer

(2014) Wei Wei et al.   STEM CELLS

Stability of sulforaphane for topical formulation

(2013) Stephen J. Franklin et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Sox2 promotes tamoxifen resistance in breast cancer cells

(2013) Marco Piva et al.   EMBO Molecular Medicine

MUC1-C Oncoprotein Activates ERK→C/EBPβ Signaling and Induction of Aldehyde Dehydrogenase 1A1 in Breast Cancer Cells

(2013) Maroof Alam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Breast cancer: Current and future endocrine therapies

(2013) Carlo Palmieri et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Oncogenic MUC1-C Promotes Tamoxifen Resistance in Human Breast Cancer

(2013) Akriti Kharbanda et al.   MOLECULAR CANCER RESEARCH

Oncostatin-M promotes phenotypic changes associated with mesenchymal and stem cell-like differentiation in breast cancer

(2013) N R West et al.   ONCOGENE

Evaluation of STAT3 Signaling in ALDH+ and ALDH+/CD44+/CD24− Subpopulations of Breast Cancer Cells

(2013) Li Lin et al.   PLoS One

Oncostatin M suppresses oestrogen receptor-α expression and is associated with poor outcome in human breast cancer

(2012) Nathan R West et al.   ENDOCRINE-RELATED CANCER

A Detailed Mammosphere Assay Protocol for the Quantification of Breast Stem Cell Activity

(2012) Frances L. Shaw et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Modeling of response to endocrine therapy in a panel of human luminal breast cancer xenografts

(2011) P. Cottu et al.   BREAST CANCER RESEARCH AND TREATMENT

Metabolism and Tissue Distribution of Sulforaphane in Nrf2 Knockout and Wild-Type Mice

(2011) John D. Clarke et al.   PHARMACEUTICAL RESEARCH

Effects of estrogen on the proportion of stem cells in the breast

(2010) Bruno M. Simões et al.   BREAST CANCER RESEARCH AND TREATMENT

Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content

(2010) Salvatore Pece et al.   CELL

Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells

(2010) Y. Li et al.   CLINICAL CANCER RESEARCH

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment

(2009) S. P. Pitroda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

(2009) C. J. Creighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA