Recent Advances in the Synthesis of Oxazole-Based Molecules via van Leusen Oxazole Synthesis

The LANCA three-component reaction to highly substituted β-ketoenamides – versatile intermediates for the synthesis of functionalized pyridine, pyrimidine, oxazole and quinoxaline derivatives

(2019) Tilman Lechel et al.   Beilstein Journal of Organic Chemistry

MCR Scaffolds Get Hotter with 18F-Labeling

(2019) Tryfon Zarganes-Tzitzikas et al.   MOLECULES

Isocyanide Reactions Toward the Synthesis of 3-(Oxazol-5-yl)Quinoline-2-Carboxamides and 5-(2-Tosylquinolin-3-yl)Oxazole

(2019) Zahra Yasaei et al.   Frontiers in Chemistry

Overview on Recent Approaches towards Synthesis of 2‐Keto‐annulated Oxazole Derivatives

(2019) Nayyef Aljaar et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Design, synthesis and biological evaluation of imidazole and oxazole fragments as HIV-1 integrase-LEDGF/p75 disruptors and inhibitors of microbial pathogens

(2019) Thompho J. Rashamuse et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Recent advance in oxazole-based medicinal chemistry

(2018) Hui-Zhen Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Naphthoxazoles by Photocyclization of 4-/5-(Phenylethenyl)oxazoles

(2018) Ivana Šagud et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The Dakin-West reaction: Past, present and future

(2018) Luciana Dalla Vechia et al.   TETRAHEDRON

Libraries of C-5 Substituted Imidazoles and Oxazoles by Sequential Van Leusen (VL)-Suzuki, VL-Heck and VL-Sonogashira in Imidazolium-ILs with Piperidine-Appended-IL as Base

(2018) Hemantkumar M. Savanur et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Therapeutic potential of oxazole scaffold: a patent review (2006–2017)

(2018) Ramandeep Kaur et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Oxazole-based compounds as anticancer agents

(2018) Maria A. Chiacchio et al.   CURRENT MEDICINAL CHEMISTRY

Synthesis of Multi-Substituted Pyrrole Derivatives Through [3+2] Cycloaddition with Tosylmethyl Isocyanides (TosMICs) and Electron-Deficient Compounds

(2018) Zhengning Ma et al.   MOLECULES

Synthesis and antifungal activity of novel indole-replaced streptochlorin analogues

(2017) Ming-Zhi Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives

(2017) Yogita K. Abhale et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and molecular modelling studies of phenyl linked oxadiazole-phenylhydrazone hybrids as potent antileishmanial agents

(2017) Muhammad Taha et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of a new series of 3,5-disubstituted isoxazoles active against Trypanosoma cruzi and Leishmania amazonensis

(2017) Rafael da Rosa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Investigation of ‘Head-to-Tail’-Connected Oligoaryl N,O-Ligands as Recognition Motifs for Cancer-Relevant G-Quadruplexes

(2017) Natalia Rizeq et al.   MOLECULES

Improvement of the Van Leusen reaction in the presence of β-cyclodextrin: a green and efficient synthesis of oxazoles in water

(2017) Golnaz Rahimzadeh et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES

Isoxazole Alters Metabolites and Gene Expression, Decreasing Proliferation and Promoting a Neuroendocrine Phenotype in β-Cells

(2016) Michael A. Kalwat et al.   ACS Chemical Biology

1,2,3-Triazole-based inhibitors of Porphyromonas gingivalis adherence to oral streptococci and biofilm formation

(2016) Pravin C. Patil et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Experimental and theoretical investigation of new furan and thiophene derivatives containing oxazole, isoxazole, or isothiazole subunits

(2016) Pervin Ünal Civcir et al.   STRUCTURAL CHEMISTRY

A One-Pot Tandem Approach for the Synthesis of 5-(Het)aryloxazoles from Substituted (Het)aryl Methyl Alcohols and Benzyl Bromides

(2016) Kanchugarakoppal Rangappa et al.   SYNLETT

Discovery of the disubstituted oxazole analogues as a novel class anti-tuberculotic agents against MDR- and XDR-MTB

