General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model

Title
General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model
Authors
Keywords
1,2,3-Triazoles, COX inhibition, Predictive pharmacometric model, Volsurf plus
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 94, Issue -, Pages 252-264
Publisher
Elsevier BV
Online
2015-03-01
DOI
10.1016/j.ejmech.2015.02.049

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