Claudin-2 deficiency associates with hypercalciuria in mice and human kidney stone disease

Identification of a missense variant in CLDN2 in obstructive azoospermia

(2019) Masomeh Askari et al.   JOURNAL OF HUMAN GENETICS

A continuum of mineralization from human renal pyramid to stones on stems

(2018) Benjamin A. Sherer et al.   Acta Biomaterialia

GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12

(2018) Chizu Tanikawa et al.   CARCINOGENESIS

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases

(2018) Masahiro Kanai et al.   NATURE GENETICS

Overview of the BioBank Japan Project: Study design and profile

(2017) Akiko Nagai et al.   JOURNAL OF EPIDEMIOLOGY

Overview of BioBank Japan follow-up data in 32 diseases

(2017) Makoto Hirata et al.   JOURNAL OF EPIDEMIOLOGY

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

Identification of six new genetic loci associated with atrial fibrillation in the Japanese population

(2017) Siew-Kee Low et al.   NATURE GENETICS

High frequency and wide range of human kidney papillary crystalline plugs

(2017) Léa Huguet et al.   Urolithiasis

The origins of urinary stone disease: upstream mineral formations initiate downstream Randall's plaque

(2016) Ryan S. Hsi et al.   BJU INTERNATIONAL

Paracellular epithelial sodium transport maximizes energy efficiency in the kidney

(2016) Lei Pei et al.   JOURNAL OF CLINICAL INVESTIGATION

The Tohoku Medical Megabank Project: Design and Mission

(2016) Shinichi Kuriyama et al.   JOURNAL OF EPIDEMIOLOGY

Topography, Composition and Structure of Incipient Randall Plaque at the Nanoscale Level

(2016) Cécile Verrier et al.   JOURNAL OF UROLOGY

Deletion of the intestinal plasma membrane calcium pump, isoform 1, Atp2b1 , in mice is associated with decreased bone mineral density and impaired responsiveness to 1, 25-dihydroxyvitamin D 3

(2015) Zachary C. Ryan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SPR4-peptide alters bone metabolism of normal and HYP mice

(2015) Lesya V. Zelenchuk et al.   BONE

Nephrocalcinosis in Calcium Stone Formers Who Do Not have Systemic Disease

(2015) Naeem Bhojani et al.   JOURNAL OF UROLOGY

Demographics and Characterization of 10,282 Randall Plaque-Related Kidney Stones

(2015) Emmanuel Letavernier et al.   MEDICINE

Corticomedullary difference in the effects of dietary Ca2+ on tight junction properties in thick ascending limbs of Henle’s loop

(2015) Allein Plain et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Common and rare variants associated with kidney stones and biochemical traits

(2015) Asmundur Oddsson et al.   Nature Communications

Claudin-2-dependent paracellular channels are dynamically gated

(2015) Christopher R Weber et al.   eLife

Contrasting Histopathology and Crystal Deposits in Kidneys of Idiopathic Stone Formers Who Produce Hydroxy Apatite, Brushite, or Calcium Oxalate Stones

(2014) Andrew P. Evan et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Mechanisms of human kidney stone formation

(2014) Andrew P. Evan et al.   Urolithiasis

The Na+/H+ exchanger isoform 3 is required for active paracellular and transcellular Ca2+ transport across murine cecum

(2013) Juraj Rievaj et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The aldehyde dehydrogenase 2 (ALDH2) Glu504Lys polymorphism interacts with alcohol drinking in the risk of stomach cancer

(2013) K. Matsuo et al.   CARCINOGENESIS

Demography and biochemistry of 2800 patients from a renal stones clinic

(2013) V. Walker et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Claudins and the Kidney

(2012) Jianghui Hou et al.   Annual Review of Physiology

Prevalence of Kidney Stones in the United States

(2012) Charles D. Scales et al.   EUROPEAN UROLOGY

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

(2012) David C Whitcomb et al.   NATURE GENETICS

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

(2012) Bryan Howie et al.   NATURE GENETICS

A Genome-Wide Association Study of Nephrolithiasis in the Japanese Population Identifies Novel Susceptible Loci at 5q35.3, 7p14.3, and 13q14.1

(2012) Yuji Urabe et al.   PLoS Genetics

Pathophysiology-Based Treatment of Idiopathic Calcium Kidney Stones

(2011) F. L. Coe et al.   Clinical Journal of the American Society of Nephrology

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Loss of Claudin-15, but Not Claudin-2, Causes Na+ Deficiency and Glucose Malabsorption in Mouse Small Intestine

(2010) Atsushi Tamura et al.   GASTROENTEROLOGY

Calcium Kidney Stones

(2010) Elaine M. Worcester et al.   NEW ENGLAND JOURNAL OF MEDICINE

Claudin-2–deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules

(2010) Shigeaki Muto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for altered renal tubule function in idiopathic calcium stone formers

(2010) Elaine M. Worcester et al.   UROLOGICAL RESEARCH

Association of Variants at UMOD with Chronic Kidney Disease and Kidney Stones—Role of Age and Comorbid Diseases

(2010) Daniel F. Gudbjartsson et al.   PLoS Genetics

Claudin-10 exists in six alternatively spliced isoforms that exhibit distinct localization and function

(2009) D. Gunzel et al.   JOURNAL OF CELL SCIENCE

Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density

(2009) Gudmar Thorleifsson et al.   NATURE GENETICS

Molecular Basis for Cation Selectivity in Claudin-2–based Paracellular Pores: Identification of an Electrostatic Interaction Site

(2008) Alan S.L. Yu et al.   JOURNAL OF GENERAL PHYSIOLOGY