(2015) Dongsheng Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological activity of 5-(4-methoxyphenyl)-oxazole derivatives

(2015) Daisuke Yamamuro et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Phenoxymethyl 1,3-oxazoles and 1,2,4-oxadiazoles as potent and selective agonists of free fatty acid receptor 1 (GPR40)

(2015) Ihor Zahanich et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model

(2015) Maria Grazia Perrone et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Alkyl Sulfinates: Formal Nucleophiles for Synthesizing TosMIC Analogs

(2015) J. Armando Lujan-Montelongo et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Ribosome-Mediated Incorporation of Dipeptides and Dipeptide Analogues into Proteins in Vitro

(2015) Rumit Maini et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformationally Flexible C 3-Symmetric 1,3-Oxazoles as Molecular Scaffolds

(2015) Shailesh Shah et al.   SYNLETT

Synthesis of a ‘Propeller-Like’ Oligoheteroaryl with Alternating Pyridine and Oxazole Motifs

(2015) Savvas Georgiades et al.   SYNLETT

Synthesis, characterization and comparative study the microbial activity of some heterocyclic compounds containing oxazole and benzothiazole moieties

(2015) Ivan H.R. Tomi et al.   Journal of Saudi Chemical Society

Photochemical approach to functionalized benzobicyclo[3.2.1]octene structures via fused oxazoline derivatives from 4- and 5-(o-vinylstyryl)oxazoles

(2014) Ivana Šagud et al.   Beilstein Journal of Organic Chemistry

Novel quinuclidinyl heteroarylcarbamate derivatives as muscarinic receptor antagonists

(2014) Shinya Nagashima et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of pyridyl sulfonamide 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors for the treatment of metabolic disorders

(2014) David S. Yoon et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Derivatives of imidazotriazine and pyrrolotriazine C-nucleosides as potential new anti-HCV agents

(2014) Alistair G. Draffan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, Synthesis, and Characterization of α-Ketoheterocycles That Additionally Target the Cytosolic Port Cys269 of Fatty Acid Amide Hydrolase

(2014) Katerina Otrubova et al.   JOURNAL OF MEDICINAL CHEMISTRY

Metabolism of the phytoalexins camalexins, their bioisosteres and analogues in the plant pathogenic fungus Alternaria brassicicola

(2013) M. Soledade C. Pedras et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structure–activity relationships of 2-aminothiazoles effective against Mycobacterium tuberculosis

(2013) Anja Meissner et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of a new HIV-1 inhibitor scaffold and synthesis of potential prodrugs of indazoles

(2013) Se-Ho Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Simplified captopril analogues as NDM-1 inhibitors

(2013) Ningning Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Concise and Rapid Approach to the Marine Natural Product Streptochlorin and its Analogues

(2013) Jong Seok Lee et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Gold-catalyzed oxazoles synthesis and their relevant antiproliferative activities

(2013) Chao Wu et al.   CHINESE CHEMICAL LETTERS

Synthesis and antiviral activity of a novel class of (5-oxazolyl)phenyl amines

(2013) Zhao-Jin Zhong et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of the first inhibitors of bacterial enzyme d-aspartate ligase from Enterococcus faecium (Aslfm)

(2013) Veronika Škedelj et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and fungicidal activity of novel pimprinine analogues

(2012) Ming-Zhi Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

On the structure of aspongopusin recently isolated from Aspongopus chinensis

(2012) Xiao-Wei Lu et al.   FITOTERAPIA

An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G-Quadruplex Topologies

(2011) Florian Hamon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photochemical Approach to Naphthoxazoles and Fused Heterobenzoxazoles from 5-(Phenyl/heteroarylethenyl)oxazoles

(2011) Ivana Šagud et al.   JOURNAL OF ORGANIC CHEMISTRY

One-Pot Van Leusen Synthesis of 4,5-Disubstituted Oxazoles in Ionic Liquids

(2009) Xiao-Qi Yu et al.   SYNLETT

Isocyanide-based multicomponent reactions in drug discovery

(2008) Irini Akritopoulou-Zanze   CURRENT OPINION IN CHEMICAL BIOLOGY