Sigma‐1 receptor activation‐induced glycolytic ATP production and endothelial barrier enhancement

The role of glycolysis and mitochondrial respiration in the formation and functioning of endothelial tip cells during angiogenesis

(2019) Bahar Yetkin-Arik et al.   Scientific Reports

Sigma-1 receptor activation alleviates blood-brain barrier dysfunction in vascular dementia mice

(2018) Dan-Yang Liu et al.   EXPERIMENTAL NEUROLOGY

Involvement of the delayed rectifier outward potassium channel Kv2.1 in methamphetamine-induced neuronal apoptosis via the p38 mitogen-activated protein kinase signaling pathway

(2018) Jingying Zhu et al.   JOURNAL OF APPLIED TOXICOLOGY

Sigma-1 Receptor Antagonist (BD1047) Decreases Cathepsin B Secretion in HIV-Infected Macrophages Exposed to Cocaine

(2018) Omar Vélez López et al.   Journal of Neuroimmune Pharmacology

Sphingosine-1-phosphate protects against brain microvascular endothelial junctional protein disorganization and barrier dysfunction caused by alcohol

(2018) Natascha G. Alves et al.   MICROCIRCULATION

Sphingosine-1-Phosphate Reduces Hemorrhagic Shock and Resuscitation-Induced Microvascular Leakage by Protecting Endothelial Mitochondrial Integrity

(2018) Natascha G. Alves et al.   SHOCK

Cardiac Dysfunction in the Sigma 1 Receptor Knockout Mouse Associated With Impaired Mitochondrial Dynamics and Bioenergetics

(2018) Chowdhury S. Abdullah et al.   Journal of the American Heart Association

Sigma-1 Receptor Agonists Induce Oxidative Stress in Mitochondria and Enhance Complex I Activity in Physiological Condition but Protect Against Pathological Oxidative Stress

(2017) Nino Goguadze et al.   NEUROTOXICITY RESEARCH

Central Role of Metabolism in Endothelial Cell Function and Vascular Disease

(2017) Laura Bierhansl et al.   PHYSIOLOGY

Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel

(2017) Kang Zhang et al.   Frontiers in Pharmacology

How Endothelial Cells Adapt Their Metabolism to Form Vessels in Tumors

(2017) Annalisa Zecchin et al.   Frontiers in Immunology

Mitochondrial uncoupler carbonyl cyanide m-chlorophenylhydrazone induces vasorelaxation without involving KATPchannel activation in smooth muscle cells of arteries

(2016) Yan-Qiu Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Glycolytic regulation of cell rearrangement in angiogenesis

(2016) Bert Cruys et al.   Nature Communications

Rnd3 as a Novel Target to Ameliorate Microvascular Leakage

(2016) Jerome W. Breslin et al.   Journal of the American Heart Association

Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement

(2016) Xun E. Zhang et al.   PLoS One

Histamine activates p38 MAP kinase and alters local lamellipodia dynamics, reducing endothelial barrier integrity and eliciting central movement of actin fibers

(2015) Shaquria P. Adderley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Endothelial Cell Metabolism in Normal and Diseased Vasculature

(2015) Guy Eelen et al.   CIRCULATION RESEARCH

The involvement of the sigma-1 receptor in neurodegeneration and neurorestoration

(2015) Karsten Ruscher et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Involvement of Local Lamellipodia in Endothelial Barrier Function

(2015) Jerome W. Breslin et al.   PLoS One

A Direct Interaction between the Sigma-1 Receptor and the hERG Voltage-gated K+Channel Revealed by Atomic Force Microscopy and Homogeneous Time-resolved Fluorescence (HTRF®)

(2014) Dilshan Balasuriya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Depolarization of Mitochondria in Endothelial Cells Promotes Cerebral Artery Vasodilation by Activation of Nitric Oxide Synthase

(2013) Prasad V.G. Katakam et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Treatment with afobazole at delayed time points following ischemic stroke improves long-term functional and histological outcomes

(2013) C. Katnik et al.   NEUROBIOLOGY OF DISEASE

Sigma-1 receptor agonist PRE084 is protective against mutant huntingtin-induced cell degeneration: involvement of calpastatin and the NF-κB pathway

(2013) A Hyrskyluoto et al.   Cell Death & Disease

Inhibition of endothelial cell Ca2+entry and transient receptor potential channels by Sigma-1 receptor ligands

(2012) Mohamed S Amer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

σ1-Receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunction in mice

(2010) Hideaki Tagashira et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Lymphatic Endothelial Cells Adapt Their Barrier Function in Response to Changes in Shear Stress

(2010) Jerome W. Breslin et al.   Lymphatic Research and Biology

Angiopoietin-1 inhibits intrinsic apoptotic signaling and vascular hyperpermeability following hemorrhagic shock

(2008) Ed W. Childs et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Role of Sigma-1 Receptor C-terminal Segment in Inositol 1,4,5-Trisphosphate Receptor Activation

(2008) Zhiping Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Antiamnesic and Neuroprotective Effects of the Aminotetrahydrofuran Derivative ANAVEX1-41 Against Amyloid β25–35-Induced Toxicity in Mice

(2008) Vanessa Villard et al.   NEUROPSYCHOPHARMACOLOGY