Efficacy and safety of recombinant human soluble thrombomodulin in patients with sepsis‐associated coagulopathy: A systematic review and meta‐analysis

Recombinant Human Soluble Thrombomodulin in Sepsis-Induced Coagulopathy: An Updated Systematic Review and Meta-Analysis

(2019) Shuhei Murao et al.   THROMBOSIS AND HAEMOSTASIS

Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis

(2019) Christopher W. Seymour et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy

(2019) Jean-Louis Vincent et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Multicenter clinical experience with recombinant soluble thrombomodulin for disseminated intravascular coagulation associated with severe acute cholecystitis

(2019) Takeshi Ogura et al.   THROMBOSIS RESEARCH

Human Soluble Recombinant Thrombomodulin, ART-123, Resolved Early Phase Coagulopathies, but Did Not Significantly Alter the 28 Day Outcome in the Treatment of DIC Associated with Infectious Systemic Inflammatory Response Syndromes

(2019) Shusuke Mori et al.   Journal of Clinical Medicine

Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters

(2018) Timothy E. Sweeney et al.   CRITICAL CARE MEDICINE

Sepsis-Associated Coagulopathy Severity Predicts Hospital Mortality*

(2018) Patrick G. Lyons et al.   CRITICAL CARE MEDICINE

Clinical Impact of Recombinant Soluble Thrombomodulin for Disseminated Intravascular Coagulation Associated with Severe Acute Cholangitis

(2018) Atsushi Okuda et al.   Gut and Liver

Antithrombin concentrate use in disseminated intravascular coagulation of sepsis: meta-analyses revisited

(2018) C. J. Wiedermann   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Coagulation and sepsis

(2017) Marcel Levi et al.   THROMBOSIS RESEARCH

New criteria for sepsis-induced coagulopathy (SIC) following the revised sepsis definition: a retrospective analysis of a nationwide survey

(2017) Toshiaki Iba et al.   BMJ Open

Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations

(2016) Carolin Fleischmann et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Efficacy and safety of anticoagulant therapy in three specific populations with sepsis: a meta-analysis of randomized controlled trials

(2016) Y. Umemura et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Can recombinant human thrombomodulin increase survival among patients with severe septic-induced disseminated intravascular coagulation: a single-centre, open-label, randomised controlled trial

(2016) Akiyoshi Hagiwara et al.   BMJ Open

Thrombomodulin in the management of acute cholangitis-induced disseminated intravascular coagulation

(2015) Keigo Suetani   WORLD JOURNAL OF GASTROENTEROLOGY

Sepsis: From Pathophysiology to Individualized Patient Care

(2015) Ildikó László et al.   Journal of Immunology Research

Recombinant human soluble thrombomodulin and mortality in severe pneumonia patients with sepsis-associated disseminated intravascular coagulation: an observational nationwide study

(2014) T. Tagami et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Evaluate the Safety and Efficacy of Recombinant Human Soluble Thrombomodulin, ART-123, in Patients With Sepsis and Suspected Disseminated Intravascular Coagulation*

(2013) Jean-Louis Vincent et al.   CRITICAL CARE MEDICINE

Thrombomodulin Links Coagulation to Inflammation and Immunity

(2012) John Morser   CURRENT DRUG TARGETS

THROMBOMODULIN ALFA IN THE TREATMENT OF INFECTIOUS PATIENTS COMPLICATED BY DISSEMINATED INTRAVASCULAR COAGULATION

(2010) Naoki Aikawa et al.   SHOCK

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE