THROMBOMODULIN ALFA IN THE TREATMENT OF INFECTIOUS PATIENTS COMPLICATED BY DISSEMINATED INTRAVASCULAR COAGULATION

IN VIVO AND IN VITRO EFFECTS OF THE ANTICOAGULANT, THROMBOMODULIN, ON THE INFLAMMATORY RESPONSE IN RODENT MODELS

(2010) Satoshi Hagiwara et al.   SHOCK

Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality

(2009) F. Niessen et al.   BLOOD

Guidelines for the diagnosis and management of disseminated intravascular coagulation

(2009) M Levi et al.   BRITISH JOURNAL OF HAEMATOLOGY

Recombinant human soluble thrombomodulin decreases the plasma high-mobility group box-1 protein levels, whereas improving the acute liver injury and survival rates in experimental endotoxemia

(2009) Masaru Nagato et al.   CRITICAL CARE MEDICINE

Proteolytic Cleavage of High Mobility Group Box 1 Protein by Thrombin-Thrombomodulin Complexes

(2008) Takashi Ito et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response

(2008) C.-S. Shi et al.   BLOOD