Hydrogen improves cell viability partly through inhibition of autophagy and activation of PI3K/Akt/GSK3β signal pathway in a microvascular endothelial cell model of traumatic brain injury

Autophagy in Neurotrauma: Good, Bad, or Dysregulated

(2019) Junfang Wu et al.   Cells

Apolipoprotein E-Mimetic Peptide COG1410 Promotes Autophagy by Phosphorylating GSK-3β in Early Brain Injury Following Experimental Subarachnoid Hemorrhage

(2018) Xinshen Li et al.   Frontiers in Neuroscience

Overexpression of steroid receptor coactivators alleviates hyperglycemia-induced endothelial cell injury in rats through activating the PI3K/Akt pathway

(2018) Xiao-juan Quan et al.   ACTA PHARMACOLOGICA SINICA

Hydrogen-Rich Saline Ameliorates Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice Via the Nrf2-ARE Signaling Pathway

(2018) Yaping Liu et al.   INFLAMMATION

Nimbolide, a neem limonoid inhibits cytoprotective autophagy to activate apoptosis via modulation of the PI3K/Akt/GSK-3β signalling pathway in oral cancer

(2018) Josephraj Sophia et al.   Cell Death & Disease

Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research

(2017) Andrew I R Maas et al.   LANCET NEUROLOGY

Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats

(2017) Yuchang Xin et al.   NEUROREPORT

Posttraumatic administration of a sub-anesthetic dose of ketamine exerts neuroprotection via attenuating inflammation and autophagy

(2017) C.-Q. Wang et al.   NEUROSCIENCE

Hydrogen Gas Treatment Improves the Neurological Outcome After Traumatic Brain Injury via Increasing Mir-21 Expression

(2017) Lu Wang et al.   SHOCK

Molecular hydrogen: a preventive and therapeutic medical gas for various diseases

(2017) Li Ge et al.   Oncotarget

Protective effect of rutin against brain injury induced by acrylamide or gamma radiation: role of PI3K/AKT/GSK-3β/NRF-2 signalling pathway

(2017) Noura M. Thabet et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats

(2016) Runfa Tian et al.   BRAIN RESEARCH

Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-κB signaling pathway in experimental traumatic brain injury

(2016) YAN FENG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Small GSK-3 Inhibitor Shows Efficacy in a Motor Neuron Disease Murine Model Modulating Autophagy

(2016) Estefanía de Munck et al.   PLoS One

mTOR coordinates protein synthesis, mitochondrial activity and proliferation

(2015) Masahiro Morita et al.   CELL CYCLE

Establishment of Lipofection Protocol for Efficient miR-21 Transfection into Cortical NeuronsIn Vitro

(2015) Zhaoli Han et al.   DNA AND CELL BIOLOGY

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Protective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro

(2015) YANG YU et al.   Molecular Medicine Reports

The promise and peril of chemical probes

(2015) Cheryl H Arrowsmith et al.   Nature Chemical Biology

Autophagy at the crossroads of catabolism and anabolism

(2015) Jasvinder Kaur et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Targeting brain microvascular endothelial cells: a therapeutic approach to neuroprotection against stroke

(2015) Qi-jin Yu et al.   Neural Regeneration Research

Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury

(2014) Chinmoy Sarkar et al.   Autophagy

miR-21 alleviated apoptosis of cortical neurons through promoting PTEN-Akt signaling pathway in vitro after experimental traumatic brain injury

(2014) Zhaoli Han et al.   BRAIN RESEARCH

Molecular Hydrogen in Drinking Water Protects against Neurodegenerative Changes Induced by Traumatic Brain Injury

(2014) Kenji Dohi et al.   PLoS One

Evaluation of the Protective Potential of Brain Microvascular Endothelial Cell Autophagy on Blood–Brain Barrier Integrity During Experimental Cerebral Ischemia–Reperfusion Injury

(2014) Haiying Li et al.   Translational Stroke Research

The cell injury device: A high-throughput platform for traumatic brain injury research

(2013) Casey T. Jowers et al.   JOURNAL OF NEUROSCIENCE METHODS

Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages

(2013) Hong-Guang Chen et al.   International Journal of Surgery

Effects of the Yangjing Capsule Extract on Steroidogenesis and Apoptosis in Mouse Leydig Cells

(2012) Dalin Sun et al.   Evidence-based Complementary and Alternative Medicine

Incidence of traumatic brain injury in New Zealand: a population-based study

(2012) Valery L Feigin et al.   LANCET NEUROLOGY

Screening of Dengue Virus Antiviral Activity of Marine Seaweeds by an In Situ Enzyme-Linked Immunosorbent Assay

(2012) Andrea Cristine Koishi et al.   PLoS One

GSK-3β: a signaling pathway node modulating neural stem cell and endothelial cell interactions

(2011) Qi Li et al.   ANGIOGENESIS

GSK-3β inhibitors suppressed neuroinflammation in rat cortex by activating autophagy in ischemic brain injury

(2011) Xiaogang Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

VEGF protects rat cortical neurons from mechanical trauma injury induced apoptosis via the MEK/ERK pathway

(2011) Yihui Ma et al.   BRAIN RESEARCH BULLETIN

Drugging the PI3 Kinome: From Chemical Tools to Drugs in the Clinic

(2010) P. Workman et al.   CANCER RESEARCH

Traumatic Injury Activates MAP Kinases in Astrocytes: Mechanisms of Hypothermia and Hyperthermia

(2009) Tingting Huang et al.   JOURNAL OF NEUROTRAUMA