Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of nonalcoholic fatty liver disease

CXCL10 plays a key role as an inflammatory mediator and a non-invasive biomarker of non-alcoholic steatohepatitis

(2014) Xiang Zhang et al.   JOURNAL OF HEPATOLOGY

Extracts from Salvia-Nelumbinis naturalis alleviate hepatosteatosis via improving hepatic insulin sensitivity

(2014) Li Zhang et al.   Journal of Translational Medicine

Modulation of PI3K-LXRα-dependent lipogenesis mediated by oxidative/nitrosative stress contributes to inhibition of HCV replication by quercetin

(2014) Sandra Pisonero-Vaquero et al.   LABORATORY INVESTIGATION

De novo lipogenesis in health and disease

(2014) Fatima Ameer et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The Flavones Apigenin and Luteolin Induce FOXO1 Translocation but Inhibit Gluconeogenic and Lipogenic Gene Expression in Human Cells

(2014) Christiane Bumke-Vogt et al.   PLoS One

Inflammatory Stress Increases Hepatic CD36 Translational Efficiency via Activation of the mTOR Signalling Pathway

(2014) Chuan Wang et al.   PLoS One

Lipid modulatory activities of Cichorium glandulosum Boiss et Huet are mediated by multiple components within hepatocytes

(2014) Lin Ding et al.   Scientific Reports

The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARα; and repressed by C/EBPα: Implications in FABP1 down-regulation in nonalcoholic fatty liver disease

(2013) Carla Guzmán et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats

(2013) Wei Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis

(2013) Lars P. Bechmann et al.   HEPATOLOGY

A tetrahydroisoquinoline alkaloid THI-28 reduces LPS-induced HMGB1 and diminishes organ injury in septic mice through p38 and PI3K/Nrf2/HO-1 signals

(2013) Hee Sook Kim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effects of treatment with hydrogen sulfide on methionine-choline deficient diet-induced non-alcoholic steatohepatitis in rats

(2013) Zhu-Lin Luo et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Inhibitory effects of baicalin in the early stage of 3T3-L1 preadipocytes differentiation by down-regulation of PDK1/Akt phosphorylation

(2013) Dong Hoon Kwak et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Small Heterodimer Partner-Targeting Therapy Inhibits Systemic Inflammatory Responses through Mitochondrial Uncoupling Protein 2

(2013) Chul-Su Yang et al.   PLoS One

Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells

(2013) Satyakumar Vidyashankar et al.   TOXICOLOGY IN VITRO

27-Hydroxycholesterol induces production of tumor necrosis factor-alpha from macrophages

(2012) Sun-Mi Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Non-Alcoholic Steatohepatitis: What Can We Learn from Animal Models?

(2012) C. Almonacid-Urrego et al.   CURRENT MEDICINAL CHEMISTRY

Dietary quercetin ameliorates nonalcoholic steatohepatitis induced by a high-fat diet in gerbils

(2012) Hua-Zhong Ying et al.   FOOD AND CHEMICAL TOXICOLOGY

Quercetin Ameliorates Cardiovascular, Hepatic, and Metabolic Changes in Diet-Induced Metabolic Syndrome in Rats

(2012) Sunil K. Panchal et al.   JOURNAL OF NUTRITION

Quercetin Treatment Ameliorates Inflammation and Fibrosis in Mice with Nonalcoholic Steatohepatitis1–3

(2012) Eder Marcolin et al.   JOURNAL OF NUTRITION

Liver X receptor α-mediated regulation of lipogenesis by core and NS5A proteins contributes to HCV-induced liver steatosis and HCV replication

(2012) María Victoria García-Mediavilla et al.   LABORATORY INVESTIGATION

Dietary fat source alters hepatic gene expression profile and determines the type of liver pathology in rats overfed via total enteral nutrition

(2012) M. J. J. Ronis et al.   PHYSIOLOGICAL GENOMICS

Quercetin Reduces High-Fat Diet-Induced Fat Accumulation in the Liver by Regulating Lipid Metabolism Genes

