A network pharmacology‐based approach to explore the effects of Chaihu Shugan powder on a non‐alcoholic fatty liver rat model through nuclear receptors

Homeostasis of Glucose and Lipid in Non-Alcoholic Fatty Liver Disease

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Network Pharmacology Databases for Traditional Chinese Medicine: Review and Assessment

(2019) Runzhi Zhang et al.   Frontiers in Pharmacology

Past, present and future perspectives in nonalcoholic fatty liver disease

(2019) Arun J. Sanyal   Nature Reviews Gastroenterology & Hepatology

Chaihu-Shugan-San and absorbed meranzin hydrate induce anti-atherosclerosis and behavioral improvements in high-fat diet ApoE-/- mice via anti-inflammatory and BDNF-TrkB pathway

(2019) Lan Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Naringenin and its Nano-formulations for Fatty Liver: Cellular Modes of Action and Clinical Perspective

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Pathology of non-alcoholic fatty liver disease

(2017) Pierre Bedossa   LIVER INTERNATIONAL

Long-term dietary supplementation with low-dose nobiletin ameliorates hepatic steatosis, insulin resistance, and inflammation without altering fat mass in diet-induced obesity

(2017) Young-Je Kim et al.   MOLECULAR NUTRITION & FOOD RESEARCH

How Can Synergism of Traditional Medicines Benefit from Network Pharmacology?

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Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis

(2017) Anna M. Diehl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nuclear receptors and nonalcoholic fatty liver disease 1 1This article is part of a Special Issue entitled: Xenobiotic nuclear receptors: New Tricks for An Old Dog, edited by Dr. Wen Xie.

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Protective Effects of Chaihu Shugan San (柴胡疏肝散) on Nonalcoholic Fatty Liver Disease in Rats with Insulin Resistance

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Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

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Global epidemiology of nonalcoholic fatty liver disease: Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) A. Lonardo et al.   HEPATOLOGY

Management of NAFLD: a stage-based approach

(2016) Mary E. Rinella et al.   Nature Reviews Gastroenterology & Hepatology

Obesity is an independent risk factor for non-alcoholic fatty liver disease: evidence from a meta-analysis of 21 cohort studies

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Fatty liver diseases, bile acids, and FXR

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Dietary component isorhamnetin is a PPARγ antagonist and ameliorates metabolic disorders induced by diet or leptin deficiency

(2016) Yu Zhang et al.   Scientific Reports

Nonalcoholic Fatty Liver Disease

(2015) Mary E. Rinella   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Kaempferol Isolated fromNelumbo nuciferaInhibits Lipid Accumulation and Increases Fatty Acid Oxidation Signaling in Adipocytes

(2015) Bonggi Lee et al.   JOURNAL OF MEDICINAL FOOD

Kaempferol ameliorates symptoms of metabolic syndrome by regulating activities of liver X receptor-β

(2015) Minh-Hien Hoang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of nonalcoholic fatty liver disease

(2015) Sandra Pisonero-Vaquero et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Effect of Chaihu-Shugan-San on the mRNA expression of the 5-HT1A receptor and cellular proliferation in the hippocampus of epileptic rats with depression

(2015) PING YANG et al.   Experimental and Therapeutic Medicine

Non-alcoholic fatty liver disease, obesity and the metabolic syndrome

(2014) Peter Dietrich et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Recent insights into farnesoid X receptor in non-alcoholic fatty liver disease

(2014) Jiao-Ya Xu   WORLD JOURNAL OF GASTROENTEROLOGY

All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade

(2013) Seong Chul Kim et al.   HEPATOLOGY

Looking at nuclear receptors from a new angle

(2013) Christine Helsen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Non-alcoholic fatty liver disease in obese children and the relationship between metabolic syndrome criteria

(2013) Mehmet Boyraz et al.   Obesity Research & Clinical Practice

Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells

(2013) Satyakumar Vidyashankar et al.   TOXICOLOGY IN VITRO

Roles of PPARs in NAFLD: Potential therapeutic targets

(2011) Anne Tailleux et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: Selected practical issues in their evaluation and management

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