Coronavirus Endoribonuclease and Deubiquitinating Interferon Antagonists Differentially Modulate the Host Response during Replication in Macrophages

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus

(2020) Xufang Deng et al.   JOURNAL OF VIROLOGY

Coronavirus endoribonuclease activity in porcine epidemic diarrhea virus suppresses type I and type III interferon responses

(2019) Xufang Deng et al.   JOURNAL OF VIROLOGY

Combination attenuation offers strategy for live-attenuated coronavirus vaccines

(2018) Vineet D. Menachery et al.   JOURNAL OF VIROLOGY

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update

(2018) Enis Afgan et al.   NUCLEIC ACIDS RESEARCH

Genome-wide identification of interferon-sensitive mutations enables influenza vaccine design

(2018) Yushen Du et al.   SCIENCE

The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species

(2018) Daniela Niemeyer et al.   PLoS Pathogens

Origin and evolution of pathogenic coronaviruses

(2018) Jie Cui et al.   NATURE REVIEWS MICROBIOLOGY

Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages

(2017) Xufang Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis

(2017) Vineet D. Menachery et al.   mBio

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

(2017) Eveline Kindler et al.   PLoS Pathogens

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis

(2017) Vineet D. Menachery et al.   mSphere

Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

(2016) Rudragouda Channappanavar et al.   Cell Host & Microbe

Molecular Mechanisms of Innate Immune Inhibition by Non-Segmented Negative-Sense RNA Viruses

(2016) Srirupa Chatterjee et al.   JOURNAL OF MOLECULAR BIOLOGY

The Many Faces of the Flavivirus NS5 Protein in Antagonism of Type I Interferon Signaling

(2016) Sonja M. Best   JOURNAL OF VIROLOGY

Regulation of Stress Responses and Translational Control by Coronavirus

(2016) To Fung et al.   Viruses-Basel

Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

(2016) Huib H. Rabouw et al.   PLoS Pathogens

Vaccinia Virus Protein C6 Inhibits Type I IFN Signalling in the Nucleus and Binds to the Transactivation Domain of STAT2

(2016) Jennifer H. Stuart et al.   PLoS Pathogens

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

The Interferon Signaling Antagonist Function of Yellow Fever Virus NS5 Protein Is Activated by Type I Interferon

(2014) Maudry Laurent-Rolle et al.   Cell Host & Microbe

To sense or not to sense viral RNA—essentials of coronavirus innate immune evasion

(2014) Eveline Kindler et al.   CURRENT OPINION IN MICROBIOLOGY

Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease

(2014) Kiira Ratia et al.   PLoS Pathogens

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

MERS-CoV papain-like protease has deISGylating and deubiquitinating activities

(2013) Anna M. Mielech et al.   VIROLOGY

SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon

(2012) Allison L Totura et al.   Current Opinion in Virology

Autocrine Interferon Priming in Macrophages but Not Dendritic Cells Results in Enhanced Cytokine and Chemokine Production after Coronavirus Infection

(2010) H. Zhou et al.   mBio

Virus-Induced Unfolded Protein Response Attenuates Antiviral Defenses via Phosphorylation-Dependent Degradation of the Type I Interferon Receptor

(2009) Jianghuai Liu et al.   Cell Host & Microbe

Severe Acute Respiratory Syndrome Coronavirus Papain-Like Protease Ubiquitin-Like Domain and Catalytic Domain Regulate Antagonism of IRF3 and NF- B Signaling

(2009) M. Frieman et al.   JOURNAL OF VIROLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Coronaviruses post-SARS: update on replication and pathogenesis

(2009) Stanley Perlman et al.   NATURE REVIEWS MICROBIOLOGY

Coronavirus Infection Modulates the Unfolded Protein Response and Mediates Sustained Translational Repression

(2008) J. Bechill et al.   JOURNAL OF VIROLOGY

Murine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia

(2008) J. K. Roth-Cross et al.   JOURNAL OF VIROLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH