Inhibition of proprotein convertase subtilisin/kexin type 9 attenuates 2,4,6‐trinitrobenzenesulfonic acid‐induced colitis via repressing toll‐like receptor 4/nuclear factor‐kappa B

Wnt signaling in intestinal inflammation

(2019) Lavanya Moparthi et al.   DIFFERENTIATION

Donkey milk lysozyme ameliorates dextran sulfate sodium-induced colitis by improving intestinal barrier function and gut microbiota composition

(2018) Lun Jiang et al.   Journal of Functional Foods

PCSK9 induces a pro-inflammatory response in macrophages

(2018) Chiara Ricci et al.   Scientific Reports

Melatonin ameliorates TNBS-induced colitis in rats through the melatonin receptors: involvement of TLR4/MyD88/NF-κB signalling pathway

(2018) Mohsen Chamanara et al.   INFLAMMOPHARMACOLOGY

The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE*3Leiden.CETP mice

(2017) Christine Landlinger et al.   EUROPEAN HEART JOURNAL

Role of PCSK9 in the Development of Mouse Periodontitis Before and After Treatment: A Double-Edged Sword

(2017) Hua Ling Sun et al.   JOURNAL OF INFECTIOUS DISEASES

rSj16 Protects against DSS-Induced Colitis by Inhibiting the PPAR-α Signaling Pathway

(2017) Lifu Wang et al.   Theranostics

STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis

(2017) Jeonghyun Ahn et al.   Cell Reports

How to Diagnose and Treat IBD Mimics in the Refractory IBD Patient Who Does Not Have IBD

(2016) Karen A. Chachu et al.   INFLAMMATORY BOWEL DISEASES

Control of inflammation by stromal Hedgehog pathway activation restrains colitis

(2016) John J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Expression of PCSK9 Modulates Infection, Inflammation, and Coagulation in a Murine Model of Sepsis

(2016) Dhruva J. Dwivedi et al.   SHOCK

Atorvastatin attenuates TNBS-induced rat colitis: the involvement of the TLR4/NF-kB signaling pathway

(2016) Amir Rashidian et al.   INFLAMMOPHARMACOLOGY

The anti-inflammatory effect and potential mechanism of cardamonin in DSS-induced colitis

(2015) Gaiyan Ren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

TLR4/NF-κB Signaling Contributes to Chronic Unpredictable Mild Stress-Induced Atherosclerosis in ApoE-/- Mice

(2015) Ya Ling Tang et al.   PLoS One

Melatonin as a proteasome inhibitor. Is there any clinical evidence?

(2014) Jerry Vriend et al.   LIFE SCIENCES

Dietary α-mangostin, a xanthone from mangosteen fruit, exacerbates experimental colitis and promotes dysbiosis in mice

(2014) Fabiola Gutierrez-Orozco et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Qing Hua Chang Yin exerts therapeutic effects against ulcerative colitis through the inhibition of the TLR4/NF-κB pathway

(2013) XIAO KE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

PCSK9—an exciting target for reducing LDL-cholesterol levels

(2013) D. John Betteridge   Nature Reviews Endocrinology

Unexpected roles for PCSK9 in lipid metabolism

(2011) Anne K Soutar   CURRENT OPINION IN LIPIDOLOGY

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

(2011) Natalie A. Molodecky et al.   GASTROENTEROLOGY

Regulation of the Inflammatory Response: Enhancing Neutrophil Infiltration under Chronic Inflammatory Conditions

(2011) Z. Bian et al.   JOURNAL OF IMMUNOLOGY

Toll-like receptors in inflammatory bowel diseases: A decade later

(2010) Elke Cario   INFLAMMATORY BOWEL DISEASES

A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis

(2009) Ryan Ungaro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response

(2009) K. Brandl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammation stimulates the expression of PCSK9

(2008) Kenneth R. Feingold et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NF-κB in inflammatory bowel disease

(2008) I. Atreya et al.   JOURNAL OF INTERNAL MEDICINE