Reverse TCR repertoire evolution toward dominant low-affinity clones during chronic CMV infection

FLEXamers: A Double Tag for Universal Generation of Versatile Peptide-MHC Multimers

(2019) Manuel Effenberger et al.   JOURNAL OF IMMUNOLOGY

Distinct Surface Expression of Activating Receptor Ly49H Drives Differential Expansion of NK Cell Clones upon Murine Cytomegalovirus Infection

(2019) Simon Grassmann et al.   IMMUNITY

Early primed KLRG1- CMV-specific T cells determine the size of the inflationary T cell pool

(2019) Nicolas S. Baumann et al.   PLoS Pathogens

TCR repertoire evolution during maintenance of CMV-specific T-cell populations

(2018) Kilian Schober et al.   IMMUNOLOGICAL REVIEWS

Exhaustion and Inflation at Antipodes of T Cell Responses to Chronic Virus Infection

(2018) Luka Cicin-Sain et al.   TRENDS IN MICROBIOLOGY

The Contribution of Cytomegalovirus Infection to Immune Senescence Is Set by the Infectious Dose

(2018) Anke Redeker et al.   Frontiers in Immunology

Emerging Cellular Therapies for Cancer

(2018) Sonia Guedan et al.   Annual Review of Immunology

TCR Repertoire as a Novel Indicator for Immune Monitoring and Prognosis Assessment of Patients With Cervical Cancer

(2018) Jin-Huan Cui et al.   Frontiers in Immunology

Flow cytometry-based TCR-ligandKoff-rate assay for fast avidity screening of even very small antigen-specific T cell populations ex vivo

(2016) Magdalena Nauerth et al.   CYTOMETRY PART A

Linking the T cell receptor to the single cell transcriptome in antigen-specific human T cells

(2016) Auda A Eltahla et al.   IMMUNOLOGY AND CELL BIOLOGY

Senescence of T Lymphocytes: Implications for Enhancing Human Immunity

(2016) Arne N. Akbar et al.   TRENDS IN IMMUNOLOGY

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

(2015) Petter Brodin et al.   CELL

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens

(2015) Michael Hebeisen et al.   Frontiers in Immunology

Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response

(2015) Ryan J. Martinez et al.   Frontiers in Immunology

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue

(2013) Anna M. Sherwood et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The clinical potential for koff-rate measurement in adoptive immunotherapy

(2013) Magdalena Nauerth et al.   Expert Review of Clinical Immunology

The Context of Gene Expression Defines the Immunodominance Hierarchy of Cytomegalovirus Antigens

(2013) I. Dekhtiarenko et al.   JOURNAL OF IMMUNOLOGY

Age-Associated Increase of Low-Avidity Cytomegalovirus-Specific CD8+ T Cells That Re-Express CD45RA

(2013) S. J. Griffiths et al.   JOURNAL OF IMMUNOLOGY

Transcriptional insights into the CD8+ T cell response to infection and memory T cell formation

(2013) J Adam Best et al.   NATURE IMMUNOLOGY

MHC Multimer-Guided and Cell Culture-Independent Isolation of Functional T Cell Receptors from Single Cells Facilitates TCR Identification for Immunotherapy

(2013) Georg Dössinger et al.   PLoS One

Disparate Individual Fates Compose Robust CD8+ T Cell Immunity

(2013) V. R. Buchholz et al.   SCIENCE

TCR-Ligand koff Rate Correlates with the Protective Capacity of Antigen-Specific CD8+ T Cells for Adoptive Transfer

(2013) M. Nauerth et al.   Science Translational Medicine

Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection

(2012) Sarah Enouz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Methods for diversity and overlap analysis in T-cell receptor populations

(2012) Grzegorz A. Rempala et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Clonotype Selection and Composition of Human CD8 T Cells Specific for Persistent Herpes Viruses Varies with Differentiation but Is Stable Over Time

(2009) E. M. Iancu et al.   JOURNAL OF IMMUNOLOGY

Complete but curtailed T-cell response to very low-affinity antigen

(2009) Dietmar Zehn et al.   NATURE

Endogenous Naive CD8+ T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection

(2008) Joshua J. Obar et al.   IMMUNITY