(2012) Chang Hwa Jung et al.   PHYTOTHERAPY RESEARCH

Co-Stimulation of PAFR and CD36 Is Required for oxLDL-Induced Human Macrophages Activation

(2012) Francisco J. O. Rios et al.   PLoS One

Silibinin modulates lipid homeostasis and inhibits nuclear factor kappa B activation in experimental nonalcoholic steatohepatitis

(2012) Federico Salamone et al.   Translational Research

Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

(2012) Yoshihisa Takahashi   WORLD JOURNAL OF GASTROENTEROLOGY

Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C

(2011) M. E. Miquilena-Colina et al.   GUT

Impaired Activation of Phosphatidylinositol 3-Kinase by Leptin is a Novel Mechanism of Hepatic Leptin Resistance in NAFLD

(2011) Dan Xu et al.   HEPATO-GASTROENTEROLOGY

Time-dependent changes in lipid metabolism in mice with methionine choline deficiency-induced fatty liver disease

(2011) Han-Sol Park et al.   MOLECULES AND CELLS

Transcription factor Nrf2 regulates SHP and lipogenic gene expression in hepatic lipid metabolism

(2010) Jiansheng Huang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Nonalcoholic Fatty Liver Disease: Pathology and Pathogenesis

(2010) Dina G. Tiniakos et al.   Annual Review of Pathology-Mechanisms of Disease

Fruit polyphenols, immunity and inflammation

(2010) Javier González-Gallego et al.   BRITISH JOURNAL OF NUTRITION

Enhanced expression of pro-inflammatory mediators and liver X-receptor-regulated lipogenic genes in non-alcoholic fatty liver disease and hepatitis C

(2010) Elena Lima-Cabello et al.   CLINICAL SCIENCE

Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway

(2010) Nitika Arora Gupta et al.   HEPATOLOGY

A meta-analysis of randomized trials for the treatment of nonalcoholic fatty liver disease

(2010) Giovanni Musso et al.   HEPATOLOGY

Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner

(2009) Dipanjan Chanda et al.   HEPATOLOGY

Hepatitis C virus NS5A and core proteins induce oxidative stress-mediated calcium signalling alterations in hepatocytes

(2009) Natalia Dionisio et al.   JOURNAL OF HEPATOLOGY

Cellular fatty acid uptake: a pathway under construction

(2009) Xiong Su et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A comparison of the effects of kaempferol and quercetin on cytokine-induced pro-inflammatory status of cultured human endothelial cells

(2008) Irene Crespo et al.   BRITISH JOURNAL OF NUTRITION

Diagnosis and Therapy of Nonalcoholic Steatohepatitis

(2008) Dawn M. Torres et al.   GASTROENTEROLOGY

Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease

(2008) Hironori Mitsuyoshi et al.   HEPATOLOGY RESEARCH

Effects of glutamine on proinflammatory gene expression and activation of nuclear factor kappa B and signal transducers and activators of transcription in TNBS-induced colitis

(2008) Nelson A. Kretzmann et al.   INFLAMMATORY BOWEL DISEASES

Silencing of Hepatic Fatty Acid Transporter Protein 5in VivoReverses Diet-induced Non-alcoholic Fatty Liver Disease and Improves Hyperglycemia

(2008) Holger Doege et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional Regulation of Fatty Acid Translocase/CD36 Expression by CCAAT/Enhancer-binding Protein α

(2008) Liping Qiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dietary procyanidins lower triglyceride levels signaling through the nuclear receptor small heterodimer partner

(2008) Josep Maria Del Bas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Differential effects of dietary flavonoids on reactive oxygen and nitrogen species generation and changes in antioxidant enzyme expression induced by proinflammatory cytokines in Chang Liver cells

(2007) Irene Crespo et al.   FOOD AND CHEMICAL TOXICOLOGY