HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α

Hsp47 promotes cancer metastasis by enhancing collagen-dependent cancer cell-platelet interaction

(2020) Gaofeng Xiong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NMIIA promotes tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway and EMT in pancreatic cancer

(2019) Pingting Zhou et al.   ONCOGENE

Matrix Metalloproteinase Inhibitors in Cancer Therapy: Turning Past Failures Into Future Successes

(2018) Arthur Winer et al.   MOLECULAR CANCER THERAPEUTICS

Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α

(2018) Denisse Sepulveda et al.   MOLECULAR CELL

The heat shock protein 47 as a potential biomarker and a therapeutic agent in cancer research

(2018) Beatriz Dal Pont Duarte et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

(2018) Susan E. Logue et al.   Nature Communications

Roles of the endoplasmic reticulum–resident, collagen-specific molecular chaperone Hsp47 in vertebrate cells and human disease

(2018) Shinya Ito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomics analysis of differential protein expression identifies heat shock protein 47 as a predictive marker for lymph node metastasis in patients with colorectal cancer

(2017) Koichiro Mori et al.   INTERNATIONAL JOURNAL OF CANCER

Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells

(2017) X-X Li et al.   ONCOGENE

Biology of Hsp47 (Serpin H1), a collagen-specific molecular chaperone

(2017) Shinya Ito et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Ancestry & molecular evolutionary analyses of heat shock protein 47 kDa (HSP47/SERPINH1)

(2017) Abhishek Kumar et al.   Scientific Reports

Chaperone Hsp47 Drives Malignant Growth and Invasion by Modulating an ECM Gene Network

(2015) J. Zhu et al.   CANCER RESEARCH

Non-muscle myosin II in disease: mechanisms and therapeutic opportunities

(2015) K. A. Newell-Litwa et al.   Disease Models & Mechanisms

Bayesian phylogeny analysis of vertebrate serpins illustrates evolutionary conservation of the intron and indels based six groups classification system from lampreys for ∼500 MY

(2015) Abhishek Kumar   PeerJ

Overexpression of MMP Family Members Functions as Prognostic Biomarker for Breast Cancer Patients: A Systematic Review and Meta-Analysis

(2015) Fanghui Ren et al.   PLoS One

Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease

(2014) Yusuke Honzawa et al.   GUT

Deletion of the Collagen-specific Molecular Chaperone Hsp47 Causes Endoplasmic Reticulum Stress-mediated Apoptosis of Hepatic Stellate Cells

(2014) Kunito Kawasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heat shock protein 47 regulated by miR-29a to enhance glioma tumor growth and invasion

(2014) Dan Zhao et al.   JOURNAL OF NEURO-ONCOLOGY

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

(2014) Xi Chen et al.   NATURE

F-actin and a Type-II Myosin Are Required for Efficient Clustering of the ER Stress Sensor Ire1

(2013) Yuki Ishiwata-Kimata et al.   CELL STRUCTURE AND FUNCTION

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Nonmuscle Myosin IIB Links Cytoskeleton to IRE1α Signaling during ER Stress

(2012) Yin He et al.   DEVELOPMENTAL CELL

Actin stress fibers - assembly, dynamics and biological roles

(2012) S. Tojkander et al.   JOURNAL OF CELL SCIENCE

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

Breast cancer signatures for invasiveness and prognosis defined by deep sequencing of microRNA

(2012) S. Volinia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using the Heat-Shock Response To Discover Anticancer Compounds that Target Protein Homeostasis

(2011) Sandro Santagata et al.   ACS Chemical Biology

The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells

(2011) Lara Derycke et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Triple-negative breast cancer: disease entity or title of convenience?

(2010) Lisa Carey et al.   Nature Reviews Clinical Oncology

Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature

(2009) Andrea Köhrmann et al.   BMC CANCER

Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions

(2009) C. Albiges-Rizo et al.   JOURNAL OF CELL SCIENCE

Identification of Proteomic Differences between Squamous Cell Carcinoma of the Lung and Bronchial Epithelium

(2009) Gereon Poschmann et al.   MOLECULAR & CELLULAR PROTEOMICS

Assembly and biological role of podosomes and invadopodia

(2008) Mario Gimona et al.   CURRENT OPINION IN CELL BIOLOGY

Nonmuscle myosin II moves in new directions

(2007) M. A. Conti et al.   JOURNAL OF CELL SCIENCE